| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:1000; loading ...; fig 1f, s4a
| Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed publisher |
- western blot knockout validation; human; fig 3
| Makhov P, Naito S, Haifler M, Kutikov A, Boumber Y, Uzzo R, et al. The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma. Cell Death Dis. 2018;9:374 pubmed publisher |
- western blot; human; loading ...; fig 2f
| Ko P, Choi J, Song S, Keum S, Jeong J, Hwang Y, et al. Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Int J Mol Sci. 2021;22: pubmed publisher |
- western blot; human; loading ...; fig 1a, 5b
| Johnston B, Pringle E, McCormick C. KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication. PLoS Pathog. 2019;15:e1008185 pubmed publisher |
- western blot; human; 1:200; loading ...; fig s2a
| Simic M, Moehle E, Schinzel R, Lorbeer F, Halloran J, Heydari K, et al. Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming. Sci Adv. 2019;5:eaaw0025 pubmed publisher |
- western blot; mouse; loading ...; fig 1h
| Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3b
| Jeon Y, Kim T, Park D, Nuovo G, Rhee S, Joshi P, et al. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Nat Commun. 2018;9:5110 pubmed publisher |
- western blot; human; loading ...; fig s4c
| Liang H, Xiao J, Zhou Z, Wu J, Ge F, Li Z, et al. Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis. Oncogene. 2018;37:1961-1975 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5d
| Feigenson M, Shull L, Taylor E, Camilleri E, Riester S, Van Wijnen A, et al. Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development. J Bone Miner Res. 2017;32:2453-2465 pubmed publisher |
- western blot; human; 1:3000; loading ...; fig 5a
| Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X. PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Exp Ther Med. 2017;13:1993-1999 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Li J, Yakushi T, Parlati F, MacKinnon A, Pérez C, Ma Y, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017;13:486-493 pubmed publisher |
- western blot; mouse; loading ...; fig s5e
| Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher |
- western blot; human; fig 2a
| Geraghty P, Baumlin N, SALATHE M, Foronjy R, D Armiento J. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm. 2016;2016:9461289 pubmed publisher |
- western blot; human; loading ...; fig s2e
| Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher |
- western blot; human; loading ...; fig 8a
- western blot; rat; loading ...; fig 4a
- western blot; mouse; loading ...; fig 3b
| Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed |
- western blot; mouse; 1:1000; fig 5
| Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher |
- western blot; human; 1:1000; fig s5
| Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2a
| Tibullo D, Barbagallo I, Giallongo C, Vanella L, Conticello C, Romano A, et al. Heme oxygenase-1 nuclear translocation regulates bortezomibinduced cytotoxicity and mediates genomic instability in myeloma cells. Oncotarget. 2016;7:28868-80 pubmed publisher |
- western blot; human; fig 4
| Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, et al. HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016;6:22487 pubmed publisher |
| Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher |
- western blot; human; 1:1000; fig 7
| Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed publisher |
- western blot; rat; 1:500; fig 1
| Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher |
- western blot; human; 1:1000
| Nagelkerke A, Sweep F, Stegeman H, Grenman R, Kaanders J, Bussink J, et al. Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma. Head Neck. 2015;37:896-905 pubmed publisher |
- western blot; mouse; 1:1000
| Han J, Kaufman R. Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity. Methods Enzymol. 2014;538:135-50 pubmed publisher |
- western blot; human; 1:500
| Peng Y, Shi Y, Ding Z, Ke A, Gu C, Hui B, et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy. 2013;9:2056-68 pubmed publisher |
| Tabbarah S, Tavares E, Charish J, Vincent A, Paterson A, Di Scipio M, et al. COG5 variants lead to complex early onset retinal degeneration, upregulation of PERK and DNA damage. Sci Rep. 2020;10:21269 pubmed publisher |
| Siddiquey M, Zhang H, Nguyen C, Domma A, Kamil J. The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response. J Virol. 2018;92: pubmed publisher |
| Ham S, Lee Y, Jo M, Kim H, Kang H, Jo A, et al. Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson's disease model. Sci Rep. 2017;7:525 pubmed publisher |
| Sabnis A, Guerriero C, Olivas V, Sayana A, Shue J, Flanagan J, et al. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016;113:9015-20 pubmed publisher |
| Bettigole S, Lis R, Adoro S, Lee A, Spencer L, Weller P, et al. The transcription factor XBP1 is selectively required for eosinophil differentiation. Nat Immunol. 2015;16:829-37 pubmed publisher |
| Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, et al. Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis. Nat Commun. 2015;6:6239 pubmed publisher |
| Soderquist R, Danilov A, Eastman A. Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. J Biol Chem. 2014;289:16190-9 pubmed publisher |
| Soderquist R, Pletnev A, Danilov A, Eastman A. The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA. Apoptosis. 2014;19:201-9 pubmed publisher |
