product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Myc (D84C12) XP® Rabbit mAb
catalog :
5605S
quantity :
100 ul
price :
260 USD
clonality :
monoclonal
host :
rabbit
reactivity :
, human, mouse, rat, dog, pig, rabbit
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 7a
Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2015;: pubmed publisher
  • western blot; rat; 1:1000; fig 6
Prause M, Mayer C, Brorsson C, Frederiksen K, Billestrup N, Størling J, et al. JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression. J Diabetes Res. 2016;2016:1312705 pubmed publisher
  • western blot; human; 1:1000; fig 2
Chen Y, Zhou C, Ji W, Mei Z, Hu B, Zhang W, et al. ELL targets c-Myc for proteasomal degradation and suppresses tumour growth. Nat Commun. 2016;7:11057 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 4
Farrugia A, Calvo F. Cdc42 regulates Cdc42EP3 function in Cancer-Associated Fibroblasts. Small Gtpases. 2016;: pubmed
  • immunocytochemistry; pig; fig 2
Zhang Y, Ma J, Li H, Lv J, Wei R, Cong Y, et al. bFGF signaling-mediated reprogramming of porcine primordial germ cells. Cell Tissue Res. 2016;364:429-41 pubmed publisher
  • western blot; human; 1:1000; fig 3
Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of β-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  • western blot; human; fig 2
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • western blot; mouse
Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher
  • western blot; human; 1:1000; fig 4b
Birket M, Ribeiro M, Verkerk A, Ward D, Leitoguinho A, Den Hartogh S, et al. Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells. Nat Biotechnol. 2015;33:970-9 pubmed publisher
  • western blot; human; fig f4
Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
  • western blot; human; fig 5
Liu L, Zhang J, Yang X, Fang C, Xu H, Xi X. SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer. PLoS ONE. 2015;10:e0138515 pubmed publisher
  • western blot; human; fig 6c
Li A, Jiao Y, Yong K, Wang F, Gao C, Yan B, et al. SALL4 is a new target in endometrial cancer. Oncogene. 2015;34:63-72 pubmed publisher
  • western blot; rabbit; 1:500; fig 3
Li P, Zhang L. Exogenous Nkx2.5- or GATA-4-transfected rabbit bone marrow mesenchymal stem cells and myocardial cell co-culture on the treatment of myocardial infarction in rabbits. Mol Med Rep. 2015;12:2607-21 pubmed publisher
  • western blot; human
  • immunoprecipitation; human
Zhang Q, Yang Z, Wang W, Guo T, Jia Z, Ma K, et al. A positive feedback regulation of ISL-1 in DLBCL but not in pancreatic β-cells. Biochem Biophys Res Commun. 2014;449:295-300 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
Lin Q, Aihara A, Chung W, Li Y, Chen X, Huang Z, et al. LRH1 promotes pancreatic cancer metastasis. Cancer Lett. 2014;350:15-24 pubmed publisher
  • western blot; human
Florea V, Bhagavatula N, Simovic G, Macedo F, Fock R, Rodrigues C. c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype. PLoS ONE. 2013;8:e73146 pubmed publisher
Fogal V, Babic I, Chao Y, Pastorino S, Mukthavaram R, Jiang P, et al. Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction. Oncotarget. 2015;6:1157-70 pubmed
Satelli A, Mitra A, Brownlee Z, Xia X, Bellister S, Overman M, et al. Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression. Clin Cancer Res. 2015;21:899-906 pubmed publisher
Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
Cheng Q, Yuan F, Lu F, Zhang B, Chen T, Chen X, et al. CSIG promotes hepatocellular carcinoma proliferation by activating c-MYC expression. Oncotarget. 2015;6:4733-44 pubmed
Moros A, Rodriguez V, Saborit-Villarroya I, Montraveta A, Balsas P, Sandy P, et al. Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma. Leukemia. 2014;28:2049-59 pubmed publisher
Zhang Z, Kim K, Li X, Moreno M, Sharp T, Goodheart M, et al. MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression. Mol Cancer Ther. 2014;13:1942-51 pubmed publisher
Hatano K, Yamaguchi S, Nimura K, Murakami K, Nagahara A, Fujita K, et al. Residual prostate cancer cells after docetaxel therapy increase the tumorigenic potential via constitutive signaling of CXCR4, ERK1/2 and c-Myc. Mol Cancer Res. 2013;11:1088-100 pubmed publisher
Popkie A, Zeidner L, Albrecht A, D'Ippolito A, Eckardt S, Newsom D, et al. Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. J Biol Chem. 2010;285:41337-47 pubmed publisher
Veronese A, Visone R, Consiglio J, Acunzo M, Lupini L, Kim T, et al. Mutated beta-catenin evades a microRNA-dependent regulatory loop. Proc Natl Acad Sci U S A. 2011;108:4840-5 pubmed publisher
product information
SKU :
5605S
Product-Name :
c-Myc (D84C12) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, (Mk, Dg, Pg)
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
57-65
Host :
Rabbit
Target :
Myc
Primary-Protein :
Myc
Alt-Names :
BHLHE39,Class E basic helix-loop-helix protein 39,MRTL,MYC,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64,avian myelocytomatosis viral oncogene homolog,c-Myc,myc-related translation/localization regulatory factor,v-myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.