product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Synapsin-1 (D12G5) XP® Rabbit mAb
catalog :
5297
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D12G5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 24
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4c
Granger A, Wang W, Robertson K, El Rifai M, Zanello A, Bistrong K, et al. Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner. elife. 2020;9: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3e
  • immunohistochemistry; mouse; loading ...; fig 11a
  • western blot; mouse; loading ...; fig 3a, 8c
Zhang W, Zhou M, Lu W, Gong J, Gao F, Li Y, et al. CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes. Theranostics. 2020;10:3000-3021 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3a
Fu X, Peng J, Wang A, Luo Z. Tumor necrosis factor alpha mediates neuromuscular synapse elimination. Cell Discov. 2020;6:9 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1c
Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, et al. A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 1d
  • western blot; human; 1:2000; loading ...; fig 1b
Vogel S, Schäfer C, Hess S, Folz Donahue K, Nelles M, Minassian A, et al. The in vivo timeline of differentiation of engrafted human neural progenitor cells. Stem Cell Res. 2019;37:101429 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 3c
Soiza Reilly M, Meye F, Olusakin J, Telley L, Petit E, Chen X, et al. SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior. Mol Psychiatry. 2019;24:726-745 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 1d
Kaelberer M, Buchanan K, Klein M, Barth B, Montoya M, Shen X, et al. A gut-brain neural circuit for nutrient sensory transduction. Science. 2018;361: pubmed publisher
  • immunocytochemistry; mouse; 1:300; fig 4d
Wang S, Ko S, Kim Y, Jo S, Lee S, Jung S, et al. Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice. Exp Mol Med. 2018;50:e455 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2a
zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, et al. Protein kinase N1 critically regulates cerebellar development and long-term function. J Clin Invest. 2018;128:2076-2088 pubmed publisher
  • immunohistochemistry; human; 1:500; fig s10d
Birey F, Andersen J, Makinson C, Islam S, Wei W, Huber N, et al. Assembly of functionally integrated human forebrain spheroids. Nature. 2017;545:54-59 pubmed publisher
  • immunocytochemistry; rat; 1:2000; loading ...; fig s8d
Kim S, Im S, Oh S, Jeong S, Yoon E, Lee C, et al. Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network. Nat Commun. 2017;8:14346 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig st2
Zhu L, Almaca J, Dadi P, Hong H, Sakamoto W, Rossi M, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nat Commun. 2017;8:14295 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig st1
Ku T, Swaney J, Park J, Albanese A, Murray E, Cho J, et al. Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. Nat Biotechnol. 2016;34:973-81 pubmed publisher
  • immunocytochemistry; mouse; fig 3a
Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5
Pellett S, Schwartz M, Tepp W, Josephson R, Scherf J, Pier C, et al. Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. Sci Rep. 2015;5:14566 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100; fig s8
Saunders A, Oldenburg I, Berezovskii V, Johnson C, Kingery N, Elliott H, et al. A direct GABAergic output from the basal ganglia to frontal cortex. Nature. 2015;521:85-9 pubmed publisher
  • immunohistochemistry; mouse; 1:400
de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
Ji C, Tang M, Zeidler C, Hohfeld J, Johnson G. BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes. Autophagy. 2019;15:1199-1213 pubmed publisher
Zhao K, Shen C, Li L, Wu H, Xing G, Dong Z, et al. Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. J Neurosci. 2018;38:8860-8873 pubmed publisher
Karasmanis E, Phan C, Angelis D, Kesisova I, Hoogenraad C, McKenney R, et al. Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin. Dev Cell. 2018;46:204-218.e7 pubmed publisher
Zhang Y, Zhu Z, Liang H, Zhang L, Zhou Q, Ni H, et al. nNOS-CAPON interaction mediates amyloid-?-induced neurotoxicity, especially in the early stages. Aging Cell. 2018;17:e12754 pubmed publisher
Zhao K, Shen C, Lu Y, Huang Z, Li L, Rand C, et al. Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration. J Neurosci. 2017;37:3465-3477 pubmed publisher
Chen L, Miao Y, Chen L, Jin P, Zha Y, Chai Y, et al. The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots. Biomaterials. 2013;34:10172-81 pubmed publisher
Marker D, Puccini J, Mockus T, Barbieri J, Lu S, Gelbard H. LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein. J Neuroinflammation. 2012;9:261 pubmed publisher
product information
SKU :
5297S
Product-Name :
Synapsin-1 (D12G5) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Frozen)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
77
Host :
Rabbit
Target :
Synapsin-1
Primary-Protein :
SYN1
Alt-Names :
Brain protein 4.1,SYN1,SYN1a,SYN1b,SYNI,Synapsin I,Synapsin-1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.