product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Btk (Tyr223) Antibody
catalog :
5082
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6a
Chong I, Aronson L, Bryant H, Gulati A, Campbell J, Elliott R, et al. Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer. Gut. 2018;67:1780-1792 pubmed publisher
  • western blot; human; loading ...; fig 5d
Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo S, et al. Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene. 2017;36:2366-2376 pubmed publisher
  • western blot; human; fig 5b
Dai B, Chen A, Corkum C, Peroutka R, Landon A, Houng S, et al. Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. 2016;35:2979-90 pubmed publisher
  • western blot; human; 1:1000; fig 5
Lorkova L, Scigelova M, Arrey T, Vit O, Pospisilova J, Doktorova E, et al. Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells. PLoS ONE. 2015;10:e0135314 pubmed publisher
  • western blot; mouse; fig 2b
Chen Z, Shojaee S, Buchner M, Geng H, Lee J, Klemm L, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015;521:357-61 pubmed publisher
Umezawa Y, Akiyama H, Okada K, Ishida S, Nogami A, Oshikawa G, et al. Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). J Biol Chem. 2017;292:19639-19655 pubmed publisher
product information
SKU :
5082P
Product-Name :
Phospho-Btk (Tyr223) Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
77
Host :
Rabbit
Target :
BTK (Tyr223) phosphate
Primary-Protein :
Btk
Alt-Names :
AGMX1,AT,ATK,Agammaglobulinaemia tyrosine kinase,B-cell progenitor kinase,BPK,BTK,Bruton agammaglobulinemia tyrosine kinase,Bruton tyrosine kinase,IMD1,MGC126261,MGC126262,PSCTK1,Tyrosine-protein kinase BTK,XLA,dominant-negative kinase-deficient Brutons tyrosine kinase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.