product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NIK Antibody
catalog :
4994
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, western blot knockout validation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig e3a
  • western blot knockout validation; human; loading ...; fig 2d, e9a
Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed publisher
  • western blot knockout validation; mouse; fig s6i
Zhao P, Wong K, Sun X, Reilly S, Uhm M, Liao Z, et al. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 2018;172:731-743.e12 pubmed publisher
  • western blot knockout validation; mouse; 1:500; fig s3d
  • western blot; human; 1:500; loading ...; fig s3c
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher
  • western blot knockout validation; human; fig 1
  • immunocytochemistry; mouse; fig 1
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
  • western blot; human; fig 1
  • western blot knockout validation; mouse; fig s8
Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 3d
Fry C, Nayeem S, Dillon E, Sarkar P, Tumurbaatar B, Urban R, et al. Glucocorticoids increase skeletal muscle NF-?B inducing kinase (NIK): links to muscle atrophy. Physiol Rep. 2016;4: pubmed
  • western blot; mouse; loading ...; fig 3d
Zhou Y, Xu H, Ding Y, Lu Q, Zou M, Song P. AMPK?1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2. Oncotarget. 2016;7:53654-53667 pubmed publisher
  • western blot; human; fig 2
Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed publisher
Vazquez Santillan K, Melendez Zajgla J, Jimenez Hernandez L, Gaytan Cervantes J, Muñoz Galindo L, Pina Sanchez P, et al. NF-kappa?-inducing kinase regulates stem cell phenotype in breast cancer. Sci Rep. 2016;6:37340 pubmed publisher
product information
SKU :
4994P
Product-Name :
NIK Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, (R, Mk, B, Hr)
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
125
Host :
Rabbit
Target :
NIK
Primary-Protein :
Nik
Alt-Names :
FTDCR1B,HS,HsNIK,M3K14,MAP3K14,Mitogen-activated protein kinase kinase kinase 14,NF-kappa-beta-inducing kinase,NIK,Serine/threonine-protein kinase NIK,serine/threonine protein-kinase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.