product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Androgen Receptor (D6F11) XP® Rabbit mAb
catalog :
5153
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D6F11
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, mass cytometry
citations: 27
Published Application/Species/Sample/DilutionReference
  • mass cytometry; human; loading ...; fig 3a
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
  • western blot; human; loading ...; fig s2a
Zeng J, Liu W, Fan Y, He D, Li L. PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy. Theranostics. 2018;8:109-123 pubmed publisher
  • western blot; human; loading ...; fig 4j
Mahajan K, Malla P, Lawrence H, Chen Z, Kumar Sinha C, Malik R, et al. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017;31:790-803.e8 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 6a
  • western blot; human; 1:2000; loading ...; fig 5b
Hashimoto Y, Shiina M, Kato T, Yamamura S, Tanaka Y, Majid S, et al. The role of miR-24 as a race related genetic factor in prostate cancer. Oncotarget. 2017;8:16581-16593 pubmed publisher
  • western blot; human; loading ...; fig 2g
Tse B, Volpert M, Ratther E, Stylianou N, Nouri M, McGowan K, et al. Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene. 2017;36:3417-3427 pubmed publisher
  • western blot; human; fig 2a
Mu P, Zhang Z, Benelli M, Karthaus W, Hoover E, Chen C, et al. SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science. 2017;355:84-88 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 4b
Shiina M, Hashimoto Y, Kato T, Yamamura S, Tanaka Y, Majid S, et al. Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians. Oncotarget. 2017;8:8356-8368 pubmed publisher
  • western blot; human; fig 1
Ho T, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, et al. Regulation of PCGEM1 by p54/nrb in prostate cancer. Sci Rep. 2016;6:34529 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1d
Shen H, Zhao L, Feng X, Xu C, Li C, Niu Y. Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER-/Her2+ breast cancer. Oncotarget. 2016;7:60407-60418 pubmed publisher
  • immunohistochemistry; human; fig s3
Hatem R, El Botty R, Chateau Joubert S, Servely J, Labiod D, de Plater L, et al. Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers. Oncotarget. 2016;7:48206-48219 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5f
Yard B, Adams D, Chie E, Tamayo P, Battaglia J, Gopal P, et al. A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nat Commun. 2016;7:11428 pubmed publisher
  • immunohistochemistry; human; 1:200; fig e9
Shu S, Lin C, He H, Witwicki R, Tabassum D, Roberts J, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529:413-417 pubmed publisher
  • western blot; human; fig s11
Pomerantz M, Li F, Takeda D, Lenci R, Chonkar A, Chabot M, et al. The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nat Genet. 2015;47:1346-51 pubmed publisher
  • western blot; human; fig 3
Li X, Cui P, Jiang H, Guo Y, Pishdari B, Hu M, et al. Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action. Am J Transl Res. 2015;7:574-86 pubmed
Krawczyk N, Neubacher M, Meier Stiegen F, Neubauer H, Niederacher D, Ruckhäberle E, et al. Determination of the androgen receptor status of circulating tumour cells in metastatic breast cancer patients. BMC Cancer. 2019;19:1101 pubmed publisher
Kounatidou E, Nakjang S, McCracken S, Dehm S, Robson C, Jones D, et al. A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. Nucleic Acids Res. 2019;47:5634-5647 pubmed publisher
Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed publisher
Takeda D, Spisak S, Seo J, Bell C, O CONNOR E, Korthauer K, et al. A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer. Cell. 2018;174:422-432.e13 pubmed publisher
Guarnieri A, Towers C, Drasin D, Oliphant M, Andrysik Z, Hotz T, et al. The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L. Oncogene. 2018;37:3879-3893 pubmed publisher
Zheng Y, Wang Z, Ding X, Zhang W, Li G, Liu L, et al. A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma. Cancer Cell Int. 2018;18:6 pubmed publisher
Duex J, Swain K, Dancik G, Paucek R, Owens C, Churchill M, et al. Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer. Mol Cancer Res. 2018;16:69-77 pubmed publisher
Scher H, Graf R, Schreiber N, McLaughlin B, Jendrisak A, Wang Y, et al. Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer. Cancer Res. 2017;77:5687-5698 pubmed publisher
Thomas J, Longen C, Oyer H, Chen N, Maher C, Salvino J, et al. Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. Cancer Res. 2017;77:2439-2452 pubmed publisher
Crespo M, van Dalum G, Ferraldeschi R, Zafeiriou Z, Sideris S, Lorente D, et al. Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents. Br J Cancer. 2015;112:1166-74 pubmed publisher
Yu M, Jiang M, Yang C, Wu Y, Liu Y, Cui Y, et al. Maternal high-fat diet affects Msi/Notch/Hes signaling in neural stem cells of offspring mice. J Nutr Biochem. 2014;25:227-31 pubmed publisher
Nie H, Cao Q, Zhu L, Gong Y, Gu J, He Z. Acetylcholine acts on androgen receptor to promote the migration and invasion but inhibit the apoptosis of human hepatocarcinoma. PLoS ONE. 2013;8:e61678 pubmed publisher
Ao J, Meng J, Zhu L, Nie H, Yang C, Li J, et al. Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion. Mol Oncol. 2012;6:507-15 pubmed publisher
product information
SKU :
5153P
Product-Name :
Androgen Receptor (D6F11) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
Nuclear Receptor Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Rabbit
Target :
Androgen Receptor
Primary-Protein :
AR
Alt-Names :
AIS,ANDR,AR,Androgen receptor,DHTR,Dihydrotestosterone receptor,HUMARA,HYSP1,KD,NR3C4,Nuclear receptor subfamily 3 group C member 4,SBMA,SMAX1,TFM
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.