Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb | Cell Signaling Technology 5483S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb

catalog :

5483S

quantity :

100 ul

price :

301 USD

clonality :

monoclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

African green monkey, human, mouse, rat, dog, cow

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, other

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Dilution	Reference
western blot (knockdown validation); human; fig s2	Zhang G, Chan B, Samarina N, Abere B, Weidner-Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed publisher
western blot; human; fig 3	Richter B, Sliter D, Herhaus L, Stolz A, Wang C, Beli P, et al. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proc Natl Acad Sci U S A. 2016;113:4039-44 pubmed publisher
western blot; mouse; fig 4c	Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
other; African green monkey; 1:50; fig 1 immunocytochemistry; African green monkey; 1:100; fig 1 immunocytochemistry; mouse; 1:100; fig s4 western blot; African green monkey; 1:1000; fig 1 western blot; mouse; 1:1000; fig 3	Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
western blot; mouse; fig 1a	Anghelina D, Lam E, Falck-Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
western blot; human	Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed publisher
western blot; human; fig 4 western blot; mouse; fig 4	Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen G, et al. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog. 2015;11:e1004779 pubmed publisher
western blot; human; fig 4 western blot; mouse; fig 4	Khan K, Dô F, Marineau A, Doyon P, Clément J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
western blot; mouse; fig 4	West A, Khoury-Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
	Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed publisher

product information

SKU :

5483S

Product-Name :

Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb

Size :

100 ul

Price-(USD) :

301 USD

Species-x-Reactivity :

H, (M, R, Mk, X, B, Dg)

Applications :

Flow cytometry

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

TBK1 (Ser172) phosphate

Primary-Protein :

TBK1

Alt-Names :

FLJ11330,NAK,NF-kB-activating kinase,NF-kappa-B-activating kinase,Serine/threonine-protein kinase TBK1,T2K,TANK-binding kinase 1,TBK1

more info or order :

Cell Signaling Technology product webpage