product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
catalog :
5102S
quantity :
200 ul
price :
291 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
immunoprecipitation
citations: 10
Published Application/Species/DilutionReference
Ohashi K, Nagata Y, Wada E, Zammit P, Shiozuka M, Matsuda R. Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade. Exp Cell Res. 2015;333:228-37 pubmed publisher
Chong M, Loh M, Thakkar B, Pang B, Iacopetta B, Soong R. Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation. Int J Cancer. 2014;134:1232-8 pubmed publisher
Badescu A, Couvelard A, Handra-Luca A. Akt pathway protein expression in gastrointestinal Kaposi sarcomas: relevance for tumor biology. APMIS. 2014;122:518-25 pubmed publisher
Miura H, Matsuda M, Aoki K. Development of a FRET biosensor with high specificity for Akt. Cell Struct Funct. 2014;39:9-20 pubmed
Yoshida R, Nagata M, Nakayama H, Niimori-Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher
García-Claver A, Lorente M, Mur P, Campos-Martin Y, Mollejo M, Velasco G, et al. Gene expression changes associated with erlotinib response in glioma cell lines. Eur J Cancer. 2013;49:1641-53 pubmed publisher
Mathew J, Loranger A, Gilbert S, Faure R, Marceau N. Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling. Exp Cell Res. 2013;319:474-86 pubmed publisher
Dzieran J, Fabian J, Feng T, Coulouarn C, Ilkavets I, Kyselova A, et al. Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS ONE. 2013;8:e72252 pubmed publisher
Wang L, Liu X, Wu Y, Wu W, Wu Y. Involvement of ROS in the inhibitory effect of thermotherapy combined with chemotherapy on A549 human lung adenocarcinoma cell growth through the Akt pathway. Oncol Rep. 2012;28:1369-75 pubmed publisher
Reddiconto G, Toto C, Palamà I, De Leo S, de Luca E, De Matteis S, et al. Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors, preserving normal stem cells. Blood. 2012;119:2335-45 pubmed publisher
product information
SKU :
5102S
Product-Name :
Phospho-Akt (Ser473) (587F11) Mouse mAb (Biotinylated)
Size :
200 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Hm, (Mk)
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Mouse
Target :
Akt1 (Ser473) phosphate/Akt2 (Ser474) phosphate/Akt3 (Ser472) phosphate
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.