Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb | Cell Signaling Technology 5483P product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb

catalog :

5483P

quantity :

40 ul

price :

135 USD

clonality :

monoclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

African green monkey, human, mouse, rat, dog, cow

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, other

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Dilution	Reference
western blot; mouse; fig 1a	Anghelina D, Lam E, Falck-Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
western blot; human; fig 3	Richter B, Sliter D, Herhaus L, Stolz A, Wang C, Beli P, et al. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proc Natl Acad Sci U S A. 2016;113:4039-44 pubmed publisher
western blot; human; fig 4	Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
other; African green monkey; 1:50; fig 1 western blot; African green monkey; 1:1000; fig 1 western blot; mouse; 1:1000; fig 3 immunocytochemistry; African green monkey; 1:100; fig 1 immunocytochemistry; mouse; 1:100; fig s4	Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
western blot; human; 1:2000; fig 5 western blot; mouse; 1:2000; fig 5 immunocytochemistry; human; 1:250; fig 2 immunocytochemistry; mouse; 1:250; fig 3	Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher
western blot; mouse; fig 4	West A, Khoury-Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
western blot; mouse; fig 1	Malik N, Vollmer S, Nanda S, López-Peláez M, Prescott A, Gray N, et al. Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members. Biochem J. 2015;468:363-72 pubmed publisher
western blot; human; fig 4 western blot; mouse; fig 4	Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen G, et al. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog. 2015;11:e1004779 pubmed publisher
western blot; human; fig 4 western blot; mouse; fig 4	Khan K, Dô F, Marineau A, Doyon P, Clément J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
western blot; human	Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed publisher
immunoprecipitation; human immunoprecipitation; mouse western blot; human western blot; mouse immunocytochemistry; human immunocytochemistry; mouse	Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed publisher

product information

SKU :

5483P

Product-Name :

Phospho-TBK1/NAK (Ser172) (D52C2) XP® Rabbit mAb

Size :

40 ul

Price-(USD) :

135 USD

Species-x-Reactivity :

H, (M, R, Mk, X, B, Dg)

Applications :

Flow cytometry

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

TBK1 (Ser172) phosphate

Primary-Protein :

TBK1

Alt-Names :

FLJ11330,NAK,NF-kB-activating kinase,NF-kappa-B-activating kinase,Serine/threonine-protein kinase TBK1,T2K,TANK-binding kinase 1,TBK1

more info or order :

Cell Signaling Technology product webpage