product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Akt2 (L79B2) Mouse mAb
catalog :
5239
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L79B2
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 2b
Feng W, Cao Z, Lim P, Zhao H, Luo H, Mao N, et al. Rapid interrogation of cancer cell of origin through CRISPR editing. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • western blot; mouse; loading ...; fig 6b, 7a
  • western blot; human; loading ...; fig 4a
Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, et al. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021;296:100624 pubmed publisher
  • western blot; rat; 1:1000; fig 4
Caruso M, Zhang X, Ma D, Yang Z, Qi Y, Yi Z. Novel Endogenous, Insulin-Stimulated Akt2 Protein Interaction Partners in L6 Myoblasts. PLoS ONE. 2015;10:e0140255 pubmed publisher
  • western blot; mouse; 1:1000; fig s9
Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  • western blot; human; fig 2
Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed publisher
Holler M, Grottke A, Mueck K, Manes J, Jücker M, Rodemann H, et al. Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells. PLoS ONE. 2016;11:e0154745 pubmed publisher
Zhang W, Zhang X, González Cobos J, Stolwijk J, Matrougui K, Trebak M. Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia. J Biol Chem. 2015;290:5015-27 pubmed publisher
Yu Z, Xu Z, Disante G, Wright J, Wang M, Li Y, et al. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget. 2014;5:1083-90 pubmed
product information
SKU :
5239S
Product-Name :
Akt2 (L79B2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Mouse
Target :
Akt2
Primary-Protein :
Akt2
Alt-Names :
AKT2,Murine thymoma viral (v-akt) homolog-2,PKB beta,PKBB,PKBBETA,PRKBB,Protein kinase Akt-2,Protein kinase B beta,RAC-BETA,RAC-PK-beta,RAC-beta serine/threonine-protein kinase,rac protein kinase beta,v-akt murine thymoma viral oncogene homolog 2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.