| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; pigs ; loading ...; fig 4i
| Wang Z, Chen J, Wu X, Ma D, Zhang X, Li R, et al. PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection. PLoS Pathog. 2021;17:e1009940 pubmed publisher |
- immunohistochemistry - frozen section; zebrafish ; 1:1000; loading ...; fig 3a
| Łysyganicz P, Pooranachandran N, Liu X, Adamson K, Zielonka K, Elworthy S, et al. Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia. Front Cell Dev Biol. 2021;9:676214 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 5a
- western blot; human; loading ...; fig 2a
| Ko P, Choi J, Song S, Keum S, Jeong J, Hwang Y, et al. Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Int J Mol Sci. 2021;22: pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 1f
| Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed publisher |
- western blot; mouse; loading ...; fig 2d
| Shen Z, Ji K, Cai Z, Huang C, He X, Xu H, et al. Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy. Aging (Albany NY). 2021;13:9820-9837 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Siegel D, Bersie S, Harris P, Di Francesco A, Armstrong M, Reisdorph N, et al. A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation. Redox Biol. 2021;39:101840 pubmed publisher |
- immunocytochemistry; human; 1:10,000; loading ...; fig s1e
| Ha K, Nobuhara M, Wang Q, Walker R, Qian F, Schartner C, et al. The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus. elife. 2020;9: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3h
| Lian B, Pei Y, Jiang Y, Xue M, Li D, Li X, et al. Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer. Theranostics. 2020;10:11092-11109 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig 5a
| Van Bergen N, Ahmed S, Collins F, Cowley M, Vetro A, Dale R, et al. Mutations in the exocyst component EXOC2 cause severe defects in human brain development. J Exp Med. 2020;217: pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 4a
| Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5b
| Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:800; loading ...; fig 1f
| Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig e5d
| Eckert M, Coscia F, Chryplewicz A, Chang J, Hernandez K, Pan S, et al. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019;: pubmed publisher |
- immunocytochemistry; pigs ; 1:1000; loading ...; fig 6e
| Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1b
- western blot; human; loading ...; fig 4a
| Tan H, Liao H, Zhao L, Lu Y, Jiang S, Tao D, et al. HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB. Sci Rep. 2017;7:46376 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:800; loading ...; fig 4b
| Benbow S, Wozniak K, Kulesh B, Savage A, Slusher B, Littlefield B, et al. Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2017;32:151-162 pubmed publisher |
- immunocytochemistry; human; fig 5i
| McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig 3a
| . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher |
- immunocytochemistry; human; 1:300; loading ...; fig 3a
| Funabashi T, Katoh Y, Michisaka S, Terada M, Sugawa M, Nakayama K. Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol Biol Cell. 2017;28:624-633 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5a
| Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed publisher |
- immunocytochemistry; human; 1:800; loading ...; fig s2
- immunocytochemistry; mouse; 1:800; loading ...; fig 7a
| Yu F, Sharma S, Skowronek A, Erdmann K. The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep. 2016;6:35399 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 6c
| Medler T, Craig J, Fiorillo A, Feeney Y, Harrell J, Clevenger C. HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth. Mol Cancer Res. 2016;14:994-1008 pubmed |
- immunocytochemistry; human; fig 1
- western blot; human; fig 2
| Skoge R, Ziegler M. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. J Cell Sci. 2016;129:2972-82 pubmed publisher |
- immunohistochemistry; mouse; fig 2
| Airik R, Schueler M, Airik M, Cho J, Ulanowicz K, Porath J, et al. SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling. PLoS ONE. 2016;11:e0156081 pubmed publisher |
- immunohistochemistry; mouse; 1:800; fig 4d
| Benbow S, Cook B, Reifert J, Wozniak K, Slusher B, Littlefield B, et al. Effects of Paclitaxel and Eribulin in Mouse Sciatic Nerve: A Microtubule-Based Rationale for the Differential Induction of Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2016;29:299-313 pubmed publisher |
- immunocytochemistry; human; 1:800; fig 4
- western blot; human; fig 4
| Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed publisher |
- immunocytochemistry; human; fig 1
- western blot; human; fig 1
| Jovasevic V, Naghavi M, Walsh D. Microtubule plus end-associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells. J Cell Biol. 2015;211:323-37 pubmed publisher |
- immunocytochemistry; mouse
| Brown J, Santra T, Owens P, Morrison A, Barry F. Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia. Stem Cell Res. 2014;13:284-99 pubmed publisher |
- immunocytochemistry; human; 1:2000; fig 1-s3
| Wang W, Wu T, Kirschner M. The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium. elife. 2014;3:e03083 pubmed publisher |
- immunohistochemistry; pigs ; 1:800
| Hou L, Ma F, Yang J, Riaz H, Wang Y, Wu W, et al. Effects of histone deacetylase inhibitor oxamflatin on in vitro porcine somatic cell nuclear transfer embryos. Cell Reprogram. 2014;16:253-65 pubmed publisher |
- western blot; human; 1:10000
| Balmer N, Klima S, Rempel E, Ivanova V, Kolde R, Weng M, et al. From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014;88:1451-68 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500
| Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed publisher |
- immunocytochemistry; human; 1:1200; fig 1
| Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L. Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion. J Cell Sci. 2014;127:1631-9 pubmed publisher |
| Choi H, Madhu V, Shapiro I, Risbud M. Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation. Sci Rep. 2019;9:15469 pubmed publisher |
| Gilmore Hall S, Kuo J, Ward J, Zahra R, Morrison R, Perkins G, et al. CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. J Cell Biol. 2019;218:206-219 pubmed publisher |
| Arango D, Sturgill D, Alhusaini N, Dillman A, Sweet T, Hanson G, et al. Acetylation of Cytidine in mRNA Promotes Translation Efficiency. Cell. 2018;175:1872-1886.e24 pubmed publisher |
| Cooney A, Singh B, Loza L, Thornell I, Hippee C, Powers L, et al. Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus. Nucleic Acids Res. 2018;46:9591-9600 pubmed publisher |
| Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, et al. The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. PLoS Biol. 2018;16:e2005651 pubmed publisher |
| Li F, Sawada J, Komatsu M. R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature. Nat Commun. 2017;8:1720 pubmed publisher |
| Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher |
| Adler C, SANCHEZ ALVARADO A. PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration. Dev Biol. 2017;427:165-175 pubmed publisher |
| Loukil A, Tormanen K, Sütterlin C. The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome. J Cell Biol. 2017;216:1287-1300 pubmed publisher |
| Badgandi H, Hwang S, Shimada I, Loriot E, Mukhopadhyay S. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. J Cell Biol. 2017;216:743-760 pubmed publisher |
| Sundriyal S, Moniot S, Mahmud Z, YAO S, Di Fruscia P, Reynolds C, et al. Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket. J Med Chem. 2017;60:1928-1945 pubmed publisher |
| Xavier A, Ludwig R, Nagai M, de Almeida T, Watanabe H, Hirata M, et al. CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium. Sci Rep. 2016;6:25507 pubmed publisher |
| Yan Y, Tan K, Li C, Tran T, Chao S, Sugrue R, et al. Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza virus infection in vitro. J Allergy Clin Immunol. 2016;138:276-281.e15 pubmed publisher |
| Taylor S, Dantas T, Durán I, Wu S, Lachman R, Nelson S, et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. Nat Commun. 2015;6:7092 pubmed publisher |
| Boggs A, Vitolo M, Whipple R, Charpentier M, Goloubeva O, Ioffe O, et al. ?-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration. Cancer Res. 2015;75:203-15 pubmed publisher |
| Steg A, Burke M, Amm H, Katre A, Dobbin Z, Jeong D, et al. Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer. Oncotarget. 2014;5:7065-80 pubmed |
| Skoge R, Dölle C, Ziegler M. Regulation of SIRT2-dependent ?-tubulin deacetylation by cellular NAD levels. DNA Repair (Amst). 2014;23:33-8 pubmed publisher |
