product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HDAC1 (10E2) Mouse mAb
catalog :
5356S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
10E2

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, RNA immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 15
Published Application/Species/DilutionReference
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; fig s3
G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 3
Vishwakarma B, Nguyen N, Makishima H, Hosono N, Gudmundsson K, Negi V, et al. Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development. Leukemia. 2016;30:200-8 pubmed publisher
  • western blot; human; fig 7
Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ERα dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  • western blot; mouse; fig 1d
Watanabe M, Takahashi H, Saeki Y, Ozaki T, Itoh S, Suzuki M, et al. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. elife. 2015;4:e05615 pubmed publisher
  • western blot; human; 1:1000; fig 5
Pickard A, McDade S, McFarland M, McCluggage W, Wheeler C, McCance D. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures. PLoS Pathog. 2015;11:e1004988 pubmed publisher
  • chromatin immunoprecipitation; rat; fig  6
  • western blot; rat; 1:1000; fig 8
Formisano L, Guida N, Valsecchi V, Cantile M, Cuomo O, Vinciguerra A, et al. Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism. J Neurosci. 2015;35:7332-48 pubmed publisher
  • western blot; human; 1:1000; fig s5
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Eisses J, Criscimanna A, Dionise Z, Orabi A, Javed T, Sarwar S, et al. Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. Am J Pathol. 2015;185:3304-15 pubmed publisher
  • western blot; rat
Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed publisher
  • western blot; human; fig 6
Bots M, Verbrugge I, Martin B, Salmon J, Ghisi M, Baker A, et al. Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. 2014;123:1341-52 pubmed publisher
  • western blot; mouse; 1:1000
Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher
Wu Q, Nie J, Gao Y, Xu P, Sun Q, Yang J, et al. Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1. Sci Rep. 2015;5:16355 pubmed publisher
Wang X, Wang C, Wang J, Zhao S, Zhang K, Wang J, et al. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt signaling pathways. Neuropharmacology. 2014;79:642-56 pubmed publisher
Li M, Riddle S, Frid M, El Kasmi K, McKinsey T, Sokol R, et al. Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol. 2011;187:2711-22 pubmed publisher
Cai Y, Cui W, Chen W, Wei P, Chi Y, Zhang P, et al. The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms. Cancer Cell Int. 2013;13:57 pubmed publisher
product information
SKU :
5356S
Product-Name :
HDAC1 (10E2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
62
Host :
Mouse
Target :
HDAC1
Primary-Protein :
HDAC1
Alt-Names :
DKFZp686H12203,GON-10,HD1,HDAC1,Histone deacetylase 1,RPD3,RPD3L1,reduced potassium dependency, yeast homolog-like 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.