Phospho-Bad (Ser112) (40A9) Rabbit mAb | Cell Signaling Technology 5284 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-Bad (Ser112) (40A9) Rabbit mAb

catalog :

5284

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

40A9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s5f	Sinha S, Thomas D, Chan S, Gao Y, Brunen D, Torabi D, et al. Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. Nat Commun. 2017;8:15580 pubmed publisher
flow cytometry; mouse	Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFÎºB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
western blot; human; 1:500; fig 5	Amato K, Wang S, Tan L, Hastings A, Song W, Lovly C, et al. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res. 2016;76:305-18 pubmed publisher
western blot; human; 1:1000; fig 1	Kreuz S, Holmes K, Tooze R, Lefevre P. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Mol Cancer. 2015;14:205 pubmed publisher
western blot; mouse; fig s4c	Green A, Maciel T, Hospital M, Yin C, Mazed F, Townsend E, et al. Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Sci Adv. 2015;1:e1500221 pubmed publisher
western blot; human	Rayavarapu R, Heiden B, Pagani N, Shaw M, Shuff S, Zhang S, et al. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. J Biol Chem. 2015;290:8722-33 pubmed publisher
western blot; human; fig 2	Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
western blot; human; fig 1	Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed publisher
	Brunen D, Garcia Barchino M, Malani D, Jagalur Basheer N, Lieftink C, Beijersbergen R, et al. Intrinsic resistance to PIM kinase inhibition in AML through p38?-mediated feedback activation of mTOR signaling. Oncotarget. 2016;7:37407-37419 pubmed publisher
	Guo X, Dong Y, Yin S, Zhao C, Huo Y, Fan L, et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis. 2013;4:e822 pubmed publisher
	Moon H, Yi J, Kim H, Lee H, Lee K, Yi M, et al. Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer. BMC Cancer. 2012;12:585 pubmed publisher

product information

SKU :

5284S

Product-Name :

Phospho-Bad (Ser112) (40A9) Rabbit mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Flow cytometry

Product-Category :

Apoptosis

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

Bad (Ser75) phosphate

Primary-Protein :

BAD

Alt-Names :

BAD,BBC2,BBC6,BCL-X/BCL-2 binding protein,BCL2-antagonist of cell death protein,BCL2-associated agonist of cell death,BCL2-binding component 6,BCL2-binding protein,BCL2L8,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,Bcl2-L-8

more info or order :

Cell Signaling Technology product webpage