product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
DUSP4/MKP2 (D9A5) Rabbit mAb
catalog :
5149
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D9A5
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section, other
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Xue Z, Vis D, Bruna A, Sustic T, van Wageningen S, Batra A, et al. MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models. Cell Res. 2018;28:719-729 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; fig 3b
Gaggianesi M, Turdo A, Chinnici A, Lipari E, Apuzzo T, Benfante A, et al. IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition. Cancer Res. 2017;77:3268-3279 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 4
  • western blot; human; fig 4
Hutchinson K, Johnson D, Johnson A, Sanchez V, Kuba M, Lu P, et al. ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget. 2015;6:22348-60 pubmed
Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed publisher
Devereaux K, Dall Armi C, Alcazar Roman A, Ogasawara Y, Zhou X, Wang F, et al. Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis. PLoS ONE. 2013;8:e76405 pubmed publisher
product information
SKU :
5149S
Product-Name :
DUSP4/MKP2 (D9A5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
42
Host :
Rabbit
Target :
DUSP4/MKP2
Primary-Protein :
MKP-2
Alt-Names :
DUS4,DUSP4,Dual specificity protein phosphatase 4,Dual specificity protein phosphatase hVH2,HVH2,MAP kinase phosphatase 2,MKP-2,MKP2,Mitogen-activated protein kinase phosphatase 2,TYP,VH1 homologous phosphatase 2,VH2,dual specificity phosphatase 4,serine/threonine specific protein phosphatase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.