product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PDK1 (D37A7) Rabbit mAb
catalog :
5662
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D37A7
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 4c
  • western blot; human; 1:1000; loading ...; fig 4b
Wang P, Zhao L, Gong S, Xiong S, Wang J, Zou D, et al. HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia. Cell Death Dis. 2021;12:312 pubmed publisher
  • western blot; human; 1:1000; tbl 1
Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  • western blot; mouse; fig 6
Yazlovitskaya E, Tseng H, Viquez O, Tu T, Mernaugh G, McKee K, et al. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015;26:1857-74 pubmed publisher
  • western blot; human; fig 10
  • western blot; mouse; fig 10
Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, et al. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol. 2015;35:1299-313 pubmed publisher
Guan Y, Cheng Y, Yin Y, Duan J, Wei G, Weng Y, et al. A novel animal model of impaired glucose tolerance induced by the interaction of vitamin E deficiency and (60)Co radiation. Biomed Res Int. 2015;2015:457246 pubmed publisher
Shanmugam V, Ramanathan R, Lavender N, Sinari S, Chadha M, Liang W, et al. Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer. BMC Med Genomics. 2014;7:36 pubmed publisher
Ling L, Voskas D, Woodgett J. Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene. 2013;32:5397-408 pubmed publisher
product information
SKU :
5662S
Product-Name :
PDK1 (D37A7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
58-68
Host :
Rabbit
Target :
PDK1
Primary-Protein :
PDK1
Alt-Names :
3-phosphoinositide dependent protein kinase-1,3-phosphoinositide-dependent protein kinase 1,MGC20087,MGC35290,PDK1,PDPK1,PRO0461,PkB kinase like gene 1,PkB-like 1,hPDK1,protein kinase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.