product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SirT7 (D3K5A) Rabbit mAb
catalog :
5360
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D3K5A
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1c
  • western blot knockout validation; mouse; loading ...; fig 1a
  • western blot; rat; loading ...; fig 5a
Miyasato Y, Yoshizawa T, Sato Y, Nakagawa T, Miyasato Y, Kakizoe Y, et al. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response. Sci Rep. 2018;8:5927 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 5i
Li Z, Bridges B, Olson J, Weinman S. The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3. Oncogene. 2017;36:1887-1898 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1a
Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  • western blot; human; 1:250
Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett. 2015;233:227-38 pubmed publisher
Zhao J, Wozniak A, Adams A, Cox J, Vittal A, Voss J, et al. SIRT7 regulates hepatocellular carcinoma response to therapy by altering the p53-dependent cell death pathway. J Exp Clin Cancer Res. 2019;38:252 pubmed publisher
Chen G, Zhang B, Xu H, Sun Y, Shi Y, Luo Y, et al. Suppression of Sirt1 sensitizes lung cancer cells to WEE1 inhibitor MK-1775-induced DNA damage and apoptosis. Oncogene. 2017;36:6863-6872 pubmed publisher
product information
SKU :
5360S
Product-Name :
SirT7 (D3K5A) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
45
Host :
Rabbit
Target :
SirT7
Primary-Protein :
SIRT7
Alt-Names :
MGC126840,MGC126842,NAD-dependent deacetylase sirtuin-7,SIR2-like protein 7,SIR2L7,SIRT7,silent mating type information regulation 2, S.cerevisiae, homolog 7,sir2-related protein type 7,sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae),sirtuin type 7
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.