A20/TNFAIP3 (D13H3) Rabbit mAb | Cell Signaling Technology 5630 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

A20/TNFAIP3 (D13H3) Rabbit mAb

catalog :

5630

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D13H3

reactivity :

human, mouse

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 2c western blot; human; 1:1000; loading ...; fig 2c, 6a	Feng Y, Zhang Y, Cai Y, Liu R, Lu M, Li T, et al. A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma. Cell Death Dis. 2020;11:89 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5e	Seeholzer T, Kurz S, Schlauderer F, Woods S, Gehring T, Widmann S, et al. BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation. Front Immunol. 2018;9:2695 pubmed publisher
western blot; human; loading ...; fig 5f	Bi E, Li R, Bover L, Li H, Su P, Ma X, et al. E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. J Clin Invest. 2018;128:4821-4831 pubmed publisher
western blot; mouse; loading ...; fig 1b	Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2c western blot; mouse; 1:1000; fig 2c	Sokhi U, Liber M, Frye L, Park S, Kang K, Pannellini T, et al. Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nat Commun. 2018;9:658 pubmed publisher
western blot; human; loading ...; fig 1d	Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, et al. HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways. Oncotarget. 2016;7:33796-808 pubmed publisher
western blot; human; fig 1	Ai L, Xu Q, Wu C, Wang X, Chen Z, Su D, et al. A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis. Int J Biol Sci. 2015;11:1436-46 pubmed publisher
flow cytometry; human; loading ...; fig 4a	GuzmÃ¡n E, Maers K, Roberts J, Kemami Wangun H, Harmody D, Wright A. The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells. Invest New Drugs. 2015;33:86-94 pubmed publisher
	Kreckel J, Anany M, Siegmund D, Wajant H. TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling. Front Immunol. 2019;10:2024 pubmed publisher
	Lee I, Lim J, Cho H, Kim E, Kim Y, Oh H, et al. MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity. Mol Cell. 2019;73:1138-1149.e6 pubmed publisher
	Li Y, Mooney E, Holden S, Xia X, Cohen D, Walsh S, et al. A20 Orchestrates Inflammatory Response in the Oral Mucosa through Restraining NF-κB Activity. J Immunol. 2019;202:2044-2056 pubmed publisher
	Essig K, Kronbeck N, Guimaraes J, Lohs C, Schlundt A, Hoffmann A, et al. Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation. Nat Commun. 2018;9:3810 pubmed publisher
	Dalet A, Argüello R, Combes A, Spinelli L, Jaeger S, Fallet M, et al. Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA. EMBO J. 2017;36:761-782 pubmed publisher
	Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed publisher
	Shao L, Oshima S, Duong B, Advincula R, Barrera J, Malynn B, et al. A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS ONE. 2013;8:e62223 pubmed publisher
	Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, et al. Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-?B regulation. EMBO J. 2012;31:3856-70 pubmed publisher

product information

SKU :

5630S

Product-Name :

A20/TNFAIP3 (D13H3) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

TNFAIP3

Primary-Protein :

TNFAIP3

Alt-Names :

A20,MGC104522,MGC138687,MGC138688,OTU domain-containing protein 7C,OTUD7C,Putative DNA-binding protein A20,TNAP3,TNF alpha-induced protein 3,TNFA1P2,TNFAIP3,Tumor necrosis factor alpha-induced protein 3,Zinc finger protein A20,tumor necrosis factor inducible protein A20,tumor necrosis factor, alpha-induced protein 3

more info or order :

Cell Signaling Technology product webpage