product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Ubiquityl-Histone H2B (Lys120) (D11) XP® Rabbit mAb
catalog :
5546
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D11
reactivity :
Saccharomycetales, human, mouse, rat, brewer's yeast
application :
western blot, immunoprecipitation, chromatin immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Kosinsky R, Saul D, Ammer Herrmenau C, Faubion W, Neesse A, Johnsen S. USP22 Suppresses SPARC Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; brewer's yeast; loading ...; fig 5s1a
Donczew R, Warfield L, Pacheco D, Erijman A, Hahn S. Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA. elife. 2020;9: pubmed publisher
  • western blot; mouse; fig 1b
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher
  • western blot; human; fig 6g
Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, et al. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015;35:3633-45 pubmed publisher
  • western blot; human; fig 5
Chen F, Woodfin A, Gardini A, Rickels R, Marshall S, Smith E, et al. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. 2015;162:1003-15 pubmed publisher
  • western blot; rat; 1:2000
Gagnon J, Daou S, Zamorano N, Iannantuono N, Hammond Martel I, Mashtalir N, et al. Undetectable histone O-GlcNAcylation in mammalian cells. Epigenetics. 2015;10:677-91 pubmed publisher
  • western blot; human
Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed publisher
  • chromatin immunoprecipitation; Saccharomycetales
Bonizec M, Hérissant L, Pokrzywa W, Geng F, Wenzel S, Howard G, et al. The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B. Nucleic Acids Res. 2014;42:10975-86 pubmed publisher
  • western blot; human
Ji X, Lu H, Zhou Q, Luo K. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. elife. 2014;3:e02907 pubmed publisher
  • chromatin immunoprecipitation; human; fig 3
Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, et al. Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription. Cell Rep. 2014;8:460-9 pubmed publisher
  • western blot; human; fig 3
Bedi U, Scheel A, Hennion M, Begus Nahrmann Y, Ruschoff J, Johnsen S. SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms. Oncogene. 2015;34:465-73 pubmed publisher
Dong Y, Isono K, Ohbo K, Endo T, Ohara O, Maekawa M, et al. EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice. Mol Cell Biol. 2017;37: pubmed publisher
Basnet H, Su X, Tan Y, Meisenhelder J, Merkurjev D, Ohgi K, et al. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014;516:267-71 pubmed publisher
product information
SKU :
5546P
Product-Name :
Ubiquityl-Histone H2B (Lys120) (D11) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
H2B (Lys121) ubiquitinate
Primary-Protein :
H2B
Alt-Names :
H2B histone family, member F,H2B.1,H2B/f,H2B1B,H2BFF,HIST1H2BB,Histone H2B type 1-B,Histone H2B.1,Histone H2B.f,MGC119804,histone 1, H2bb,histone cluster 1, H2bb
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.