product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FoxM1 (D12D5) XP® Rabbit mAb
catalog :
5436
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D12D5
reactivity :
human, mouse
application :
western blot, immunocytochemistry, reverse phase protein lysate microarray, other
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig s1e
Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 11a
Barger C, Chee L, Albahrani M, Munoz Trujillo C, Boghean L, Branick C, et al. Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer. elife. 2021;10: pubmed publisher
  • western blot; human; loading ...; fig 6e
Tang B, Sun R, Wang D, Sheng H, Wei T, Wang L, et al. ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • western blot; mouse; fig 7i
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
  • western blot; human; loading ...; fig 4b
Dufour F, Silina L, Neyret Kahn H, Moreno Vega A, Krucker C, Karboul N, et al. TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer. Br J Cancer. 2019;120:555-564 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 6e
Tanaka N, Zhao M, Tang L, Patel A, Xi Q, Van H, et al. Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1. Oncogene. 2018;37:1279-1292 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  • western blot; human; loading ...
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5b
Maachani U, Shankavaram U, Kramp T, Tofilon P, Camphausen K, Tandle A. FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells. Oncotarget. 2016;7:77365-77377 pubmed publisher
  • western blot; human; loading ...; fig 5c
Han S, Ma X, Zhao Y, Zhao H, Batista A, Zhou S, et al. Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer. Oncotarget. 2016;7:44406-44416 pubmed publisher
  • western blot; human; 1:2000; fig 4
Lin S, Kao C, Lee H, Creighton C, Ittmann M, Tsai S, et al. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016;7:11418 pubmed publisher
Qu S, Ci X, Xue H, Dong X, Hao J, Lin D, et al. Treatment with docetaxel in combination with Aneustat leads to potent inhibition of metastasis in a patient-derived xenograft model of advanced prostate cancer. Br J Cancer. 2018;118:802-812 pubmed publisher
Iwahori S, Kalejta R. Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus. Virology. 2017;512:95-103 pubmed publisher
Tanaka N, Patel A, Tang L, Silver N, Lindemann A, Takahashi H, et al. Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation. Clin Cancer Res. 2017;23:6541-6554 pubmed publisher
Fan Q, Cai Q, Xu Y. FOXM1 is a downstream target of LPA and YAP oncogenic signaling pathways in high grade serous ovarian cancer. Oncotarget. 2015;6:27688-99 pubmed publisher
Shimada Y, Katsube K, Kabasawa Y, Morita K, Omura K, Yamaguchi A, et al. Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features. PLoS ONE. 2013;8:e70995 pubmed publisher
product information
SKU :
5436P
Product-Name :
FoxM1 (D12D5) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Rabbit
Target :
FOXM1
Primary-Protein :
FOXM1
Alt-Names :
FKHL16,FOXM1,FOXM1B,Forkhead box protein M1,Forkhead, drosophila, homolog-like 16,Forkhead-related protein FKHL16,HFH-11,HFH11,HNF-3,HNF-3/fork-head homolog 11,Hepatocyte nuclear factor 3 forkhead homolog 11,INS-1,M-phase phosphoprotein 2,MPHOSPH2,MPM-2 reactive phosphoprotein 2,MPP-2,MPP2,PIG29,TGT3,TRIDENT,Transcription factor Trident,WIN,Winged-helix factor from INS-1 cells,forkhead box M1,forkhead-like 16
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.