product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MDA-5 (D74E4) Rabbit mAb
catalog :
5321S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • western blot; human; fig 6
Huang L, Stuart C, Takeda K, D'AGNILLO F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed publisher
  • western blot; human; fig 1
Hou Z, Zhang J, Han Q, Su C, Qu J, Xu D, et al. Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a. Sci Rep. 2016;6:26150 pubmed publisher
  • western blot; human; 1:1000; fig 5
Pham A, Santa Maria F, Lahiri T, Friedman E, Marié I, Levy D. PKR Transduces MDA5-Dependent Signals for Type I IFN Induction. PLoS Pathog. 2016;12:e1005489 pubmed publisher
  • western blot; mouse; fig 1
West A, Khoury-Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
  • western blot; mouse
Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed publisher
Chiba Y, Mizoguchi I, Mitobe K, Higuchi K, Nagai H, Nishigori C, et al. IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner. PLoS ONE. 2013;8:e76159 pubmed publisher
product information
SKU :
5321S
Product-Name :
MDA-5 (D74E4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
135
Host :
Rabbit
Target :
IFIH1
Primary-Protein :
IFIH1
Alt-Names :
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide,Helicard,Helicase with 2 CARD domains,Hlcd,IDDM19,IFIH1,Interferon-induced helicase C domain-containing protein 1,Interferon-induced with helicase C domain protein 1,MDA-5,MDA5,MGC133047,Melanoma differentiation-associated protein 5,Murabutide down-regulated protein,RH116,RNA helicase-DEAD box protein 116,interferon induced with helicase C domain 1,melanoma differentiation associated protein-5
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.