product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Tyro3 (D38C6) Rabbit mAb
catalog :
5585
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D38C6
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, other
citations: 6
Published Application/Species/Sample/DilutionReference
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 1a
Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  • western blot; mouse; fig 1
Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher
Lee Sherick A, Zhang W, Menachof K, Hill A, Rinella S, Kirkpatrick G, et al. Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia. Oncotarget. 2015;6:6722-36 pubmed
Migdall Wilson J, Bates C, Schlegel J, BRANDAO L, Linger R, DeRyckere D, et al. Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus. PLoS ONE. 2012;7:e31635 pubmed publisher
product information
SKU :
5585S
Product-Name :
Tyro3 (D38C6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110, 130
Host :
Rabbit
Target :
Tyro3
Primary-Protein :
Tyro3
Alt-Names :
BYK,Brt,DTK,FLJ16467,RSE,SKY,TYRO3,TYRO3 protein tyrosine kinase,Tif,Tyro3 protein tyrosine kinase (sea-related receptor tyrosine kinase),Tyrosine-protein kinase DTK,Tyrosine-protein kinase RSE,Tyrosine-protein kinase SKY,Tyrosine-protein kinase byk,Tyrosine-protein kinase receptor TYRO3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.