product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CD44 (8E2) Mouse mAb
catalog :
5640
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8E2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section, blocking or activating experiments
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; fig 6b
  • immunocytochemistry; human; loading ...; fig 1e
Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Patouraux S, Rousseau D, Bonnafous S, Lebeaupin C, Luci C, Canivet C, et al. CD44 is a key player in non-alcoholic steatohepatitis. J Hepatol. 2017;67:328-338 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 6
Li X, Wu J, Li Q, Shigemura K, Chung L, Huang W. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget. 2016;7:12869-84 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5C
Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed publisher
  • western blot; human; fig 1a,b
Yun J, Song S, Kang J, Park J, Kim H, Han S, et al. Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability. Nucleic Acids Res. 2016;44:558-72 pubmed publisher
  • immunocytochemistry; rat
Sawitza I, Kordes C, Götze S, Herebian D, Häussinger D. Bile acids induce hepatic differentiation of mesenchymal stem cells. Sci Rep. 2015;5:13320 pubmed publisher
  • blocking or activating experiments; mouse
Seo K, Lee S, Ye B, Kim Y, Bae S, Kim C. Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC. J Mol Cell Cardiol. 2015;85:13-24 pubmed publisher
  • western blot; human; 1:1000; fig 3
Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  • immunocytochemistry; human; 1:800
  • western blot; human
Costabile V, Duraturo F, Delrio P, Rega D, Pace U, Liccardo R, et al. Lithium chloride induces mesenchymal‑to‑epithelial reverting transition in primary colon cancer cell cultures. Int J Oncol. 2015;46:1913-23 pubmed publisher
  • immunohistochemistry - free floating section; human; 1:2000
Long P, Tighe S, Driscoll H, Fortner K, Viapiano M, Jaworski D. Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest. J Cell Physiol. 2015;230:1929-43 pubmed publisher
  • western blot; human; fig 2
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • western blot; human
Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
  • immunohistochemistry; human
Zhao J, Lin J, Zhu D, Wang X, Brooks D, Chen M, et al. miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/?-catenin/BCL9 pathway. Cancer Res. 2014;74:1801-13 pubmed publisher
Jia D, Li L, Andrew S, Allan D, Li X, Lee J, et al. An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells. Cell Death Dis. 2017;8:e2932 pubmed publisher
product information
SKU :
5640S
Product-Name :
CD44 (8E2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80
Host :
Mouse
Target :
CD44
Primary-Protein :
CD44
Alt-Names :
CD44,CD44 antigen,CD44 antigen (homing function and Indian blood group system),CD44 molecule (Indian blood group),CDW44 antigen,CDw44,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,HUTCH-I,Heparan sulfate proteoglycan,Hermes antigen,Hyaluronate receptor,IN,LHR,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH-I,PGP-1,PGP-I,Pgp1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,antigen gp90 homing receptor,cell adhesion molecule,cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,extracellular matrix receptor-III,hematopoietic cell E- and L-selectin ligand,homing function and Indian blood group system
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.