product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GAPDH (D16H11) XP® Rabbit mAb
catalog :
5174P
quantity :
40 ul
price :
135 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 49
Published Application/Species/DilutionReference
  • western blot; human; fig 6e
Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-G1137 pubmed publisher
  • western blot; human; 1:1000; fig 2
  • western blot; mouse; 1:1000; fig 2
Liu Y, Xu Y, Guo S, Chen H. T cell factor-4 functions as a co-activator to promote NF-κB-dependent MMP-15 expression in lung carcinoma cells. Sci Rep. 2016;6:24025 pubmed publisher
  • western blot; mouse; fig 4
Wang X, Wan H, Wei X, Zhang Y, Qu P. CLI-095 decreases atherosclerosis by modulating foam cell formation in apolipoprotein E-deficient mice. Mol Med Rep. 2016;14:49-56 pubmed publisher
  • western blot; human; fig 4
Xia Z, Huang X, Chen K, Wang H, Xiao J, He K, et al. Proapoptotic Role of Potassium Ions in Liver Cells. Biomed Res Int. 2016;2016:1729135 pubmed publisher
  • western blot; human; 1:2000; fig s4
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  • western blot; human; fig 1
Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed publisher
  • western blot; human; fig 2
Khanom R, Nguyen C, Kayamori K, Zhao X, Morita K, Miki Y, et al. Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth. PLoS ONE. 2016;11:e0161163 pubmed publisher
  • western blot; human; fig 1d
Mason J, Davison-Versagli C, Leliaert A, Pape D, McCallister C, Zuo J, et al. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death Differ. 2016;: pubmed publisher
  • western blot; human; 1:1000; fig 5
Tian B, Maidana D, Dib B, Miller J, Bouzika P, Miller J, et al. miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0160887 pubmed publisher
  • western blot; human; 1:1000; fig 2
Qiao Y, Qian Y, Wang J, Tang X. Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cells. Oncol Lett. 2016;11:3702-3708 pubmed
  • western blot; rat; 1:1000; fig 1
Liu L, Wang C, Lin Y, Xi Y, Li H, Shi S, et al. Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Mol Med Rep. 2016;14:111-20 pubmed publisher
  • western blot; human; fig 2
Hoffmann C, Mao X, Dieterle M, Moreau F, Al Absi A, Steinmetz A, et al. CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis. Oncotarget. 2016;7:13688-705 pubmed publisher
  • western blot; human; fig 3
Reynolds J, Haque S, Williamson K, Ray D, Alexander M, Bruce I. Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus. Sci Rep. 2016;6:22341 pubmed publisher
  • western blot; human; fig 2
Li X, Wu J, Li Q, Shigemura K, Chung L, Huang W. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget. 2016;7:12869-84 pubmed publisher
  • western blot; human; 1:1000; fig 4
Montalbano M, Curcurù G, Shirafkan A, Vento R, Rastellini C, Cicalese L. Modeling of Hepatocytes Proliferation Isolated from Proximal and Distal Zones from Human Hepatocellular Carcinoma Lesion. PLoS ONE. 2016;11:e0153613 pubmed publisher
  • western blot; human; 1:1000; fig 2
Sharon C, Baranwal S, Patel N, Rodriguez-Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed
  • western blot; human; 1:1000; fig 2
Lu Q, Li J, Senkowski C, Tang Z, Wang J, Huang T, et al. Promoter Hypermethylation and Decreased Expression of Syncytin-1 in Pancreatic Adenocarcinomas. PLoS ONE. 2015;10:e0134412 pubmed publisher
  • western blot; human
Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
  • western blot; human; fig 3, 4
Puig M, Lugo R, Gabasa M, Giménez A, Velasquez A, Galgoczy R, et al. Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer. Mol Cancer Res. 2015;13:161-73 pubmed publisher
  • western blot; human
Li X, Liang Q, Liu W, Zhang N, Xu L, Zhang X, et al. Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. Oncogene. 2015;: pubmed publisher
  • western blot; human; fig 2b
  • western blot; mouse; fig 2b
Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher
  • western blot; mouse
Huang Z, Han Z, Ye B, Dai Z, Shan P, Lu Z, et al. Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes. Eur J Pharmacol. 2015;762:1-10 pubmed publisher
  • western blot; human
Bakke S, Feng Y, Nikolić N, Kase E, Moro C, Stensrud C, et al. Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects. PLoS ONE. 2015;10:e0119556 pubmed publisher
  • western blot; human
Tang X, Chen X, Xu Y, Qiao Y, Zhang X, Wang Y, et al. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. Cell Signal. 2015;27:1694-702 pubmed publisher
  • western blot; human; fig 1
Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
  • western blot; rat; 1:2500; fig 5
Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher
  • western blot; human; 1:2000; fig 6
Meng Z, Moroishi T, Mottier-Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
  • western blot; human; 1:5000
Howell M, Bailey L, Cozart M, Gannon B, Gottschall P. Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice. Acta Neuropathol Commun. 2015;3:54 pubmed publisher
  • western blot; mouse; fig 1,2,3,4,5,6
Izzo F, Mercogliano F, Venturutti L, Tkach M, Inurrigarro G, Schillaci R, et al. Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Res. 2014;16:491 pubmed publisher
  • western blot; mouse; fig 6
Herranz D, Ambesi-Impiombato A, Palomero T, Schnell S, Belver L, Wendorff A, et al. A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nat Med. 2014;20:1130-7 pubmed publisher
  • western blot; human
Del Nagro C, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, et al. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle. 2014;13:303-14 pubmed publisher
  • western blot; human
Waitkus M, Chandrasekharan U, Willard B, Tee T, Hsieh J, Przybycin C, et al. Signal integration and gene induction by a functionally distinct STAT3 phosphoform. Mol Cell Biol. 2014;34:1800-11 pubmed publisher
  • western blot; mouse; 1:5000
Dang T, Dobson-Stone C, Glaros E, Kim W, Hallupp M, Bartley L, et al. Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model. Dis Model Mech. 2013;6:1198-204 pubmed publisher
  • western blot; mouse
Rippo M, Babini L, Prattichizzo F, Graciotti L, Fulgenzi G, Tomassoni Ardori F, et al. Low FasL levels promote proliferation of human bone marrow-derived mesenchymal stem cells, higher levels inhibit their differentiation into adipocytes. Cell Death Dis. 2013;4:e594 pubmed publisher
Lu Y, Li S, Wu H, Bian Z, Xu J, Gu C, et al. Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells. Int J Mol Med. 2015;36:1223-32 pubmed publisher
Lannes J, L'Hôte D, Garrel G, Laverrière J, Cohen-Tannoudji J, Querat B. Rapid communication: A microRNA-132/212 pathway mediates GnRH activation of FSH expression. Mol Endocrinol. 2015;29:364-72 pubmed publisher
Xiang W, He J, Huang C, Chen L, Tao D, Wu X, et al. miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma. Oncotarget. 2015;6:4066-79 pubmed
Clemente-Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher
Wang D, Patel A, Shukla S, Zhang Y, Wang Y, Kathawala R, et al. Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2. Oncotarget. 2014;5:4529-42 pubmed
Gurung P, Anand P, Malireddi R, Vande Walle L, Van Opdenbosch N, Dillon C, et al. FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol. 2014;192:1835-46 pubmed publisher
Smith B, Burton L, HENDERSON V, Randle D, Morton D, Smith B, et al. Snail promotes epithelial mesenchymal transition in breast cancer cells in part via activation of nuclear ERK2. PLoS ONE. 2014;9:e104987 pubmed publisher
Giordano A, D'Angelillo A, Romano S, D'Arrigo P, Corcione N, Bisogni R, et al. Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells. Vascul Pharmacol. 2014;61:63-71 pubmed publisher
Folgiero V, Goffredo B, Filippini P, Masetti R, Bonanno G, Caruso R, et al. Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia. Oncotarget. 2014;5:2052-64 pubmed
Humphreys K, McKinnon R, Michael M. miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. PLoS ONE. 2014;9:e112288 pubmed publisher
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, et al. Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells. PLoS ONE. 2014;9:e96238 pubmed publisher
Lin W, Schmidt J, Creamer B, Triplett A, Wagner K. Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung. PLoS ONE. 2013;8:e60902 pubmed publisher
Liu Y, Du F, Chen W, Yao M, Lv K, Fu P. Knockdown of dual specificity phosphatase 4 enhances the chemosensitivity of MCF-7 and MCF-7/ADR breast cancer cells to doxorubicin. Exp Cell Res. 2013;319:3140-9 pubmed publisher
Kuhn E, Kurman R, Soslow R, Han G, Sehdev A, Morin P, et al. The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma. Am J Surg Pathol. 2012;36:1826-34 pubmed publisher
Song N, Ding Y, Zhuo W, He T, Fu Z, Chen Y, et al. The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells. Angiogenesis. 2012;15:697-711 pubmed publisher
product information
SKU :
5174P
Product-Name :
GAPDH (D16H11) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk, (Pg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
37
Host :
Rabbit
Target :
GAPDH
Primary-Protein :
GAPDH
Alt-Names :
G3P,G3PD,GAPD,GAPDH,Glyceraldehyde-3-phosphate dehydrogenase,MGC88685,aging-associated gene 9 protein,glyceraldehyde 3-phosphate dehydrogenase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.