product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-VEGF Receptor 2 (Tyr951) (15D2) Rabbit mAb
catalog :
4991
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
15D2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 1
Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed publisher
  • western blot; human
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  • western blot; human
Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
  • western blot; human
Fuchs K, Bize P, Dormond O, Denys A, Doelker E, Borchard G, et al. Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model. J Vasc Interv Radiol. 2014;25:379-87, 387.e1-2 pubmed publisher
Kim M, Kino oka M. Switching between self-renewal and lineage commitment of human induced pluripotent stem cells via cell-substrate and cell-cell interactions on a dendrimer-immobilized surface. Biomaterials. 2014;35:5670-8 pubmed publisher
Huveldt D, Lewis Tuffin L, Carlson B, Schroeder M, Rodriguez F, Giannini C, et al. Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion. PLoS ONE. 2013;8:e56505 pubmed publisher
Akiyama K, Ohga N, Hida Y, Kawamoto T, Sadamoto Y, Ishikawa S, et al. Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment. Am J Pathol. 2012;180:1283-93 pubmed publisher
Dellinger M, Brekken R. Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. PLoS ONE. 2011;6:e28947 pubmed publisher
product information
SKU :
4991S
Product-Name :
Phospho-VEGF Receptor 2 (Tyr951) (15D2) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
230
Host :
Rabbit
Target :
VEGFR2 (Tyr951) phosphate
Primary-Protein :
VEGFR-2
Alt-Names :
CD309,FLK-1,FLK1,Fetal liver kinase 1,KDR,Kinase insert domain receptor,Protein-tyrosine kinase receptor flk-1,VEGFR,VEGFR-2,VEGFR2,VGFR2,Vascular endothelial growth factor receptor 2,fetal liver kinase-1,kinase insert domain receptor (a type III receptor tyrosine kinase),soluble VEGFR2,tyrosine kinase growth factor receptor
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.