product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Sox2 (D6D9) XP® Rabbit mAb (ChIP Formulated)
catalog :
5024
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D6D9
reactivity :
human, mouse, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Cell Signaling Technology product webpage
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:400; fig 2
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1e
Balboa D, Weltner J, Eurola S, Trokovic R, Wartiovaara K, Otonkoski T. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation. Stem Cell Reports. 2015;5:448-59 pubmed publisher
  • immunohistochemistry; dog; 1:50; fig 2
Kegler K, Spitzbarth I, Imbschweiler I, Wewetzer K, Baumgärtner W, Seehusen F. Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation. PLoS ONE. 2015;10:e0133916 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s4d
Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo M, Berno V, et al. The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma. Oncotarget. 2015;6:17514-31 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
Weissferdt A, Rodriguez Canales J, Liu H, Fujimoto J, Wistuba I, Moran C. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015;46:376-83 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000
Holmberg Olausson K, Maire C, Haidar S, Ling J, Learner E, Nistér M, et al. Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas. PLoS ONE. 2014;9:e106694 pubmed publisher
  • western blot; human; 1:1000; fig 1c
Mouallif M, Albert A, Zeddou M, Ennaji M, Delvenne P, Guenin S. Expression profile of undifferentiated cell transcription factor 1 in normal and cancerous human epithelia. Int J Exp Pathol. 2014;95:251-9 pubmed publisher
Wu C, Zhang H, Gupta N, Alshareef A, Wang Q, Huang Y, et al. A positive feedback loop involving the Wnt/?-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. J Hematol Oncol. 2016;9:120 pubmed
Emani M, Närvä E, Stubb A, Chakroborty D, Viitala M, Rokka A, et al. The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency. Stem Cell Reports. 2015;4:519-28 pubmed publisher
Wang S, Tie J, Wang R, Hu F, Gao L, Wang W, et al. SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN. Cancer Lett. 2015;358:210-9 pubmed publisher
Miyatake Y, Sheehy N, Ikeshita S, Hall W, Kasahara M. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like ATL cells in an NF-κB- and vimentin-dependent manner. Cancer Lett. 2015;357:355-63 pubmed publisher
Rybak A, Tang D. SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cell Signal. 2013;25:2734-42 pubmed publisher
Bareiss P, Paczulla A, Wang H, Schairer R, Wiehr S, Kohlhofer U, et al. SOX2 expression associates with stem cell state in human ovarian carcinoma. Cancer Res. 2013;73:5544-55 pubmed publisher
da Cunha J, da Costa Neves A, Kerkis I, da Silva M. Pluripotent stem cell transcription factors during human odontogenesis. Cell Tissue Res. 2013;353:435-41 pubmed publisher
Kregel S, Kiriluk K, Rosen A, Cai Y, Reyes E, Otto K, et al. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. PLoS ONE. 2013;8:e53701 pubmed publisher
Anaka M, Freyer C, Gedye C, Caballero O, Davis I, Behren A, et al. Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile. Stem Cells. 2012;30:336-43 pubmed publisher
product information
SKU :
5024S
Product-Name :
Sox2 (D6D9) XP® Rabbit mAb (ChIP Formulated)
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, (Mk, B, Dg, Hr)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Sox2
Primary-Protein :
SOX2
Alt-Names :
ANOP3,MCOPS3,MGC2413,SOX2,SRY (sex determining region Y)-box 2,SRY-related HMG-box gene 2,Transcription factor SOX-2,transcription factor SOX2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.