product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MEF2C (D80C1) XP® Rabbit mAb
catalog :
5030
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D80C1
reactivity :
human, mouse, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, ChIP-Seq
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5n
Qin L, Fu X, Ma J, Lin M, Zhang P, Wang Y, et al. Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes. Commun Biol. 2021;4:402 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 4e
Tacconi C, He Y, Ducoli L, Detmar M. Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells. Angiogenesis. 2020;: pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, et al. E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator. Science. 2018;362: pubmed publisher
  • immunocytochemistry; mouse; fig 5a
  • immunohistochemistry; zebrafish ; fig 5i
Raices M, Bukata L, Sakuma S, Borlido J, Hernandez L, Hart D, et al. Nuclear Pores Regulate Muscle Development and Maintenance by Assembling a Localized Mef2C Complex. Dev Cell. 2017;41:540-554.e7 pubmed publisher
  • immunocytochemistry; mouse; fig 3e
Maltabe V, Barka E, Kontonika M, Florou D, Kouvara Pritsouli M, Roumpi M, et al. Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int. 2016;2016:8305624 pubmed publisher
  • ChIP-Seq; human; fig s2
  • immunoprecipitation; human; fig s2
Kong N, Davis M, Chai L, Winoto A, Tjian R. MEF2C and EBF1 Co-regulate B Cell-Specific Transcription. PLoS Genet. 2016;12:e1005845 pubmed publisher
  • western blot; mouse; 1:500; fig 5k
Quijada P, Hariharan N, Cubillo J, Bala K, Emathinger J, Wang B, et al. Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment. J Biol Chem. 2015;290:25411-26 pubmed publisher
  • immunocytochemistry; mouse
Fu Y, Huang C, Xu X, Gu H, Ye Y, Jiang C, et al. Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails. Cell Res. 2015;25:1013-24 pubmed publisher
  • immunocytochemistry; mouse; fig 1b
  • immunocytochemistry; human; fig s1a
  • western blot; human; fig s1b
Belian E, Noseda M, Abreu Paiva M, Leja T, Sampson R, Schneider M. Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5. PLoS ONE. 2015;10:e0125384 pubmed publisher
  • western blot; human
Wang X, Pesakhov S, Harrison J, Danilenko M, Studzinski G. ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells. J Cell Physiol. 2014;229:856-67 pubmed publisher
  • western blot; human
Murata T, Narita Y, Sugimoto A, Kawashima D, Kanda T, Tsurumi T. Contribution of myocyte enhancer factor 2 family transcription factors to BZLF1 expression in Epstein-Barr virus reactivation from latency. J Virol. 2013;87:10148-62 pubmed publisher
  • western blot; human
Dessalle K, Euthine V, Chanon S, Delarichaudy J, Fujii I, Rome S, et al. SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors. PLoS ONE. 2012;7:e50878 pubmed publisher
Stone N, Gifford C, Thomas R, Pratt K, Samse Knapp K, Mohamed T, et al. Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019;25:87-102.e9 pubmed publisher
Tarumoto Y, Lu B, Somerville T, Huang Y, Milazzo J, Wu X, et al. LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia. Mol Cell. 2018;69:1017-1027.e6 pubmed publisher
Perroud J, Bernheim L, Frieden M, Koenig S. Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. J Cell Sci. 2017;130:3083-3093 pubmed publisher
Seo H, Kim H, Kang M, Ryum J, Yi E, Cho J. Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation. Sci Rep. 2016;6:34614 pubmed publisher
Pon J, Wong J, Saberi S, Alder O, Moksa M, Grace Cheng S, et al. MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation. Nat Commun. 2015;6:7953 pubmed publisher
Badodi S, Baruffaldi F, Ganassi M, Battini R, Molinari S. Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition. Cell Cycle. 2015;14:1517-28 pubmed publisher
Zhang M, Zhu B, Davie J. Alternative splicing of MEF2C pre-mRNA controls its activity in normal myogenesis and promotes tumorigenicity in rhabdomyosarcoma cells. J Biol Chem. 2015;290:310-24 pubmed publisher
Lee Y, Karuppagounder S, Shin J, Lee Y, Ko H, Swing D, et al. Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci. 2013;16:1392-400 pubmed publisher
Barneda Zahonero B, Román González L, Collazo O, Rafati H, Islam A, Bussmann L, et al. HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages. PLoS Genet. 2013;9:e1003503 pubmed publisher
Wilkinson A, Ballabio E, Geng H, North P, Tapia M, Kerry J, et al. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Rep. 2013;3:116-27 pubmed publisher
product information
SKU :
5030S
Product-Name :
MEF2C (D80C1) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50-60
Host :
Rabbit
Target :
MEF2C
Primary-Protein :
MEF2C
Alt-Names :
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C),MEF2C,Myocyte-specific enhancer factor 2C,myocyte enhancer factor 2C
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.