product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
mTOR (7C10) Rabbit mAb (Alexa Fluor® 488 Conjugate)
catalog :
5043
clonality :
monoclonal
host :
rabbit
conjugate :
AF488
clone name :
7C10
reactivity :
human, mouse, rat
application :
flow cytometry
citations: 11
Reference
Zhang X, Yang B, Wang J, Mo X, Zhang J, Hua Z. FADD is essential for glucose uptake and survival of thymocytes. Biochem Biophys Res Commun. 2014;451:202-7 pubmed publisher
Stellrecht C, Vangapandu H, Le X, Mao W, Shentu S. ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells. J Hematol Oncol. 2014;7:23 pubmed publisher
Wang L, Hu H, Pan Y, Wang R, Li Y, Shen L, et al. PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup. PLoS ONE. 2014;9:e88291 pubmed publisher
Li J, Zhu H, Chen T, Zou L, Wang X, Zhao H, et al. Roles of mTOR and p-mTOR in gastrointestinal stromal tumors. Asian Pac J Cancer Prev. 2013;14:5925-8 pubmed
Komori Y, Yada K, Ohta M, Uchida H, Iwashita Y, Fukuzawa K, et al. Mammalian target of rapamycin signaling activation patterns in pancreatic neuroendocrine tumors. J Hepatobiliary Pancreat Sci. 2014;21:288-95 pubmed publisher
Vajpayee N, Thakral C, Gopaluni S, Newman N, Gajra A. Activation of mammalian target of rapamycin in diffuse large B-cell lymphoma: a clinicopathological study. Leuk Res. 2012;36:1403-9 pubmed publisher
Murai A, Asa S, Kodama A, Hirata A, Yanai T, Sakai H. Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines. BMC Vet Res. 2012;8:128 pubmed publisher
Murakami A, Gomi K, Tanaka M, Ohyama M, Itani Y, Ishikawa H, et al. Unilateral glomerulocystic kidney disease associated with tuberous sclerosis complex in a neonate. Pathol Int. 2012;62:209-15 pubmed publisher
Wills J, Credle J, Oaks A, Duka V, Lee J, Jones J, et al. Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways. PLoS ONE. 2012;7:e30745 pubmed publisher
Reddiconto G, Toto C, Palamà I, De Leo S, de Luca E, De Matteis S, et al. Targeting of GSK3? promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors, preserving normal stem cells. Blood. 2012;119:2335-45 pubmed publisher
Walsh S, Flanagan L, Quinn C, Evoy D, McDermott E, Pierce A, et al. mTOR in breast cancer: differential expression in triple-negative and non-triple-negative tumors. Breast. 2012;21:178-82 pubmed publisher
product information
SKU :
5043S
Product-Name :
mTOR (7C10) Rabbit mAb (Alexa Fluor® 488 Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
mTOR
Primary-Protein :
mTOR
Alt-Names :
FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein,FKBP12-rapamycin complex-associated protein 1,FLJ44809,FRAP,FRAP1,FRAP2,Mammalian target of rapamycin,RAFT1,RAPT1,Rapamycin target protein 1,Serine/threonine-protein kinase mTOR,mTOR,mechanistic target of rapamycin (serine/threonine kinase),rapamycin and FKBP12 target 1,rapamycin associated protein FRAP2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.