product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-β-Catenin (Ser552) (D8E11) Rabbit mAb
catalog :
5651
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D8E11
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunoprecipitation, immunohistochemistry - frozen section
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4b
Zhu X, Chen L, Huang B, Li X, Yang L, Hu X, et al. Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer. J Exp Clin Cancer Res. 2021;40:122 pubmed publisher
  • western blot; human; loading ...; fig 8a
Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4h
  • western blot; mouse; 1:1000; loading ...; fig 4d,4c
Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  • western blot; human; 1:1000; fig 2c
  • western blot; mouse; 1:1000; loading ...; fig 2d
  • western blot; African green monkey; 1:1000; loading ...; fig 2c
Drelon C, Berthon A, Sahut Barnola I, Mathieu M, Dumontet T, Rodriguez S, et al. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. Nat Commun. 2016;7:12751 pubmed publisher
  • western blot; human
Grünberg J, Hammarstedt A, Hedjazifar S, Smith U. The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT. J Biol Chem. 2014;289:6899-907 pubmed publisher
Götzel K, Chemnitzer O, Maurer L, Dietrich A, Eichfeld U, Lyros O, et al. In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett's sequence. BMC Gastroenterol. 2019;19:38 pubmed publisher
product information
SKU :
5651S
Product-Name :
Phospho-β-Catenin (Ser552) (D8E11) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M, R, X, Z)
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
92
Host :
Rabbit
Target :
Catenin-beta (Ser552) phosphate
Primary-Protein :
CTNNB1
Alt-Names :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.