product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
DNMT1 (D63A6) XP® Rabbit mAb
catalog :
5032P
quantity :
40 ul
price :
135 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 11
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:1000; fig 4
Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed publisher
  • western blot (knockdown validation); human; 1:1000; fig 3
Nakamura K, Nakabayashi K, Htet Aung K, Aizawa K, Hori N, Yamauchi J, et al. DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status. PLoS ONE. 2015;10:e0120545 pubmed publisher
  • western blot; mouse; fig 5b
  • immunohistochemistry; mouse; fig 6b
Chang Y, Yang C, Pan S, Chou Y, Chang F, Lai C, et al. DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys. J Clin Invest. 2016;126:721-31 pubmed publisher
  • western blot; human
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • western blot; rat; 1:2500; fig 6
Götze S, Schumacher E, Kordes C, Haussinger D. Epigenetic Changes during Hepatic Stellate Cell Activation. PLoS ONE. 2015;10:e0128745 pubmed publisher
  • western blot; mouse
Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour A, Kol N, Salmon-Divon M, et al. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation. Science. 2015;347:1002-6 pubmed publisher
  • western blot; human
Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher
Mei Q, Chen M, Lu X, Li X, Duan F, Wang M, et al. An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma. Oncotarget. 2015;6:16698-711 pubmed
Nakamura K, Aizawa K, Nakabayashi K, Kato N, Yamauchi J, Hata K, et al. DNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis. PLoS ONE. 2013;8:e54036 pubmed publisher
Zhang Y, Andrews G, Wang L. Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP. Nucleic Acids Res. 2012;40:4850-60 pubmed publisher
Zhang Y, Wang L. Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ. FEBS Lett. 2011;585:1269-75 pubmed publisher
product information
SKU :
5032P
Product-Name :
DNMT1 (D63A6) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk, (Hm, B, Dg, GP, Hr)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
200
Host :
Rabbit
Target :
DNMT1
Primary-Protein :
DNMT1
Alt-Names :
AIM,CXXC finger protein 9,CXXC-type zinc finger protein 9,CXXC9,DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5-)-methyltransferase 1,DNA MTase HsaI,DNA methyltransferase 1,DNA methyltransferase HsaI,DNMT,DNMT1,FLJ16293,M.HsaI,MCMT,MGC104992
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.