product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-AMPKα (Thr172)
catalog :
50081
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D4D6D
reactivity :
human, mouse, rat, thale cress
application :
western blot, immunohistochemistry
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; thale cress; fig 5c
Minton D, Elliehausen C, Javors M, Santangello K, Konopka A. Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis. Arthritis Res Ther. 2021;23:253 pubmed publisher
  • western blot; human; loading ...; fig 6d
Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher
  • western blot; human; 1:1000; fig 1c
Tang X, Li G, Shi L, Su F, Qian M, Liu Z, et al. Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis. Nat Commun. 2021;12:5058 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3b
Shi Y, Hou S. Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4. Mol Med Rep. 2021;24: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Wang X, Lu Y, Tuo Z, Zhou H, Zhang Y, Cao Z, et al. Role of SIRT1/AMPK signaling in the proliferation, migration and invasion of renal cell carcinoma cells. Oncol Rep. 2021;45: pubmed publisher
  • western blot; mouse; loading ...; fig 5c
Dong W, Zhang H, Zhao C, Luo Y, Chen Y. Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway. Front Physiol. 2021;12:624989 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5b
  • western blot; mouse; loading ...; fig 5a
Li M, Li C, Ye Z, Huang J, Li Y, Lai W, et al. Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice. J Cell Mol Med. 2020;24:5109-5121 pubmed publisher
  • western blot; rat; 1:2000; loading ...; fig 5a
Garc a Arroyo F, Monroy S nchez F, Mu oz Jim nez I, Gonzaga G, Andr s Hernando A, Zazueta C, et al. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; loading ...; fig 5e
Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6a, 6d
Liu M, Yin L, Li W, Hu J, Wang H, Ye B, et al. C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction. J Cell Physiol. 2019;234:18731-18747 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Shao J, Miao C, Geng Z, Gu M, Wu Y, Li Q. Effect of eNOS on Ischemic Postconditioning-Induced Autophagy against Ischemia/Reperfusion Injury in Mice. Biomed Res Int. 2019;2019:5201014 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
  • western blot; rat; loading ...; fig 8b
Chen C, Zou L, Lin Q, Yan X, Bi H, Xie X, et al. Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload. Redox Biol. 2019;20:390-401 pubmed publisher
Yin J, Wang X, Ge X, Ding F, Shi Z, Ge Z, et al. Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas. Nat Commun. 2023;14:5913 pubmed publisher
Tian R, Yang J, Wang X, Liu S, Dong R, Wang Z, et al. Honokiol acts as an AMPK complex agonist therapeutic in non-alcoholic fatty liver disease and metabolic syndrome. Chin Med. 2023;18:30 pubmed publisher
Liu D, Ma Z, Xu L, Zhang X, Qiao S, Yuan J. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades. Aging (Albany NY). 2019;11:10061-10073 pubmed publisher
Li F, Yang C, Zhang H, Ma J, Jia J, Tang X, et al. BET inhibitor JQ1 suppresses cell proliferation via inducing autophagy and activating LKB1/AMPK in bladder cancer cells. Cancer Med. 2019;: pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.