| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1500; loading ...; fig 5j
| Xia R, Liu T, Li W, Xu X. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA. Clin Transl Med. 2021;11:e383 pubmed publisher |
- immunohistochemistry - paraffin section; human; fig 5c
| Zhang Z, Li X, Yang F, Chen C, Liu P, Ren Y, et al. DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis. Nat Commun. 2021;12:5872 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Gao C, Deng J, Zhang H, Li X, Gu S, Zheng M, et al. HSPA13 facilitates NF-κB-mediated transcription and attenuates cell death responses in TNFα signaling. Sci Adv. 2021;7:eabh1756 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1e, 1h
| Xue Y, Morris J, Yang K, Fu Z, Zhu X, Johnson F, et al. SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria. Nat Commun. 2021;12:5404 pubmed publisher |
- western blot; human; 1:1000; fig 5c
| Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed publisher |
- western blot; human; loading ...
| Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, et al. GRB2 enforces homology-directed repair initiation by MRE11. Sci Adv. 2021;7: pubmed publisher |
- western blot; human; loading ...; fig 3e, 3f
| Zhang Y, Ma Y, Wu G, Xie M, Luo C, Huang X, et al. SENP1 promotes MCL pathogenesis through regulating JAK-STAT5 pathway and SOCS2 expression. Cell Death Discov. 2021;7:192 pubmed publisher |
- immunohistochemistry; human; loading ...; fig s6g
- western blot; human; loading ...; fig 5d
| Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, et al. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation. Nat Commun. 2021;12:3651 pubmed publisher |
- western blot; human; loading ...; fig 7b
| Liu J, Hideshima T, Xing L, Wang S, Zhou W, Samur M, et al. ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment. Sci Adv. 2021;7: pubmed publisher |
- western blot; human; 1:2000; fig 2e
| Ray U, Roy D, Jin L, Thirusangu P, Staub J, Xiao Y, et al. Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization. J Exp Clin Cancer Res. 2021;40:182 pubmed publisher |
- western blot; human; loading ...; fig 3f, 4e
| Ma X, Zhao T, Yan H, Guo K, Liu Z, Wei L, et al. Fatostatin reverses progesterone resistance by inhibiting the SREBP1-NF-κB pathway in endometrial carcinoma. Cell Death Dis. 2021;12:544 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1i
| Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella J, et al. Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia. Nat Commun. 2021;12:2482 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3f
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- immunohistochemistry; human; 1:400; loading ...; fig s4a
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- western blot; human; fig 2f
| Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed publisher |
- western blot; mouse; loading ...; fig 4h
- western blot; human; 1:1000; loading ...; fig 4g
| Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5g
| Wei Y, Jiang Z, Lu J. USP22 promotes melanoma and BRAF inhibitor resistance via YAP stabilization. Oncol Lett. 2021;21:394 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Xiong M, Wu M, Dan Peng -, Huang W, Chen Z, Ke H, et al. LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells. Cell Death Dis. 2021;12:24 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Huang H, Yu X, Han X, Hao J, Zhao J, Bebek G, et al. Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression. Cell Rep. 2021;34:108522 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3d
| Zhang J, Huang J, Zhang Y, Zhang X, Zhao L, Li C, et al. Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3. EBioMedicine. 2020;53:102701 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2f
| Wan G, An Y, Tao J, Wang Y, Zhou Q, Yang R, et al. MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway. Biosci Rep. 2020;40: pubmed publisher |
- western blot; human; loading ...; fig 3d
| Qiao H, Tan X, Lv D, Xing R, Shu F, Zhong C, et al. Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis. J Cancer. 2020;11:1027-1037 pubmed publisher |
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- immunohistochemistry - paraffin section; human; loading ...; fig 7h
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- western blot; human; loading ...; fig 4f
| Pan C, Jin L, Wang X, Li Y, Chun J, Boese A, et al. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest. 2019;129:2431-2445 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 6a
- western blot; human; loading ...; fig 6a
| Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4d
| Singh R, Peng S, Viswanath P, Sambandam V, Shen L, Rao X, et al. Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis. EMBO Mol Med. 2019;: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3a
| Poondla N, Chandrasekaran A, Heese K, Kim K, Ramakrishna S. CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis. Biochem Biophys Res Commun. 2019;: pubmed publisher |
- western blot; human; loading ...; fig 4c
| Yan M, Wang J, Ren Y, Li L, He W, Zhang Y, et al. Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization. Cell Death Dis. 2019;10:204 pubmed publisher |
- western blot; human; loading ...; fig s1a
| Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher |
- western blot; human; loading ...; fig 8f
| Yambire K, Fernández Mosquera L, Steinfeld R, Mühle C, Ikonen E, Milosevic I, et al. Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 4c
| Dufour F, Silina L, Neyret Kahn H, Moreno Vega A, Krucker C, Karboul N, et al. TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer. Br J Cancer. 2019;120:555-564 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a, 4b, 4c
| Asnaghi L, White D, Key N, Choi J, Mahale A, Alkatan H, et al. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2019;38:2056-2075 pubmed publisher |
- western blot; mouse; loading ...; fig 4c
| Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2019;453:187-196 pubmed publisher |
- western blot; human; loading ...; fig 2g
| Lee E, Ouzounova M, Piranlioglu R, Ma M, Guzel M, Marasco D, et al. The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20. Oncogene. 2019;38:469-482 pubmed publisher |
- western blot; human; loading ...; fig 3s1c
| Unni A, Harbourne B, Oh M, Wild S, Ferrarone J, Lockwood W, et al. Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells. elife. 2018;7: pubmed publisher |
- western blot; human; loading ...; fig s15a
| Zhao D, Kim Y, Jeong S, Greenson J, Chaudhry M, Hoepting M, et al. Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease. J Clin Invest. 2018;128:4970-4979 pubmed publisher |
- western blot; human; loading ...; fig s7b
| Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed publisher |
- western blot; human; loading ...; fig 8b
| Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed publisher |
- western blot; human; fig 2e
| Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed publisher |
- western blot; human; fig 5h
| Viswanath P, Radoul M, Izquierdo Garcia J, Ong W, Luchman H, Cairncross J, et al. 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. Cancer Res. 2018;78:2290-2304 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Sorokina I, Denisenko T, Imreh G, Tyurin Kuzmin P, Kaminskyy V, Gogvadze V, et al. Involvement of autophagy in the outcome of mitotic catastrophe. Sci Rep. 2017;7:14571 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Zhao Z, Jia Q, Wu M, Xie X, Wang Y, Song G, et al. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018;24:130-144 pubmed publisher |
- western blot; human; loading ...; fig s9b
| Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher |
- immunocytochemistry; human; 1:400; loading ...; fig s5b
| Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher |
- western blot; human; loading ...; fig 9a
| Wang W, Xia Z, Farré J, Subramani S. TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import. J Cell Biol. 2017;216:2843-2858 pubmed publisher |
- western blot; human; loading ...; fig 4i
| Xu L, Zhang M, Li H, Guan W, Liu B, Liu F, et al. SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. Leuk Lymphoma. 2018;59:918-930 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5a
| Xu P, Tao X, Zhao C, Huang Q, Chang H, Ban N, et al. DTX3L is upregulated in glioma and is associated with glioma progression. Int J Mol Med. 2017;40:491-498 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, et al. PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth. Nature. 2017;546:554-558 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2b
| Ramírez Peinado S, Ignashkova T, van Raam B, Baumann J, Sennott E, Gendarme M, et al. TRAPPC13 modulates autophagy and the response to Golgi stress. J Cell Sci. 2017;130:2251-2265 pubmed publisher |
- western blot; human; loading ...; fig s6a
| White M, Lin C, Rajapakshe K, Dong J, Shi Y, Tsouko E, et al. Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer. Mol Cancer Res. 2017;15:1017-1028 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5e
| Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher |
- western blot; human; loading ...; fig 2d
| He M, Tan B, Vasan K, Yuan H, Cheng F, Ramos da Silva S, et al. SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells. J Pathol. 2017;242:309-321 pubmed publisher |
- immunohistochemistry; human; 1:50; loading ...; fig 7
| Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7c
| Yokoyama T, Kohn E, Brill E, Lee J. Apoptosis is augmented in high-grade serous ovarian cancer by the combined inhibition of Bcl-2/Bcl-xL and PARP. Int J Oncol. 2017;: pubmed publisher |
- western blot; mouse; 1:500; fig 6a
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- western blot; human; loading ...; fig 1f
| Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, et al. DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin. Cancer Lett. 2017;400:194-202 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6b
| Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher |
- flow cytometry; human; 1:800; fig s1
| Sizdahkhani S, Feldman M, Piazza M, Ksendzovsky A, Edwards N, Ray Chaudhury A, et al. Somatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target. Sci Rep. 2017;7:40822 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Damas N, Marcatti M, Come C, Christensen L, Nielsen M, Baumgartner R, et al. SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. Nat Commun. 2016;7:13875 pubmed publisher |
- immunocytochemistry; human; loading ...; fig s2
| Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2c
| Morishita M, Kawamoto T, Hara H, Onishi Y, Ueha T, Minoda M, et al. AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway. Int J Oncol. 2017;50:23-30 pubmed publisher |
- western blot; human; loading ...; fig 3h
| Godfrey L, Kerry J, Thorne R, Repapi E, Davies J, Tapia M, et al. MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27Â acetylation. Exp Hematol. 2017;47:64-75 pubmed publisher |
- western blot; human; fig 3c
| Park J, Lee C, Kim H, Kim D, Son J, Ko E, et al. Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling. Oncotarget. 2016;7:83308-83318 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher |
- western blot; human; 1:800; loading ...; fig 2a
| Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, et al. Targeting Notch signaling as a novel therapy for retinoblastoma. Oncotarget. 2016;7:70028-70044 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Bahr J, Robey R, Luchenko V, Basseville A, Chakraborty A, Kozlowski H, et al. Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. Oncotarget. 2016;7:69804-69815 pubmed publisher |
- western blot; human; loading ...; fig 6a
| Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, et al. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. 2016;7:56338-56354 pubmed publisher |
- western blot; human; fig 2
| Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher |
- western blot; human; 1:1000; fig 3
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- western blot; human; loading ...; fig 3c
| Ono H, Basson M, Ito H. P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer. Oncotarget. 2016;7:51301-51310 pubmed publisher |
- western blot; human; loading ...; fig 7b
| Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. 2016;7:42274-42287 pubmed publisher |
- immunocytochemistry; human; fig 1
- immunohistochemistry; human; fig 1
- western blot; human; fig 1
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- western blot; human; loading ...; fig 1b
| Nakajima W, Sharma K, Lee J, Maxim N, Hicks M, Vu T, et al. DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex. Oncotarget. 2016;7:36353-36365 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 2b
| Matsushita R, Yoshino H, Enokida H, Goto Y, Miyamoto K, Yonemori M, et al. Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): Inhibition of bladder cancer cell aggressiveness. Oncotarget. 2016;7:28460-87 pubmed publisher |
- western blot; human; loading ...; fig 5e
| Slørdahl T, Abdollahi P, Vandsemb E, Rampa C, Misund K, Baranowska K, et al. The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells. Oncotarget. 2016;7:27295-306 pubmed publisher |
- immunohistochemistry - paraffin section; human; fig 5
- western blot; human; fig 5
| Lian Y, Yuan J, Cui Q, Feng Q, Xu M, Bei J, et al. Upregulation of KLHDC4 Predicts a Poor Prognosis in Human Nasopharyngeal Carcinoma. PLoS ONE. 2016;11:e0152820 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. Biochem Biophys Res Commun. 2016;473:490-6 pubmed publisher |
- western blot; human; loading ...; fig 2d
| Gari H, Gearheart C, Fosmire S, Degala G, Fan Z, Torkko K, et al. Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers. Oncotarget. 2016;7:15757-71 pubmed publisher |
- immunocytochemistry; human; 1:1000; fig 4
| Chen N, Uddin B, Voit R, Schiebel E. Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion. Proc Natl Acad Sci U S A. 2016;113:990-5 pubmed publisher |
- western blot; human; 1:1000; fig 5
| Amato K, Wang S, Tan L, Hastings A, Song W, Lovly C, et al. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res. 2016;76:305-18 pubmed publisher |
- western blot; human; 1:1000; fig s5
| Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed publisher |
- western blot; human; fig 2
| Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, et al. Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma. Oncotarget. 2016;7:1717-31 pubmed publisher |
- western blot; human; loading ...; fig 3
| Nakajima W, Sharma K, Hicks M, Le N, Brown R, Krystal G, et al. Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer. Cancer Biol Ther. 2016;17:27-35 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2c
| Momcilovic M, McMickle R, Abt E, Seki A, Simko S, Magyar C, et al. Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers. Cancer Res. 2015;75:4910-22 pubmed publisher |
- western blot; human; loading ...; fig 2e
| Li K, Gao B, Li J, Chen H, Li Y, Wei Y, et al. ZNF32 protects against oxidative stress-induced apoptosis by modulating C1QBP transcription. Oncotarget. 2015;6:38107-26 pubmed publisher |
- western blot; human; loading ...; fig 3c
| Mazzacurati L, Lambert Q, Pradhan A, Griner L, Huszar D, Reuther G. The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells. Oncotarget. 2015;6:40141-57 pubmed publisher |
- western blot; human; fig 1
| Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R. The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1. Sci Rep. 2015;5:14798 pubmed publisher |
- western blot; human; fig 5a
| Inaguma S, Ito H, Riku M, Ikeda H, Kasai K. Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 2015;6:28257-68 pubmed publisher |
- western blot; human; fig 5
| Hamacher Brady A, Brady N. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation. J Biol Chem. 2015;290:22005-18 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Dettmer U, Newman A, Soldner F, Luth E, Kim N, von Saucken V, et al. Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation. Nat Commun. 2015;6:7314 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher |
- immunohistochemistry - paraffin section; human; fig 4
- western blot; human; fig 3
| Qiu J, Zhang Y, Li Y, Zhao J, Zhang W, Jiang Q, et al. Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter. Oncotarget. 2015;6:15494-509 pubmed |
- western blot; human; fig f4
| Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed |
- western blot; human; fig 8c
| Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5c
| Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3c
- western blot; mouse; 1:1000; loading ...; fig 5c
| Ma W, Na M, Tang C, Wang H, Lin Z. Overexpression of N-myc downstream-regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT pathways. Mol Med Rep. 2015;12:1050-8 pubmed publisher |
| Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed publisher |
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