product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-GSK-3β (Ser9) (D85E12) XP® Rabbit mAb
catalog :
5558S
quantity :
100 ul
price :
301 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 11
Published Application/Species/DilutionReference
  • western blot; mouse
Williams J, Ni H, Haynes A, Manley S, Li Y, Jaeschke H, et al. Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice. J Biol Chem. 2015;290:10934-46 pubmed publisher
  • western blot; human; fig 1
Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
  • western blot; mouse
Manley S, Ni H, Williams J, Kong B, DiTacchio L, Guo G, et al. Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity. Redox Biol. 2014;2:991-1002 pubmed publisher
  • flow cytometry; mouse
McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
  • western blot; human; fig 6
Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, et al. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat Commun. 2014;5:3393 pubmed publisher
  • western blot; human
BENTLEY C, Jurinka S, Kljavin N, Vartanian S, Ramani S, Gonzalez L, et al. A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation. Biochem J. 2013;452:313-20 pubmed publisher
Mudireddy S, Abdul A, Gorjala P, Gary R. Beryllium is an inhibitor of cellular GSK-3β that is 1,000-fold more potent than lithium. Biometals. 2014;27:1203-16 pubmed publisher
Deng H, Zhang X, Wang M, Zheng H, Liu L, Wang Z. ER-α36-mediated rapid estrogen signaling positively regulates ER-positive breast cancer stem/progenitor cells. PLoS ONE. 2014;9:e88034 pubmed publisher
Fedorchenko O, Stiefelhagen M, Peer-Zada A, Barthel R, Mayer P, Eckei L, et al. CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. 2013;121:4126-36 pubmed publisher
Ikushima Y, Arai F, Hosokawa K, Toyama H, Takubo K, Furuyashiki T, et al. Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells. Blood. 2013;121:1995-2007 pubmed publisher
Mirlashari M, Randen I, Kjeldsen-Kragh J. Glycogen synthase kinase-3 (GSK-3) inhibition induces apoptosis in leukemic cells through mitochondria-dependent pathway. Leuk Res. 2012;36:499-508 pubmed publisher
product information
SKU :
5558S
Product-Name :
Phospho-GSK-3β (Ser9) (D85E12) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
301 USD
Species-x-Reactivity :
H, M, R, Hm
Applications :
Flow cytometry
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
46
Host :
Rabbit
Target :
GSK3-beta (Ser9) phosphate
Primary-Protein :
GSK3B
Alt-Names :
GSK-3 beta,GSK3B,GSK3beta isoform,Glycogen synthase kinase-3 beta,glycogen synthase kinase 3 beta
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.