| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:2000; loading ...; fig 3a
| Hoshino A, Wang W, Wada S, McDermott Roe C, Evans C, Gosis B, et al. The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019;575:375-379 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed publisher |
- western blot; rat; 1:500; loading ...; fig 8b
| Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5d
| Chang H, Di T, Wang Y, Zeng X, Li G, Wan Q, et al. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127:350-361 pubmed publisher |
- western blot; human; loading ...; fig 2d
| Zhang J, He J, Johnson J, Rahman F, Gavathiotis E, Cuervo A, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Bechelli J, Vergara L, Smalley C, Buzhdygan T, Bender S, Zhang W, et al. Atg5 Supports Rickettsia australis Infection in Macrophages In Vitro and In Vivo. Infect Immun. 2019;87: pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 1m
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- western blot; mouse; 1:1000; loading ...; fig 6d
| Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed publisher |
- western blot; mouse; loading ...; fig 2c
| Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher |
- western blot; mouse; loading ...; fig 1e
| Perot B, Boussier J, Yatim N, Rossman J, Ingersoll M, Albert M. Autophagy diminishes the early interferon-? response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis. 2018;9:539 pubmed publisher |
- western blot; human; loading ...; fig 8a
| Rademaker G, Hennequière V, Brohée L, Nokin M, Lovinfosse P, Durieux F, et al. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene. 2018;37:4398-4412 pubmed publisher |
- western blot; rat; loading ...; fig 5a
| Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed publisher |
- western blot; human; loading ...; fig s1d
| Zeng J, Liu W, Fan Y, He D, Li L. PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy. Theranostics. 2018;8:109-123 pubmed publisher |
- western blot; mouse; 1:3000; loading ...; fig 4b
| Sun H, Krauss R, Chang J, Teng B. PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction. J Lipid Res. 2018;59:207-223 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Sorokina I, Denisenko T, Imreh G, Tyurin Kuzmin P, Kaminskyy V, Gogvadze V, et al. Involvement of autophagy in the outcome of mitotic catastrophe. Sci Rep. 2017;7:14571 pubmed publisher |
- western blot; mouse; loading ...; fig 6c
| Hos N, Ganesan R, Gutierrez S, Hos D, Klimek J, Abdullah Z, et al. Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol. 2017;216:4107-4121 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Ruan H, Ma Y, Torres S, Zhang B, Feriod C, Heck R, et al. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017;31:1655-1665 pubmed publisher |
- western blot; mouse; ; loading ...; fig 5c
| Yi W, Gupta S, Ricker E, Manni M, Jessberger R, Chinenov Y, et al. The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. Nat Commun. 2017;8:254 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 8c
| Liu C, Choi H, Johnson Z, Tian J, Shapiro I, Risbud M. Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus. Sci Rep. 2017;7:4543 pubmed publisher |
- western blot; human; loading ...; fig s5
| Courtial L, Picco V, Grover R, Cormerais Y, Rottier C, Labbe A, et al. The c-Jun N-terminal kinase prevents oxidative stress induced by UV and thermal stresses in corals and human cells. Sci Rep. 2017;7:45713 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 1g
- western blot; mouse; 1:2000; loading ...; fig 6a
| Chen S, Jing Y, Kang X, Yang L, Wang D, Zhang W, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017;45:1144-1158 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4c
| Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 3b
- western blot; human; loading ...; fig 3a
| Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher |
- western blot; human; loading ...; fig 1e
| Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed publisher |
- western blot; mouse; loading ...; fig 3d
| Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher |
- western blot; mouse; loading ...; fig 3a
| Liu L, Tao Z, Zheng L, Brooke J, Smith C, Liu D, et al. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death Discov. 2016;2:16066 pubmed |
- western blot; rat; 1:1000; loading ...; fig 2a
| Yang M, Wang B, Miao L, Xu X, He X. Autophagy is involved in aldosterone‑induced mesangial cell proliferation. Mol Med Rep. 2016;14:4638-4642 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 2c
| Gupta S, Zeglinski M, Rattan S, Landry N, Ghavami S, Wigle J, et al. Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts. Oncotarget. 2016;7:78516-78531 pubmed publisher |
- immunoprecipitation; human; loading ...; fig 4b
- western blot; human; loading ...; fig 4a
| Chan S, Lee J, Narula M, Ou J. Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6. J Virol. 2016;90:10928-10935 pubmed publisher |
- western blot; mouse; loading ...; fig 1g
| Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher |
- western blot; mouse; loading ...; fig 7f
- western blot; human; 1:150; loading ...; fig s3c
| Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, et al. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Sci Adv. 2016;2:e1601167 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 7d
- western blot; mouse; loading ...; fig 2f
| Qin Y, Liu Y, Hao W, Decker Y, Tomic I, Menger M, et al. Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice. J Immunol. 2016;197:3281-3292 pubmed |
- western blot; human; fig s1f
| Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed |
- western blot; human; loading ...; fig 1a
- western blot; mouse; loading ...; fig 1b
| Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed |
- western blot; mouse; loading ...; fig 1c
| Pan H, Zhong X, Lee S. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis. BMC Biochem. 2016;17:14 pubmed publisher |
- western blot; mouse; fig 3
| Hamlin A, Basford J, Jaeschke A, Hui D. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. J Biol Chem. 2016;291:16610-9 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1d
| Choi H, Merceron C, Mangiavini L, Seifert E, Schipani E, Shapiro I, et al. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling. Autophagy. 2016;12:1631-46 pubmed publisher |
- western blot; mouse; loading ...; fig 1c
| Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher |
- western blot; mouse; fig 1
| Liu L, Zheng L, Zou P, Brooke J, Smith C, Long Y, et al. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes. Cell Cycle. 2016;15:2033-41 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 1d
| Zeng J, Jing Y, Shi R, Pan X, Lai F, Liu W, et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. Cell Cycle. 2016;15:1602-10 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 6d
- western blot; human; loading ...; fig 2e
| Ranjan A, Srivastava S. Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis. Sci Rep. 2016;6:26165 pubmed publisher |
- western blot; rat; 1:1000; fig 2
| Liu L, Wang C, Lin Y, Xi Y, Li H, Shi S, et al. Suppression of calcium?sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Mol Med Rep. 2016;14:111-20 pubmed publisher |
- western blot; zebrafish ; 1:1000; loading ...; fig s1c
| Huang G, Zhang F, Ye Q, Wang H. The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erb? and indirectly via Cebpb/(C/ebp?) in zebrafish. Autophagy. 2016;12:1292-309 pubmed publisher |
- western blot; human; fig 2
| Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Walter C, Clemens L, Müller A, Fallier Becker P, Proikas Cezanne T, Riess O, et al. Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro. Neuropharmacology. 2016;108:24-38 pubmed publisher |
- western blot; human; loading ...
| Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed publisher |
- western blot; human; loading ...; fig 3
| Chen K, Lin C, Huang C, Chen S, Wu S, Chiang H, et al. Dual Roles of 17-? Estradiol in Estrogen Receptor-dependent Growth Inhibition in Renal Cell Carcinoma. Cancer Genomics Proteomics. 2016;13:219-30 pubmed |
- western blot; human; loading ...; fig 7f
| Li Z, Ji X, Wang W, Liu J, Liang X, Wu H, et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS ONE. 2016;11:e0153526 pubmed publisher |
- western blot; human; fig 2
| Li C, Jung S, Yang Y, Kim K, Lim J, Cheon C, et al. Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines. Int J Oncol. 2016;48:2639-46 pubmed publisher |
- western blot; mouse; 1:1000; tbl 1
| Krishnan V, White Z, McMahon C, Hodgetts S, Fitzgerald M, Shavlakadze T, et al. A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice. J Neuropathol Exp Neurol. 2016;75:464-78 pubmed publisher |
- western blot; mouse; loading ...; fig 3e
| Chen S, Wang C, Yeo S, Liang C, Okamoto T, Sun S, et al. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 2016;30:856-69 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3b
| Zhang W, Shi H, Zhang M, Liu B, Mao S, Li L, et al. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation. Int J Biochem Cell Biol. 2016;73:127-136 pubmed publisher |
- western blot; human; fig 3
| Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, et al. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. elife. 2016;5: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4b
| Pawar K, Hanisch C, Palma Vera S, Einspanier R, Sharbati S. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Sci Rep. 2016;6:19416 pubmed publisher |
- western blot; rat; 1:1000; fig 3
| Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher |
| Sulkshane P, Teni T. BH3 mimetic Obatoclax (GX15-070) mediates mitochondrial stress predominantly via MCL-1 inhibition and induces autophagy-dependent necroptosis in human oral cancer cells. Oncotarget. 2017;8:60060-60079 pubmed publisher |
| Liu H, Huan L, Yin J, Qin M, Zhang Z, Zhang Z, et al. Role of microRNA-130a in myocardial hypoxia/reoxygenation injury. Exp Ther Med. 2017;13:759-765 pubmed publisher |
| Yu Y, Li S, Wang Z, He J, Ding Y, Zhang H, et al. Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice. Sci Rep. 2017;7:43684 pubmed publisher |
| Afiyatullov S, Leshchenko E, Berdyshev D, Sobolevskaya M, Antonov A, Denisenko V, et al. Zosteropenillines: Polyketides from the MarineDerived Fungus Penicillium thomii. Mar Drugs. 2017;15: pubmed publisher |
| Moruno Manchon J, Uzor N, Kesler S, Wefel J, Townley D, Nagaraja A, et al. TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. Aging (Albany NY). 2016;8:3507-3519 pubmed publisher |
| Moon J, Lee J, Lee Y, Park S. Autophagy flux induced by ginsenoside-Rg3 attenuates human prion protein-mediated neurotoxicity and mitochondrial dysfunction. Oncotarget. 2016;7:85697-85708 pubmed publisher |
| Kim J, Jung J, Koo J, Cho W, Lee W, Kim C, et al. Diversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interaction. Nat Commun. 2016;7:13196 pubmed publisher |
| Huang M, Garcia J, Thomas D, Zhu L, Nguyen L, Chan S, et al. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget. 2016;7:74917-74930 pubmed publisher |
| Li S, Liu C, Gu L, Wang L, Shang Y, Liu Q, et al. Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36. Open Biol. 2016;6: pubmed publisher |
| Arroba A, Rodriguez de la Rosa L, Murillo Cuesta S, Vaquero Villanueva L, Hurle J, Varela Nieto I, et al. Autophagy resolves early retinal inflammation in Igf1-deficient mice. Dis Model Mech. 2016;9:965-74 pubmed publisher |
| Choi M, Kim H, Ham M, Choi D, Lee T, Shin D. Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes. Sci Rep. 2016;6:28476 pubmed publisher |
| Chung K, Jeong E, Park H, An H, Yu S. Mediation of Autophagic Cell Death by Type 3 Ryanodine Receptor (RyR3) in Adult Hippocampal Neural Stem Cells. Front Cell Neurosci. 2016;10:116 pubmed publisher |
| Moon J, Lee J, Nazim U, Lee Y, Seol J, Eo S, et al. Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells. Oncotarget. 2016;7:29989-30002 pubmed publisher |
| Xu Y, Zhou Q, Xin W, Li Z, Chen L, Wan Q. Autophagy downregulation contributes to insulin resistance mediated injury in insulin receptor knockout podocytes in vitro. Peerj. 2016;4:e1888 pubmed publisher |
| Moon J, Lee J, Lee Y, Park S. Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1. Oncotarget. 2016;7:29944-57 pubmed publisher |
| Su H, Waldron R, Gong R, Ramanujan V, Pandol S, Lugea A. The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. PLoS ONE. 2016;11:e0148999 pubmed publisher |
