product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PDGF Receptor α (D13C6) XP® Rabbit mAb
catalog :
5241
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D13C6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 5
Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
  • immunocytochemistry; human; 1:500; tbl 4
Agley C, Rowlerson A, Velloso C, Lazarus N, Harridge S. Isolation and quantitative immunocytochemical characterization of primary myogenic cells and fibroblasts from human skeletal muscle. J Vis Exp. 2015;:52049 pubmed publisher
  • immunohistochemistry; human
Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed publisher
  • immunohistochemistry; mouse
Kan L, Peng C, McGuire T, Kessler J. Glast-expressing progenitor cells contribute to heterotopic ossification. Bone. 2013;53:194-203 pubmed publisher
Cornillie J, Wozniak A, Van Renterghem B, Van Winkel N, Wellens J, Gebreyohannes Y, et al. Assessment of the platelet-derived growth factor receptor alpha antibody olaratumab in a panel of patient-derived soft tissue sarcoma xenografts. BMC Cancer. 2019;19:724 pubmed publisher
Larson J, Kasper L, Paugh B, Jin H, Wu G, Kwon C, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. 2019;35:140-155.e7 pubmed publisher
Ip C, Ng P, Jeong K, Shao S, Ju Z, Leonard P, et al. Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies. Nat Commun. 2018;9:4583 pubmed publisher
Obata Y, Horikawa K, Takahashi T, Akieda Y, Tsujimoto M, Fletcher J, et al. Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors. Oncogene. 2017;36:3661-3672 pubmed publisher
Ki D, He S, Rodig S, Look A. Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors. Oncogene. 2017;36:1058-1068 pubmed publisher
Hara Y, Yamashita T, Oishi N, Nio K, Hayashi T, Nomura Y, et al. TSU-68 ameliorates hepatocellular carcinoma growth by inhibiting microenvironmental platelet-derived growth factor signaling. Anticancer Res. 2015;35:1423-31 pubmed
Ohsaka A, Hirota Komatsu S, Araki M, Komatsu N. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. Biochem Biophys Res Commun. 2015;459:443-9 pubmed publisher
product information
SKU :
5241P
Product-Name :
PDGF Receptor α (D13C6) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
190
Host :
Rabbit
Target :
PDGFR-a
Primary-Protein :
PDGFRa
Alt-Names :
Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140A,CD140a antigen,MGC74795,PDGF-R-alpha,PDGFR2,PDGFRA,PGFRA,RHEPDGFRA,platelet-derived growth factor receptor, alpha polypeptide,rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.