product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
AIF (D39D2) XP® Rabbit mAb
catalog :
5318
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D39D2
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 7e
Yoshitake S, Murakami T, Suzuma K, Yoshitake T, Uji A, Morooka S, et al. Anti-fumarase antibody promotes the dropout of photoreceptor inner and outer segments in diabetic macular oedema. Diabetologia. 2019;62:504-516 pubmed publisher
  • western blot; human; loading ...; fig 1d
Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2018;: pubmed publisher
  • immunohistochemistry; human; 1:1500; loading ...; fig s2b
NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Du K, Farhood A, Jaeschke H. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Arch Toxicol. 2017;91:761-773 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Nagase M, Kurihara H, Aiba A, Young M, Sakai T. Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. PLoS ONE. 2016;11:e0150886 pubmed publisher
  • immunocytochemistry; human; 1:400
  • western blot; human; 1:1000
Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed publisher
Kong F, Liu Z, Jain V, Shima K, Suzuki T, Muglia L, et al. Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages. J Immunol. 2017;199:3654-3667 pubmed publisher
Yang S, Zhao X, Xu H, Chen F, Xu Y, Li Z, et al. AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia. Int J Mol Sci. 2017;18: pubmed publisher
Dutta P, Haller E, Sharp A, Nanjundan M. MIR494 reduces renal cancer cell survival coinciding with increased lipid droplets and mitochondrial changes. BMC Cancer. 2016;16:33 pubmed publisher
Lee S, Moon H, Kim G, Cho J, Lee D, Dae Hee L, et al. Anion Transport or Nucleotide Binding by Ucp2 Is Indispensable for Ucp2-Mediated Efferocytosis. Mol Cells. 2015;38:657-62 pubmed publisher
Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden A, Lipinski M. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 2014;10:2208-22 pubmed publisher
Robaszkiewicz A, Erdélyi K, Kovacs K, Kovacs I, Bai P, Rajnavolgyi E, et al. Hydrogen peroxide-induced poly(ADP-ribosyl)ation regulates osteogenic differentiation-associated cell death. Free Radic Biol Med. 2012;53:1552-64 pubmed publisher
Ueda M, Daidoji T, Du A, Yang C, Ibrahim M, Ikuta K, et al. Highly pathogenic H5N1 avian influenza virus induces extracellular Ca2+ influx, leading to apoptosis in avian cells. J Virol. 2010;84:3068-78 pubmed publisher
product information
SKU :
5318S
Product-Name :
AIF (D39D2) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk, (B, Dg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
67
Host :
Rabbit
Target :
PDCD8
Primary-Protein :
PDCD8
Alt-Names :
AIF,AIFM1,Apoptosis-inducing factor 1, mitochondrial,MGC111425,PDCD8,Programmed cell death protein 8,apoptosis-inducing factor, mitochondrion-associated, 1,programmed cell death 8 (apoptosis-inducing factor),striatal apoptosis-inducing factor
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.