product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Presenilin 1 (D39D1) Rabbit mAb
catalog :
5643S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; fig s2
Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000
  • western blot; rat; 1:1000
Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed publisher
  • immunohistochemistry; rat
  • western blot; rat; 1:1000
Ashok A, Rai N, Tripathi S, Bandyopadhyay S. Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats. Toxicol Sci. 2015;143:64-80 pubmed publisher
  • western blot; human
Marinangeli C, Tasiaux B, Opsomer R, Hage S, Sodero A, Dewachter I, et al. Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex. J Biol Chem. 2015;290:7169-84 pubmed publisher
  • western blot; human
  • immunoprecipitation; human
Noss E, Watts G, Zocco D, Keller T, Whitman M, Blobel C, et al. Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis Res Ther. 2015;17:126 pubmed publisher
Ann E, Kim H, Seo M, Mo J, Kim M, Yoon J, et al. Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein. J Biol Chem. 2012;287:36814-29 pubmed publisher
product information
SKU :
5643S
Product-Name :
Presenilin 1 (D39D1) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
22 (CTF)
Host :
Rabbit
Target :
Presenilin-1
Primary-Protein :
PSEN1
Alt-Names :
AD3,FAD,PS-1,PS1,PS1-CTF12,PSEN1,PSN1,PSNL1,Presenilin-1,Presenilin-1 CTF subunit,Presenilin-1 CTF12,Presenilin-1 NTF subunit,Protein S182,S182,presenilin 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.