product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Smad2/3 Antibody
catalog :
5678
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 3d
Yang J, Sun L, Fan X, Yin B, Kang Y, Tang L, et al. Effect of exercise on bone in poorly controlled type 1 diabetes mediated by the ActRIIB/Smad signaling pathway. Exp Ther Med. 2018;16:3686-3693 pubmed publisher
  • western blot; mouse; loading ...; fig 2c
Zhu F, Zhu Q, Ye D, Zhang Q, Yang Y, Guo X, et al. Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency. Nucleic Acids Res. 2018;46:6026-6040 pubmed publisher
  • western blot; human; 1:1000; fig 2b
Park G, Kim D. Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway. Mol Med Rep. 2018;17:3563-3574 pubmed publisher
  • western blot; dog; loading ...; fig s7d
Zhang K, Myllymäki S, Gao P, Devarajan R, Kytölä V, Nykter M, et al. Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene. 2017;36:5681-5694 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 5
  • western blot; human; 1:1000; loading ...; fig 5
Liao Z, Zhao L, Cai M, Xi M, He L, Yu F, et al. P300 promotes migration, invasion and epithelial-mesenchymal transition in a nasopharyngeal carcinoma cell line. Oncol Lett. 2017;13:763-769 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 2a
Sharum I, Granados Aparici S, Warrander F, Tournant F, Fenwick M. Serine threonine kinase receptor associated protein regulates early follicle development in the mouse ovary. Reproduction. 2017;153:221-231 pubmed
  • western blot; mouse; loading ...; fig S4a
Jia D, Duan F, Peng P, Sun L, Ruan Y, Gu J. Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE. 2015;10:e0121939 pubmed publisher
  • western blot; mouse
Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
  • western blot; mouse
Yang X, Han Z, Zhang S, Zhu P, Hao C, Fan T, et al. Chronic restraint stress decreases the repair potential from mesenchymal stem cells on liver injury by inhibiting TGF-?1 generation. Cell Death Dis. 2014;5:e1308 pubmed publisher
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher
Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, et al. Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016;22:4934-4946 pubmed
Nakasaki M, Hwang Y, Xie Y, Kataria S, Gund R, Hajam E, et al. The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis. Nat Commun. 2015;6:8574 pubmed publisher
Yoon B, Esquivies L, Ahn C, Gray P, Ye S, Kwiatkowski W, et al. An activin A/BMP2 chimera, AB204, displays bone-healing properties superior to those of BMP2. J Bone Miner Res. 2014;29:1950-9 pubmed publisher
Rashmi R, Eckes B, Glockner G, Groth M, Neumann S, Gloy J, et al. The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus. 2012;3:172-86 pubmed publisher
product information
SKU :
5678S
Product-Name :
Smad2/3 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (X)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
52, 60
Host :
Rabbit
Target :
Smad2/Smad3
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.