product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
S6 Ribosomal Protein (54D2) Mouse mAb (Alexa Fluor® 488 Conjugate)
catalog :
5317
clonality :
monoclonal
host :
house mouse
conjugate :
AF488
clone name :
54D2
reactivity :
human, house mouse, brown rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 9
Reference
Micel L, Tentler J, Tan A, Selby H, Brunkow K, Robertson K, et al. Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants. Mol Cancer Ther. 2015;14:317-25 pubmed publisher
Katayama R, Friboulet L, Koike S, Lockerman E, Khan T, Gainor J, et al. Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib. Clin Cancer Res. 2014;20:5686-96 pubmed publisher
Bitting R, Healy P, Creel P, Turnbull J, Morris K, Wood S, et al. A phase Ib study of combined VEGFR and mTOR inhibition with vatalanib and everolimus in patients with advanced renal cell carcinoma. Clin Genitourin Cancer. 2014;12:241-50 pubmed publisher
Siebel A, Cubillos Rojas M, Santos R, Schneider T, Bonan C, Bartrons R, et al. Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide. PLoS ONE. 2013;8:e75523 pubmed publisher
Rodriguez Martin T, Cuchillo Ibanez I, Noble W, Nyenya F, Anderton B, Hanger D. Tau phosphorylation affects its axonal transport and degradation. Neurobiol Aging. 2013;34:2146-57 pubmed publisher
Fabre B, Lambour T, Delobel J, Amalric F, Monsarrat B, Burlet Schiltz O, et al. Subcellular distribution and dynamics of active proteasome complexes unraveled by a workflow combining in vivo complex cross-linking and quantitative proteomics. Mol Cell Proteomics. 2013;12:687-99 pubmed publisher
Kim S, Jang Y, Chau G, Pyo S, Um S. Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma. Mod Pathol. 2013;26:327-35 pubmed publisher
Syed F, Sherris D, Paus R, Varmeh S, Singh S, Pandolfi P, et al. Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. Am J Pathol. 2012;181:1642-58 pubmed publisher
Papageorgiou A, Avruch J. A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation. Methods Mol Biol. 2012;821:187-214 pubmed publisher
product information
SKU :
5317S
Product-Name :
S6 Ribosomal Protein (54D2) Mouse mAb (Alexa Fluor® 488 Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Dm
Applications :
Flow cytometry
Product-Category :
Translational Control
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Mouse
Target :
S6 Ribosomal Protein
Primary-Protein :
S6
Alt-Names :
40S ribosomal protein S6,Phosphoprotein NP33,RPS6,RS6,ribosomal protein S6
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.