product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb
catalog :
5621S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Emmerich C, Bakshi S, Kelsall I, Ortiz-Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-61 pubmed publisher
  • western blot; human; fig 3, 4, 5
Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed publisher
  • western blot; human; fig 3b
Hochrainer K, Pejanovic N, Olaseun V, Zhang S, Iadecola C, Anrather J. The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Nucleic Acids Res. 2015;43:9889-904 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed publisher
  • western blot; mouse; 1:1000
Kanayama M, Inoue M, Danzaki K, Hammer G, He Y, Shinohara M. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nat Commun. 2015;6:5779 pubmed publisher
  • western blot; mouse
Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis. Toxicology. 2014;322:43-50 pubmed publisher
  • western blot; mouse; 1:1,000
Shiba-Fukushima K, Inoshita T, Hattori N, Imai Y. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J Biol Chem. 2014;289:33131-6 pubmed publisher
Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, Estiu G, Stahelin R, et al. A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature. 2015;520:683-7 pubmed publisher
Blessing N, Brockman A, Chadee D. The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3. Mol Cell Biol. 2014;34:3132-43 pubmed publisher
Chen C, Meng Y, Wang L, Wang H, Tian C, Pang G, et al. Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways. Immunology. 2014;142:307-19 pubmed publisher
Zhang J, Ma W, Tian S, Fan Z, Ma X, Yang X, et al. RanBPM interacts with TβRI, TRAF6 and curbs TGF induced nuclear accumulation of TβRI. Cell Signal. 2014;26:162-72 pubmed publisher
Hooper C, Jackson S, Coughlin E, Coon J, Miyamoto S. Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro. J Biol Chem. 2014;289:33161-74 pubmed publisher
Liu N, Li X, Huang H, Zhao C, Liao S, Yang C, et al. Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth. Oncotarget. 2014;5:5453-71 pubmed
product information
SKU :
5621S
Product-Name :
K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
All
Applications :
Western blot
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Ubiquitin poly Lys63
Primary-Protein :
ubiquitin
Alt-Names :
40S ribosomal protein S27a,CEP80,RPS27A,Ribosomal protein S27a,UBA52,UBA80,UBB,UBC,UBCEP1,UBCEP80,UBIQ,ubiquitin and ribosomal protein S27a,ubiquitin carboxyl extension protein 80,ubiquitin-CEP80
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.