product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ASH2L (D93F6) XP® Rabbit mAb
catalog :
5019
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D93F6
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1j
Lüscher Firzlaff J, Chatain N, Kuo C, Braunschweig T, Bochynska A, Ullius A, et al. Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l. Sci Rep. 2019;9:8262 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Ishiuchi T, Ohishi H, Sato T, Kamimura S, Yorino M, Abe S, et al. Zfp281 Shapes the Transcriptome of Trophoblast Stem Cells and Is Essential for Placental Development. Cell Rep. 2019;27:1742-1754.e6 pubmed publisher
  • western blot; human; loading ...; fig s1f
Zhao Z, Wang L, Volk A, Birch N, Stoltz K, Bartom E, et al. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes Dev. 2019;33:61-74 pubmed publisher
  • western blot; human; fig 5d
Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed publisher
  • western blot; human; loading ...; fig 1a
Butler J, Qiu Y, Zhang N, Yoo S, Coombes K, Dent S, et al. Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia. Leuk Lymphoma. 2017;58:1207-1218 pubmed publisher
Constantin D, Widmann C. ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin's lymphoma and testicular cancer cells. Cell Death Dis. 2020;11:1019 pubmed publisher
Rudra D, deRoos P, Chaudhry A, Niec R, Arvey A, Samstein R, et al. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol. 2012;13:1010-9 pubmed publisher
product information
SKU :
5019S
Product-Name :
ASH2L (D93F6) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk, (Dm)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
80, 65
Host :
Rabbit
Target :
ASH2L
Primary-Protein :
ASH2L
Alt-Names :
ASH2,ASH2-like protein,ASH2L,ASH2L1,ASH2L2,Bre2,Set1/Ash2 histone methyltransferase complex subunit ASH2,ash2 (absent, small, or homeotic)-like (Drosophila)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.