product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Actin (13E5) Rabbit mAb
catalog :
4970
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
13E5
reactivity :
African green monkey, human, mouse, rat, dogs, bovine, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, proximity ligation assay
citations: 386
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2b
Shen C, Hsieh C, Jiang K, Lin C, Chiang N, Li T, et al. AUY922 induces retinal toxicity through attenuating TRPM1. J Biomed Sci. 2021;28:55 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 2a
Guo Y, Liu B, Liu Y, Sun W, Gao W, Mao S, et al. Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma. Front Cell Dev Biol. 2021;9:690796 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 7b
Lu J, Wang W, Li P, Wang X, Gao C, Zhang B, et al. MiR-146a regulates regulatory T cells to suppress heart transplant rejection in mice. Cell Death Discov. 2021;7:165 pubmed publisher
  • western blot; mouse; loading ...; fig 6d
Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee S, Keerthikumar S, et al. Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis. Nat Commun. 2021;12:3950 pubmed publisher
  • western blot; mouse; 1:1500; loading ...; fig 5e
Tian X, Wang Y, Lu Y, Wang W, Du J, Chen S, et al. Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19. Cell Death Dis. 2021;12:646 pubmed publisher
  • western blot; mouse; loading ...; fig 1d
Kim C, Jin J, Ye Z, Jadhav R, Gustafson C, Hu B, et al. Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021;131: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s1a
Warwick T, Schulz M, Günther S, Gilsbach R, Neme A, Carlberg C, et al. A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes. Sci Rep. 2021;11:6518 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3g
Ben Sasson A, Watson J, Sheffler W, Johnson M, Bittleston A, Somasundaram L, et al. Design of biologically active binary protein 2D materials. Nature. 2021;589:468-473 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6c
Kushioka J, Kaito T, Okada R, Ishiguro H, Bal Z, Kodama J, et al. A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone. Bone Res. 2020;8:41 pubmed publisher
  • western blot; mouse; loading ...; fig 5c
Hu Q, Lu Y, Hu F, He S, Xu X, Niu Y, et al. Resistant dextrin reduces obesity and attenuates adipose tissue inflammation in high-fat diet-fed mice. Int J Med Sci. 2020;17:2611-2621 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s3-1a
Ded L, Hwang J, Miki K, Shi H, Chung J. 3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice. elife. 2020;9: pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Panic V, Pearson S, Banks J, Tippetts T, Velasco Silva J, Lee S, et al. Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. elife. 2020;9: pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Jiao T, Yao X, Zhao Y, Zhou Y, Gao Y, Fan S, et al. Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation. Drug Metab Dispos. 2020;48:830-839 pubmed publisher
  • western blot; mouse; 1:2000; loading ...
Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Alexander R, Liou Y, Knudsen N, Starost K, Xu C, Hyde A, et al. Bmal1 integrates mitochondrial metabolism and macrophage activation. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 1b
Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, et al. JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Cell Death Differ. 2020;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1j
Wei Y, Lu M, Mei M, Wang H, Han Z, Chen M, et al. Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection. Nat Commun. 2020;11:941 pubmed publisher
  • western blot; human; fig 1b
  • western blot; mouse; loading ...; fig 1c
Wang H, Chen B, Lin Y, Zhou Y, Li X. Legumain Promotes Gastric Cancer Progression Through Tumor-associated Macrophages In vitro and In vivo. Int J Biol Sci. 2020;16:172-180 pubmed publisher
  • western blot; rat; 1:50; loading ...; fig 4g
Presby D, Checkley L, Jackman M, Higgins J, Jones K, Giles E, et al. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019;317:R684-R695 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Robinson M, Maximov V, Lallani S, Farooq H, Taylor M, Read R, et al. Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma. Sci Rep. 2019;9:13611 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Jiao X, Ye J, Wang X, Yin X, Zhang G, Cheng X. KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT). Med Sci Monit. 2019;25:6788-6796 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Liu H, Muhammad T, Guo Y, Li M, Sha Q, Zhang C, et al. RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019;6:1900295 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Ho P, Leung C, Liu H, Pang S, Lam C, Xian J, et al. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). Autophagy. 2019;:1-24 pubmed publisher
  • western blot; human; fig s4a
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed publisher
  • western blot; mouse; loading ...; fig ex8i
McAlpine C, Kiss M, Rattik S, He S, Vassalli A, Valet C, et al. Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. 2019;566:383-387 pubmed publisher
  • western blot; mouse; loading ...; fig 6c
Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
  • western blot; mouse; loading ...; fig s2e
Sanin D, Matsushita M, Klein Geltink R, Grzes K, van Teijlingen Bakker N, Corrado M, et al. Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2. Immunity. 2018;49:1021-1033.e6 pubmed publisher
  • western blot; human; loading ...; fig 2c
Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  • western blot; human; 1:10,000; loading ...; fig 2d
Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Guerrini V, Prideaux B, Blanc L, Bruiners N, Arrigucci R, Singh S, et al. Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific. PLoS Pathog. 2018;14:e1007223 pubmed publisher
  • western blot; mouse; loading ...; fig 7b
Xu Y, Xu J, Ge K, Tian Q, Zhao P, Guo Y. Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice. Int J Biol Macromol. 2018;118:365-374 pubmed publisher
  • western blot; human; loading ...; fig 2b
Dai L, Del Valle L, Miley W, Whitby D, Ochoa A, Flemington E, et al. Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi's sarcoma development. Oncogene. 2018;37:4534-4545 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1a
Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, et al. Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1. Nat Commun. 2016;7:12756 pubmed publisher
  • western blot; pigs ; 1:2000; fig 2A
Springler A, Hessenberger S, Schatzmayr G, Mayer E. Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel). 2016;8: pubmed publisher
  • western blot; human; fig 1
Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher
  • western blot; mouse; 1:5000; fig 4
Villa M, Crotta S, Dingwell K, Hirst E, Gialitakis M, Ahlfors H, et al. The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. 2016;7:12652 pubmed publisher
  • western blot; human; 1:1000; fig 1
Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  • western blot; human; 1:1000; fig 6
Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, et al. MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network. Stem Cell Reports. 2016;7:236-48 pubmed publisher
  • western blot; human; 1:1000; fig 3
Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed
  • western blot; rat; 1:1000; fig 3
Zhang Y, Lin R, Tao J, Wu Y, Chen B, Yu K, et al. Electroacupuncture improves cognitive ability following cerebral ischemia reperfusion injury via CaM-CaMKIV-CREB signaling in the rat hippocampus. Exp Ther Med. 2016;12:777-782 pubmed
  • western blot; African green monkey; fig 2
Brunnemann A, Liermann K, Deinhardt Emmer S, Maschkowitz G, Pohlmann A, Sodeik B, et al. Recombinant herpes simplex virus type 1 strains with targeted mutations relevant for aciclovir susceptibility. Sci Rep. 2016;6:29903 pubmed publisher
  • western blot; mouse; 1:200; fig 1
Yuan Y, Ren Y, Yuan P, Yan L, Qiao J. TRAIP is involved in chromosome alignment and SAC regulation in mouse oocyte meiosis. Sci Rep. 2016;6:29735 pubmed publisher
  • western blot; rat; 1:1000
Arsenijevic D, Cajot J, Fellay B, Dulloo A, Van Vliet B, Montani J. Uninephrectomy-Induced Lipolysis and Low-Grade Inflammation Are Mimicked by Unilateral Renal Denervation. Front Physiol. 2016;7:227 pubmed publisher
  • western blot; mouse; fig 1
Zhao W, Li A, Feng X, Hou T, Liu K, Liu B, et al. Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cell Signal. 2016;28:1401-11 pubmed publisher
  • western blot; human; 1:1000; fig 1
Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher
  • western blot; human; fig 4
Li Q, Karim A, Ding X, Das B, Dobrowolski C, Gibson R, et al. Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis. Sci Rep. 2016;6:27566 pubmed publisher
  • western blot; human; 1:5000; fig 4
Kochan J, Wawro M, Kasza A. IF-combined smRNA FISH reveals interaction of MCPIP1 protein with IER3 mRNA. Biol Open. 2016;5:889-98 pubmed publisher
  • western blot; human; fig 5
Jia Y, Zhao J, Liu M, Li B, Song Y, Li Y, et al. Brazilin exerts protective effects against renal ischemia-reperfusion injury by inhibiting the NF-?B signaling pathway. Int J Mol Med. 2016;38:210-6 pubmed publisher
  • western blot; bovine; 1:1000; fig 4
Lin Y, Sun X, Hou X, Qu B, Gao X, Li Q. Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow. BMC Vet Res. 2016;12:81 pubmed publisher
  • western blot; African green monkey; 1:1000; fig s2
  • western blot; mouse; 1:1000; fig 1
Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
  • western blot; human; fig 1
Josipovic I, Fork C, Preussner J, Prior K, Iloska D, Vasconez A, et al. PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells. Acta Physiol (Oxf). 2016;218:13-27 pubmed publisher
  • western blot; mouse; fig 5
Qin Y, Wang Q, Zhou Y, Duan Y, Gao Q. Inhibition of IFN-?-Induced Nitric Oxide Dependent Antimycobacterial Activity by miR-155 and C/EBP?. Int J Mol Sci. 2016;17:535 pubmed publisher
  • western blot; human; 1:1000; fig s5
  • western blot; mouse; 1:1000; fig 2
Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, et al. A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. Cell Death Differ. 2016;23:1380-93 pubmed publisher
  • western blot; human; 1:1000; fig 4
Jung Y, Decker A, Wang J, Lee E, Kana L, Yumoto K, et al. Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow. Oncotarget. 2016;7:25698-711 pubmed publisher
  • western blot; human; 1:1000; fig 1
Angeloni N, McMahon K, Swaminathan S, Plebanek M, Osman I, Volpert O, et al. Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1. Sci Rep. 2016;6:22915 pubmed publisher
  • western blot; mouse; 1:500; fig 2
Ramani M, Mylvaganam S, Krawczyk M, Wang L, Zoidl C, Brien J, et al. Differential expression of astrocytic connexins in a mouse model of prenatal alcohol exposure. Neurobiol Dis. 2016;91:83-93 pubmed publisher
  • western blot; human; 1:1000; fig 3h
Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
  • western blot; mouse; 1:10,000; fig 1
Kabra D, Pfuhlmann K, García Cáceres C, Schriever S, Casquero García V, Kebede A, et al. Hypothalamic leptin action is mediated by histone deacetylase 5. Nat Commun. 2016;7:10782 pubmed publisher
  • western blot; human; 1:1000; fig 1
Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher
  • western blot; human; fig 1c
Randles L, Anchoori R, Roden R, Walters K. The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression. J Biol Chem. 2016;291:8773-83 pubmed publisher
  • western blot; mouse; fig 8
  • western blot; human; fig 4
Shukla S, Sinha S, Khan S, Kumar S, Singh K, Mitra K, et al. Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. Sci Rep. 2016;6:21860 pubmed publisher
  • western blot; human; 1:2000; fig 2
Gao S, Chen X, Jin H, Ren S, Liu Z, Fang X, et al. Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. Oncol Lett. 2016;11:1567-1573 pubmed
  • western blot; mouse; 1:2500; fig s3
White Y, Bagchi A, Van Ziffle J, Inguva A, Bollag G, Zhang C, et al. KRAS insertion mutations are oncogenic and exhibit distinct functional properties. Nat Commun. 2016;7:10647 pubmed publisher
  • western blot; human; fig 1
Cao K, Gong H, Qiu Z, Wen Q, Zhang B, Tang T, et al. Hepatitis B virus X protein reduces the stability of Nrdp1 to up-regulate ErbB3 in hepatocellular carcinoma cells. Tumour Biol. 2016;37:10375-82 pubmed publisher
  • western blot; rat; 1:5000; fig 4
Wu C, Chou H, Huang L, Lin Y, Chen C. Bubble CPAP Support after Discontinuation of Mechanical Ventilation Protects Rat Lungs with Ventilator-Induced Lung Injury. Respiration. 2016;91:171-9 pubmed publisher
  • western blot; mouse; fig 1b
Kao S, Soares V, Kristiansen A, Stankovic K. Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear. Aging Cell. 2016;15:301-8 pubmed publisher
  • western blot; human; fig s2
Oda S, Nozawa T, Nozawa Minowa A, Tanaka M, Aikawa C, Harada H, et al. Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes. PLoS ONE. 2016;11:e0147061 pubmed publisher
  • western blot; human; 1:5000; fig 1
Qiu Z, Sun R, Mo X, Li W. The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth. PLoS ONE. 2016;11:e0147185 pubmed publisher
  • western blot; mouse; 1:1000
Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4e
Lin R, Chen J, Li X, Mao J, Wu Y, Zhuo P, et al. Electroacupuncture at the Baihui acupoint alleviates cognitive impairment and exerts neuroprotective effects by modulating the expression and processing of brain-derived neurotrophic factor in APP/PS1 transgenic mice. Mol Med Rep. 2016;13:1611-7 pubmed publisher
  • proximity ligation assay; human; 1:200; loading ...; fig 6a
Wong H, Wang G, Croessmann S, Zabransky D, Chu D, Garay J, et al. TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer. Oncotarget. 2015;6:44927-40 pubmed publisher
  • western blot; human; fig 5
Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed publisher
  • western blot; mouse; 1:10,000; fig 6
Tarangelo A, Lo N, Teng R, Kim E, Le L, Watson D, et al. Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Nat Commun. 2015;6:10028 pubmed publisher
  • western blot; human; fig 2
Wu Y, Wang L, Bao H, Zou S, Fu C, Gong H, et al. Nrdp1S, short variant of Nrdp1, inhibits human glioma progression by increasing Nrdp1-mediated ErbB3 ubiquitination and degradation. J Cell Mol Med. 2016;20:422-9 pubmed publisher
  • western blot; human; fig 1b
Freischmidt A, Schöpflin M, Feiler M, Fleck A, Ludolph A, Weishaupt J. Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton. BMC Neurosci. 2015;16:77 pubmed publisher
  • western blot; dogs; 1:1000; fig 5
Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher
  • western blot; mouse; fig 6
Ramiscal R, Parish I, Lee Young R, Babon J, Blagih J, Pratama A, et al. Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation. elife. 2015;4: pubmed publisher
  • western blot; human; fig 1c
Mizuno S, Hanamura I, Ota A, Karnan S, Narita T, Ri M, et al. Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells. Int J Hematol. 2015;102:569-78 pubmed publisher
  • western blot; human; 1:5000; fig 3
O Leary K, Shia A, Cavicchioli F, Haley V, Comino A, Merlano M, et al. Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer. Br J Cancer. 2015;113:970-8 pubmed publisher
  • western blot; mouse
Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher
  • western blot; mouse
Qu D, Weygant N, May R, Chandrakesan P, Madhoun M, Ali N, et al. Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. PLoS ONE. 2015;10:e0134212 pubmed publisher
  • western blot; human
Kao S, Stankovic K. Transactivation of human osteoprotegerin promoter by GATA-3. Sci Rep. 2015;5:12479 pubmed publisher
  • western blot; mouse; 1:1000; fig 7a
He C, Medley S, Hu T, Hinsdale M, Lupu F, Virmani R, et al. PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun. 2015;6:7770 pubmed publisher
  • western blot; African green monkey; fig 3a
Lee Y, Chun S, Kim K. Sumoylation controls CLOCK-BMAL1-mediated clock resetting via CBP recruitment in nuclear transcriptional foci. Biochim Biophys Acta. 2015;1853:2697-708 pubmed publisher
  • western blot; human; fig 3
Zhu S, Chen Z, Katsha A, Hong J, Belkhiri A, el Rifai W. Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. Oncogene. 2016;35:1847-56 pubmed publisher
  • western blot; human; fig 4
Shan C, Lin J, Hou J, Liu H, Chen S, Chen A, et al. Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule. Nucleic Acids Res. 2015;43:6677-91 pubmed publisher
  • western blot; human; 1:1000; fig s4
Adoro S, Cubillos Ruiz J, Chen X, Deruaz M, Vrbanac V, Song M, et al. IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. Nat Commun. 2015;6:7562 pubmed publisher
  • western blot; human; fig 6
Zhang T, Zhou Q, Ogmundsdottir M, Möller K, Siddaway R, Larue L, et al. Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1. J Cell Sci. 2015;128:2938-50 pubmed publisher
  • western blot; human; fig 1
Kawamura N, Nimura K, Nagano H, Yamaguchi S, Nonomura N, Kaneda Y. CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells. Oncotarget. 2015;6:22361-74 pubmed
  • western blot; human
Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • western blot; mouse; fig 2b
Kataoka K, Matsumoto H, Kaneko H, Notomi S, Takeuchi K, Sweigard J, et al. Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death. Cell Death Dis. 2015;6:e1731 pubmed publisher
  • western blot; rat
Park Y, Liu C, Luo T, Dietrich W, Bramlett H, Hu B. Chaperone-Mediated Autophagy after Traumatic Brain Injury. J Neurotrauma. 2015;32:1449-57 pubmed publisher
  • western blot; human; 1:1000; fig 6
Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, et al. Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-κB-Snail signaling in glioma. Cancer Biol Ther. 2015;16:898-911 pubmed publisher
  • western blot; mouse; loading ...; fig s9b
Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed publisher
  • western blot; human; 1:1000; fig s4e
Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015;18:631-6 pubmed publisher
  • western blot; mouse; 1:1000; fig 4a
Zheng T, Yang X, Wu D, Xing S, Bian F, Li W, et al. Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway. Br J Pharmacol. 2015;172:3284-301 pubmed publisher
  • western blot; mouse; 1:2000; fig 5
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
  • western blot; mouse; fig 1,2,3,4
Bryant J, Donahue G, Wang X, Meyer Ficca M, Luense L, Weller A, et al. Characterization of BRD4 during mammalian postmeiotic sperm development. Mol Cell Biol. 2015;35:1433-48 pubmed publisher
  • western blot; human; fig 3
Gong X, Yi J, Carmon K, Crumbley C, Xiong W, Thomas A, et al. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. 2015;34:4692-701 pubmed publisher
  • western blot; human; fig 6
Ye S, Lowther S, Stambas J. Inhibition of reactive oxygen species production ameliorates inflammation induced by influenza A viruses via upregulation of SOCS1 and SOCS3. J Virol. 2015;89:2672-83 pubmed publisher
  • western blot; rat; 1:2000; fig 7
Ta M, Rao P, Korgaonkar M, Foster S, Peduto A, Harris D, et al. Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease. Physiol Rep. 2014;2: pubmed publisher
  • western blot; human; 1:5000
Shukla M, Htoo H, Wintachai P, Hernandez J, Dubois C, Postina R, et al. Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17. J Pineal Res. 2015;58:151-65 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 3a
Chen X, Yammine S, Shi C, Tark Dame M, Göndör A, Ohlsson R. The visualization of large organized chromatin domains enriched in the H3K9me2 mark within a single chromosome in a single cell. Epigenetics. 2014;9:1439-45 pubmed publisher
  • western blot; human; 1:1000
Shi L, Zhang B, Sun X, Lu S, Liu Z, Liu Y, et al. MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1. Br J Cancer. 2014;111:2316-27 pubmed publisher
  • western blot; human
Yin Y, Zhang S, Luo H, Zhang X, Geng G, Li J, et al. Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance. J Biol Chem. 2015;290:35-45 pubmed publisher
  • western blot; mouse; fig 3
Das L, Rosenjack J, Au L, Galle P, Hansen M, Cathcart M, et al. Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency. J Invest Dermatol. 2015;135:389-399 pubmed publisher
  • western blot; mouse; 1:2000; fig 4
Morris S, Carter K, Baek J, Koszarek A, Yeh M, Knoblaugh S, et al. TGF-? signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene. 2015;34:3273-82 pubmed publisher
  • western blot; mouse; 1:500
Yan T, Li L, Sun B, Liu F, Yang P, Chen T, et al. Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice. PLoS ONE. 2014;9:e98981 pubmed publisher
  • western blot; human; 1:500
Malaviya A, Sylvester P. Synergistic Antiproliferative Effects of Combined ? -Tocotrienol and PPAR ? Antagonist Treatment Are Mediated through PPAR ? -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146 pubmed publisher
  • western blot; human
Fontebasso A, Papillon Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset P, et al. Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nat Genet. 2014;46:462-6 pubmed publisher
  • western blot; mouse
Caro Maldonado A, Wang R, Nichols A, Kuraoka M, Milasta S, Sun L, et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol. 2014;192:3626-36 pubmed publisher
  • western blot; rat; 1:1000
Mott N, Pinceti E, Rao Y, Przybycien Szymanska M, Prins S, Shults C, et al. Age-dependent Effects of 17?-estradiol on the dynamics of estrogen receptor ? (ER?) protein-protein interactions in the ventral hippocampus. Mol Cell Proteomics. 2014;13:760-79 pubmed publisher
  • western blot; mouse; 1:30,000
Qin Z, Kaufman R, Khoury R, Khoury M, Aswad D. Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent. PLoS ONE. 2013;8:e80758 pubmed publisher
  • western blot; human
Haas M, Onstead Haas L, Naem E, Arnold A, Rohrbaugh N, Flowers M, et al. The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells. Phytother Res. 2014;28:873-9 pubmed publisher
Guittard G, Dios Esponera A, Palmer D, Akpan I, Barr V, Manna A, et al. The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells. Sci Rep. 2018;8:5336 pubmed publisher
van der Veen A, Maillard P, Schmidt J, Lee S, Deddouche Grass S, Borg A, et al. The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells. EMBO J. 2018;37: pubmed publisher
Tan X, Banerjee P, Liu X, Yu J, Gibbons D, Wu P, et al. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network. J Clin Invest. 2018;128:1267-1282 pubmed publisher
Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers K, et al. Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling. Cell. 2018;172:106-120.e21 pubmed publisher
Berrout J, Kyriakopoulou E, Moparthi L, Hogea A, Berrout L, Ivan C, et al. TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p. Nat Commun. 2017;8:947 pubmed publisher
Zhou X, Geng L, Wang D, Yi H, Talmon G, Wang J. R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis. Cancer Res. 2017;77:6589-6602 pubmed publisher
Vierra N, Dadi P, Milian S, Dickerson M, Jordan K, Gilon P, et al. TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis. Sci Signal. 2017;10: pubmed publisher
Maiti S, Mondal S, Satyavarapu E, Mandal C. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation. Cell Death Dis. 2017;8:e2926 pubmed publisher
Lu X, Nowicka U, Sridharan V, Liu F, Randles L, Hymel D, et al. Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets. Nat Commun. 2017;8:15540 pubmed publisher
Wu K, Zhao Z, Ma J, Chen J, Peng J, Yang S, et al. Deregulation of miR-193b affects the growth of colon cancer cells via transforming growth factor-? and regulation of the SMAD3 pathway. Oncol Lett. 2017;13:2557-2562 pubmed publisher
Nakama T, Yoshida S, Ishikawa K, Kubo Y, Kobayashi Y, Zhou Y, et al. Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization. Mol Ther Nucleic Acids. 2017;6:279-289 pubmed publisher
Lei L, Chen C, Zhao J, Wang H, Guo M, Zhou Y, et al. Targeted Expression of miR-7 Operated by TTF-1 Promoter Inhibited the Growth of Human Lung Cancer through the NDUFA4 Pathway. Mol Ther Nucleic Acids. 2017;6:183-197 pubmed publisher
Ram R, Brasch H, Dunne J, Davis P, Tan S, Itinteang T. The Identification of Three Cancer Stem Cell Subpopulations within Moderately Differentiated Lip Squamous Cell Carcinoma. Front Surg. 2017;4:12 pubmed publisher
Yang Y, Luo P, Xu H, Dai S, Rao W, Peng C, et al. RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-?-Catenin Pathway in Glutamate Excitotoxicity Injury. Front Cell Neurosci. 2017;11:59 pubmed publisher
Midde N, Sinha N, Lukka P, Meibohm B, Kumar S. Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells. PLoS ONE. 2017;12:e0172628 pubmed publisher
Cai Y, Sun Z, Jia H, Luo H, Ye X, Wu Q, et al. Rpph1 Upregulates CDC42 Expression and Promotes Hippocampal Neuron Dendritic Spine Formation by Competing with miR-330-5p. Front Mol Neurosci. 2017;10:27 pubmed publisher
Cho J, Zhang Y, Park S, Joseph A, Han C, Park H, et al. Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance. Nat Commun. 2017;8:14477 pubmed publisher
Zhang S, Liu Y, Wang F, Qiang J, Liu P, Zhang J, et al. Ilexsaponin A attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. PLoS ONE. 2017;12:e0170984 pubmed publisher
Nyati K, Masuda K, Zaman M, Dubey P, Millrine D, Chalise J, et al. TLR4-induced NF-?B and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017;45:2687-2703 pubmed publisher
Onoda A, Takeda K, Umezawa M. Dose-dependent induction of astrocyte activation and reactive astrogliosis in mouse brain following maternal exposure to carbon black nanoparticle. Part Fibre Toxicol. 2017;14:4 pubmed publisher
Kim Y, Tian C, Kim J, Shin B, Choo O, Kim Y, et al. Autophagic flux, a possible mechanism for delayed gentamicin-induced ototoxicity. Sci Rep. 2017;7:41356 pubmed publisher
Yang H, Ju F, Guo X, Ma S, Wang L, Cheng B, et al. RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Sci Rep. 2017;7:41738 pubmed publisher
Zhang C, Yan J, Xiao Y, Shen Y, Wang J, Ge W, et al. Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers. Int J Mol Sci. 2017;18: pubmed publisher
Hyeon J, Kim S, Lee S, Lee J, An S, Lee M, et al. Anti-Prion Screening for Acridine, Dextran, and Tannic Acid using Real Time-Quaking Induced Conversion: A Comparison with PrPSc-Infected Cell Screening. PLoS ONE. 2017;12:e0170266 pubmed publisher
Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed publisher
Tschurtschenthaler M, Adolph T, Ashcroft J, Niederreiter L, Bharti R, Saveljeva S, et al. Defective ATG16L1-mediated removal of IRE1? drives Crohn's disease-like ileitis. J Exp Med. 2017;214:401-422 pubmed publisher
Sun W, Chun J, Kim D, Ahn J, Kim M, Hwang I, et al. Molecular cloning and characterization of porcine ribosomal protein L21. J Vet Sci. 2017;18:531-540 pubmed publisher
Morii M, Kubota S, Honda T, Yuki R, Morinaga T, Kuga T, et al. Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. J Biol Chem. 2017;292:1648-1665 pubmed publisher
Zandvakili I, Lin Y, Morris J, Zheng Y. Rho GTPases: Anti- or pro-neoplastic targets?. Oncogene. 2017;36:3213-3222 pubmed publisher
Tang Z, Li J, Shen Q, Feng J, Liu H, Wang W, et al. Contribution of upregulated dipeptidyl peptidase 9 (DPP9) in promoting tumoregenicity, metastasis and the prediction of poor prognosis in non-small cell lung cancer (NSCLC). Int J Cancer. 2017;140:1620-1632 pubmed publisher
Henry W, Laszewski T, Tsang T, Beca F, Beck A, McAllister S, et al. Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling. Cancer Res. 2017;77:790-801 pubmed publisher
Uo T, Dvinge H, Sprenger C, Bradley R, Nelson P, Plymate S. Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain. Oncogene. 2017;36:1440-1450 pubmed publisher
Liu Z, Cordoba Chacon J, Kineman R, Cronstein B, Muzumdar R, Gong Z, et al. Growth Hormone Control of Hepatic Lipid Metabolism. Diabetes. 2016;65:3598-3609 pubmed
Wen S, Ling Y, Yang W, Shen J, Li C, Deng W, et al. Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury. J Cell Mol Med. 2017;21:432-443 pubmed publisher
Rahman N, Ramos Espiritu L, Milner T, Buck J, Levin L. Soluble adenylyl cyclase is essential for proper lysosomal acidification. J Gen Physiol. 2016;148:325-39 pubmed publisher
Nozaki R, Kono T, Bochimoto H, Watanabe T, Oketani K, Sakamaki Y, et al. Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells. Oncotarget. 2016;7:70437-70446 pubmed publisher
BRADSHAW A, Wickremesekera A, Brasch H, Chibnall A, Davis P, Tan S, et al. Cancer Stem Cells in Glioblastoma Multiforme. Front Surg. 2016;3:48 pubmed publisher
Heulot M, Chevalier N, Puyal J, Margue C, Michel S, Kreis S, et al. The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget. 2016;7:64342-64359 pubmed publisher
Bailey S, Desai K, Kron K, Mazrooei P, Sinnott Armstrong N, Treloar A, et al. Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer. Nat Genet. 2016;48:1260-6 pubmed publisher
Zhang L, Ren F, Zhang X, Wang X, Shi H, Zhou L, et al. Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. Dis Model Mech. 2016;9:799-809 pubmed publisher
Aztopal N, Cevatemre B, Sarimahmut M, Ari F, Dere E, Ozel M, et al. Pelargonium quercetorum Agnew induces apoptosis without PARP or cytokeratin 18 cleavage in non-small cell lung cancer cell lines. Oncol Lett. 2016;12:1429-1437 pubmed
Xue Y, Meng X, Ma L, Yuan Z. Plumbagin exhibits an anti-proliferative effect in human osteosarcoma cells by downregulating FHL2 and interfering with Wnt/?-catenin signalling. Oncol Lett. 2016;12:1095-1100 pubmed
Blackburn P, Hickey R, Nace R, Giama N, Kraft D, Bordner A, et al. Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma. Hum Mutat. 2016;37:1097-105 pubmed publisher
Fehrenbach S, Novak D, Bernhardt M, Larribere L, Boukamp P, Umansky V, et al. Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage. Sci Rep. 2016;6:28891 pubmed publisher
Hornstein N, Torres D, Das Sharma S, Tang G, Canoll P, Sims P. Ligation-free ribosome profiling of cell type-specific translation in the brain. Genome Biol. 2016;17:149 pubmed publisher
Kohnz R, Roberts L, DeTomaso D, Bideyan L, Yan P, Bandyopadhyay S, et al. Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity. ACS Chem Biol. 2016;11:2131-9 pubmed publisher
Zhang T, Sui D, Hu J. Structural insights of ZIP4 extracellular domain critical for optimal zinc transport. Nat Commun. 2016;7:11979 pubmed publisher
Metheetrairut C, Adams B, Nallur S, Weidhaas J, Slack F. cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation. Oncogene. 2017;36:512-524 pubmed publisher
Wang H, Gao K, Wen K, Allen I, Li G, Zhang W, et al. Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. BMC Microbiol. 2016;16:109 pubmed publisher
Markó L, Szijártó I, Filipović M, Kaßmann M, Balogh A, Park J, et al. Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury. Sci Rep. 2016;6:27517 pubmed publisher
Kuo Y, Lin C, Shih C. Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor ? Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat-. Int J Mol Sci. 2016;17: pubmed publisher
Kuo Y, Lin C, Shih C, Yang C. Antcin K, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects via Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in Muscles. Evid Based Complement Alternat Med. 2016;2016:4867092 pubmed publisher
Polak A, Kiliszek P, Sewastianik T, Szydłowski M, Jabłońska E, Białopiotrowicz E, et al. MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy. PLoS ONE. 2016;11:e0155893 pubmed publisher
Xu D, Zhou P, Wang Y, Zhang L, Fu W, Ruan B, et al. Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway. Mol Cancer. 2016;15:40 pubmed publisher
Kobayashi Y, Yoshida S, Zhou Y, Nakama T, Ishikawa K, Arima M, et al. Tenascin-C promotes angiogenesis in fibrovascular membranes in eyes with proliferative diabetic retinopathy. Mol Vis. 2016;22:436-45 pubmed
Ding Y, Li Q, Xu Y, Chen Y, Deng Y, Zhi F, et al. Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice. PLoS ONE. 2016;11:e0154375 pubmed publisher
Qiang G, Kong H, Fang D, McCann M, Yang X, Du G, et al. The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation. Nat Commun. 2016;7:11378 pubmed publisher
Shi Y, Li Y, Huang C, Ying L, Xue J, Wu H, et al. Resveratrol enhances HBV replication through activating Sirt1-PGC-1?-PPAR? pathway. Sci Rep. 2016;6:24744 pubmed publisher
Zhou Y, Wang Q, Zhou H, Chen G. Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells. Acta Pharmacol Sin. 2016;37:580-8 pubmed publisher
Kaylan K, Ermilova V, Yada R, Underhill G. Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix. Sci Rep. 2016;6:23490 pubmed publisher
Ishizuka T, Kanmani P, Kobayashi H, Miyazaki A, Soma J, Suda Y, et al. Immunobiotic Bifidobacteria Strains Modulate Rotavirus Immune Response in Porcine Intestinal Epitheliocytes via Pattern Recognition Receptor Signaling. PLoS ONE. 2016;11:e0152416 pubmed publisher
Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher
Kagiya G, Ogawa R, Hyodo F, Yamashita K, Nakamura M, Ishii A, et al. Development of a real-time imaging system for hypoxic cell apoptosis. Mol Ther Methods Clin Dev. 2016;5:16009 pubmed publisher
Franks S, Jones R, Briah R, Murray P, Moorehead R. BMS-754807 is cytotoxic to non-small cell lung cancer cells and enhances the effects of platinum chemotherapeutics in the human lung cancer cell line A549. BMC Res Notes. 2016;9:134 pubmed publisher
Lee D, Wang Y, Kalaitzidis D, Ramachandran J, Eda H, Sykes D, et al. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. J Clin Invest. 2016;126:1300-10 pubmed publisher
Wood L, Cox N, Phelps C, Lai S, Poddar A, Talbot C, et al. Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome. Sci Rep. 2016;6:19857 pubmed publisher
Guo M, Wei J, Huang X, Zhou Y, Yan Y, Qin Q. JNK1 Derived from Orange-Spotted Grouper, Epinephelus coioides, Involving in the Evasion and Infection of Singapore Grouper Iridovirus (SGIV). Front Microbiol. 2016;7:121 pubmed publisher
Liśkiewicz A, Kasprowska D, Wojakowska A, Polański K, Lewin Kowalik J, Kotulska K, et al. Long-term High Fat Ketogenic Diet Promotes Renal Tumor Growth in a Rat Model of Tuberous Sclerosis. Sci Rep. 2016;6:21807 pubmed publisher
Mo X, Cao Q, Liang H, Liu J, Li H, Liu F. MicroRNA-610 suppresses the proliferation of human glioblastoma cells by repressing CCND2 and AKT3. Mol Med Rep. 2016;13:1961-6 pubmed publisher
Jiang Y, Yang S, Tao J, Lin Z, Ye X, You Y, et al. Opposing needling promotes behavior recovery and exerts neuroprotection via the cAMP/PKA/CREB signal transduction pathway in transient MCAO rats. Mol Med Rep. 2016;13:2060-70 pubmed publisher
Harvey L, Yin Y, Attarwala I, Begum G, Deng J, Yan H, et al. Administration of DHA Reduces Endoplasmic Reticulum Stress-Associated Inflammation and Alters Microglial or Macrophage Activation in Traumatic Brain Injury. ASN Neuro. 2015;7: pubmed publisher
Ta M, Liuwantara D, Rangan G. Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells. BMC Nephrol. 2015;16:212 pubmed publisher
Kimmey J, Huynh J, Weiss L, Park S, Kambal A, Debnath J, et al. Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection. Nature. 2015;528:565-9 pubmed publisher
Lu F, Liang Q, Abi Mosleh L, Das A, De Brabander J, Goldstein J, et al. Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection. elife. 2015;4: pubmed publisher
Young C, Arteaga C, Cook R. Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers. Breast Cancer Res. 2015;17:148 pubmed publisher
Kim Y, Byun S, Zhang Y, Seok S, Kemper B, Ma J, et al. Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2. Genome Biol. 2015;16:268 pubmed publisher
Zhang J, Bai Y, Huang L, Qi Y, Zhang Q, Li S, et al. Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration. Cell Death Dis. 2015;6:e1972 pubmed publisher
Zhao Y, Wang H, Li J, Chen B, Xia G, Zhang P, et al. Hippocampal mitogen-activated protein kinase activation is associated with intermittent hypoxia in a rat model of obstructive sleep apnea syndrome. Mol Med Rep. 2016;13:137-45 pubmed publisher
Zhu J, Wang S, Zhang W, Qiu J, Shan Y, Yang D, et al. Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network. Oncotarget. 2015;6:43819-30 pubmed publisher
Lee M, Oprea Ilies G, Saavedra H. Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis. Oncotarget. 2015;6:37316-34 pubmed publisher
Ikoma Seki K, Nakamura K, Morishita S, Ono T, Sugiyama K, Nishino H, et al. Role of LRP1 and ERK and cAMP Signaling Pathways in Lactoferrin-Induced Lipolysis in Mature Rat Adipocytes. PLoS ONE. 2015;10:e0141378 pubmed publisher
Bak D, Zhang E, Yi M, Kim D, Lim K, Kim J, et al. High ω3-polyunsaturated fatty acids in fat-1 mice prevent streptozotocin-induced Purkinje cell degeneration through BDNF-mediated autophagy. Sci Rep. 2015;5:15465 pubmed publisher
Yan J, Duan J, Wu X, Guo C, Yin Y, Zhu Y, et al. Total saponins from Aralia taibaiensis protect against myocardial ischemia/reperfusion injury through AMPK pathway. Int J Mol Med. 2015;36:1538-46 pubmed publisher
Xiong Y, Su H, Lv P, Ma Y, Wang S, Miao H, et al. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. Oncotarget. 2015;6:35625-35 pubmed publisher
Lin K, Ye H, Han B, Wang W, Wei P, He B, et al. Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma. Oncogene. 2016;35:3376-86 pubmed publisher
Hyeon J, Choi J, Kim S, Govindaraj R, Jam Hwang K, Lee Y, et al. Discovery of Novel Anti-prion Compounds Using In Silico and In Vitro Approaches. Sci Rep. 2015;5:14944 pubmed publisher
Wu L, Nguyen L, Zhou K, de Soysa T, Li L, Miller J, et al. Precise let-7 expression levels balance organ regeneration against tumor suppression. elife. 2015;4:e09431 pubmed publisher
Yamaguchi H, Kawazu M, Yasuda T, Soda M, Ueno T, Kojima S, et al. Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer. Cancer Sci. 2015;106:1687-92 pubmed publisher
Liu X, Liao W, Yuan Q, Ou Y, Huang J. TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells. Oncotarget. 2015;6:34309-20 pubmed publisher
Weber H, Leal P, Stein S, Kunkel H, García P, Bizama C, et al. Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice. Oncotarget. 2015;6:31877-88 pubmed publisher
Li Y, He X, Yang X, Huang K, Luo Y, Zhu L, et al. Zinc inhibits the reproductive toxicity of Zearalenone in immortalized murine ovarian granular KK-1 cells. Sci Rep. 2015;5:14277 pubmed publisher
Kim Y, Chen C, Bolton E. Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells. PLoS ONE. 2015;10:e0138286 pubmed publisher
Tanaka T, Terai Y, Kogata Y, Ashihara K, Maeda K, Fujiwara S, et al. CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer. Oncol Rep. 2015;34:2282-8 pubmed publisher
Zuckermann A, La Ragione R, Baines D, Williams R. Valproic acid protects against haemorrhagic shock-induced signalling changes via PPARγ activation in an in vitro model. Br J Pharmacol. 2015;172:5306-17 pubmed publisher
Chen B, Tao J, Lin Y, Lin R, Liu W, Chen L. Electro-acupuncture exerts beneficial effects against cerebral ischemia and promotes the proliferation of neural progenitor cells in the cortical peri-infarct area through the Wnt/β-catenin signaling pathway. Int J Mol Med. 2015;36:1215-22 pubmed publisher
Oliveira T, Figueiredo C, Brito C, Stavroullakis A, Ferreira A, Nogueira Filho G, et al. Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway. Evid Based Complement Alternat Med. 2015;2015:704781 pubmed publisher
Zhu P, Yu H, Huang S, Xiang H, Li F, Zheng W. Synergistic effect of a tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 co‑expression vector on the proliferation of rat vascular smooth muscle cells. Mol Med Rep. 2015;12:5671-8 pubmed publisher
Yuan X, Chen H, Li X, Dai M, Zeng H, Shan L, et al. Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo. Sci Rep. 2015;5:12889 pubmed publisher
Yang F, Wang H, Jiang Z, Hu A, Chu L, Sun Y, et al. MicroRNA-19a mediates gastric carcinoma cell proliferation through the activation of nuclear factor-κB. Mol Med Rep. 2015;12:5780-6 pubmed publisher
Ismael Badarneh R, Guetta J, Klorin G, Berger G, Abu Saleh N, Abassi Z, et al. The Role of Angiotensin II and Cyclic AMP in Alveolar Active Sodium Transport. PLoS ONE. 2015;10:e0134175 pubmed publisher
Jaeger A, Fritschka S, Ponsuksili S, Wimmers K, Muráni E. Identification and Functional Characterization of Cis-Regulatory Elements Controlling Expression of the Porcine ADRB2 Gene. Int J Biol Sci. 2015;11:1006-15 pubmed publisher
Yang Y, Ni J, Hsu P, Mao J, Hsieh D, Xu A, et al. Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma. J Cell Mol Med. 2015;19:2385-96 pubmed publisher
Liu H, Ma Y, He H, Wang J, Jiang J, Shao R. SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells. Autophagy. 2015;11:2323-34 pubmed publisher
Arsenijevic D, Cajot J, Dulloo A, Montani J. Uninephrectomy in rats on a fixed food intake results in adipose tissue lipolysis implicating spleen cytokines. Front Physiol. 2015;6:195 pubmed publisher
Rapti K, Stillitano F, Karakikes I, Nonnenmacher M, Weber T, Hulot J, et al. Effectiveness of gene delivery systems for pluripotent and differentiated cells. Mol Ther Methods Clin Dev. 2015;2:14067 pubmed publisher
Foster K, Jane E, Premkumar D, Morales A, Pollack I. NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5. Int J Oncol. 2015;47:506-16 pubmed publisher
Jin D, Lee J, Kim K, Kim S, Kim D, Park J. Overexpression of MAPK15 in gastric cancer is associated with copy number gain and contributes to the stability of c-Jun. Oncotarget. 2015;6:20190-203 pubmed
Kagiya G, Ogawa R, Choudhuri R, Cook J, Hatashita M, Tanaka Y, et al. Selective enhancement of hypoxic cell killing by tempol-regulated suicide gene expression. Oncol Rep. 2015;34:1065-73 pubmed publisher
Theodosakis N, Held M, Marzuka Alcalá A, Meeth K, Micevic G, Long G, et al. BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume. Mol Cancer Ther. 2015;14:1680-92 pubmed publisher
Balla P, Maros M, Barna G, Antal I, Papp G, Sapi Z, et al. Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal cells in giant cell tumor of bone. PLoS ONE. 2015;10:e0125316 pubmed publisher
Nag S, Khan M, Samuel P, Ali Q, Hussain T. Chronic angiotensin AT2R activation prevents high-fat diet-induced adiposity and obesity in female mice independent of estrogen. Metabolism. 2015;64:814-25 pubmed publisher
Bakke S, Feng Y, Nikolić N, Kase E, Moro C, Stensrud C, et al. Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects. PLoS ONE. 2015;10:e0119556 pubmed publisher
Wang T, Huang B, Guo R, Ma J, Peng C, Zu X, et al. A let-7b binding site SNP in the 3'-UTR of the Bcl-xL gene enhances resistance to 5-fluorouracil and doxorubicin in breast cancer cells. Oncol Lett. 2015;9:1907-1911 pubmed
Aguilera Ã, González Sancho J, Zazo S, Rincón R, Fernández A, Tapia O, et al. Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. Oncotarget. 2015;6:5903-17 pubmed
Ohsaka A, Hirota Komatsu S, Araki M, Komatsu N. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. Biochem Biophys Res Commun. 2015;459:443-9 pubmed publisher
Chen Z, Luo H, Wang S, Xu J, Li J. Antiviral effects of Jinxin oral liquid against respiratory syncytial virus infection in the BALB/c mice model. J Ethnopharmacol. 2015;162:287-95 pubmed publisher
Huber R, Lucas J, Gomez Sarosi L, Coleman I, Zhao S, Coleman R, et al. DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance. Oncotarget. 2015;6:2134-47 pubmed
Flesner B, Kumar S, Bryan J. 6-Thioguanine and zebularine down-regulate DNMT1 and globally demethylate canine malignant lymphoid cells. BMC Vet Res. 2014;10:290 pubmed publisher
Ma F, Liu D. 17β-trenbolone, an anabolic-androgenic steroid as well as an environmental hormone, contributes to neurodegeneration. Toxicol Appl Pharmacol. 2015;282:68-76 pubmed publisher
Evison B, Actis M, Wu S, Shao Y, Heath R, Yang L, et al. A site-selective, irreversible inhibitor of the DNA replication auxiliary factor proliferating cell nuclear antigen (PCNA). Bioorg Med Chem. 2014;22:6333-43 pubmed publisher
Sun X, Lin Y, Huang Q, Shi J, Qiu L, Kang M, et al. Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection. J Cell Mol Med. 2015;19:581-94 pubmed publisher
Cho S, Cho M, Kim J, Kaeberlein M, Lee S, Suh Y. Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism. Oncotarget. 2015;6:43-55 pubmed
Futami J, Fujiyama H, Kinoshita R, Nonomura H, Honjo T, Tada H, et al. Denatured mammalian protein mixtures exhibit unusually high solubility in nucleic acid-free pure water. PLoS ONE. 2014;9:e113295 pubmed publisher
He B, Tao H, Liu S, Wei A. Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells. Mol Med Rep. 2015;11:1629-38 pubmed publisher
Matulic M, Skelin J, Radić Kristo D, Kardum Skelin I, Grcevic D, Antica M. Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry A. 2015;87:129-36 pubmed publisher
Cai M, Zhou Y, Zhou B, Lou S. Hypoxic conditioned medium from rat cerebral cortical cells enhances the proliferation and differentiation of neural stem cells mainly through PI3-K/Akt pathways. PLoS ONE. 2014;9:e111938 pubmed publisher
De Stefano D, Villella V, Esposito S, Tosco A, Sepe A, de Gregorio F, et al. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy. 2014;10:2053-74 pubmed publisher
Wacker I, Behrens J. Activin B antagonizes RhoA signaling to stimulate mesenchymal morphology and invasiveness of clear cell renal cell carcinomas. PLoS ONE. 2014;9:e111276 pubmed publisher
Blumenthal G, Gills J, Ballas M, Bernstein W, Komiya T, Dechowdhury R, et al. A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors. Oncotarget. 2014;5:8161-72 pubmed
Kawauchi S, Nakamura T, Yasui H, Nishikawa C, Miki I, Inoue J, et al. Intestinal and hepatic expression of cytochrome P450s and mdr1a in rats with indomethacin-induced small intestinal ulcers. Int J Med Sci. 2014;11:1208-17 pubmed publisher
Aoyama A, Katayama R, Oh hara T, Sato S, Okuno Y, Fujita N. Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter-mediated drug resistance. Mol Cancer Ther. 2014;13:2978-90 pubmed publisher
Lee M, Marina M, King J, Saavedra H. Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells. Cell Div. 2014;9:3 pubmed publisher
Tan P, Du S, Ren C, Yao Q, Zheng R, Li R, et al. MicroRNA-207 enhances radiation-induced apoptosis by directly targeting Akt3 in cochlea hair cells. Cell Death Dis. 2014;5:e1433 pubmed publisher
Hosoya T, Sakai F, Yamashita M, Shiozaki T, Endo T, Ukibe K, et al. Lactobacillus helveticus SBT2171 inhibits lymphocyte proliferation by regulation of the JNK signaling pathway. PLoS ONE. 2014;9:e108360 pubmed publisher
Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, et al. IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci. 2014;34:12982-99 pubmed publisher
Hirahashi J, Kawahata K, Arita M, Iwamoto R, Hishikawa K, Honda M, et al. Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis. Sci Rep. 2014;4:6406 pubmed publisher
Ali J, Lagasse B, Minuk A, Love A, Moraya A, Lam L, et al. Differential cellular responses induced by dorsomorphin and LDN-193189 in chemotherapy-sensitive and chemotherapy-resistant human epithelial ovarian cancer cells. Int J Cancer. 2015;136:E455-69 pubmed publisher
Romberg N, Al Moussawi K, Nelson Williams C, Stiegler A, Loring E, Choi M, et al. Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation. Nat Genet. 2014;46:1135-1139 pubmed publisher
Fu X, Creighton C, Biswal N, Kumar V, Shea M, Herrera S, et al. Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Breast Cancer Res. 2014;16:430 pubmed publisher
Engel N, Falodun A, Kühn J, Kragl U, Langer P, Nebe B. Pro-apoptotic and anti-adhesive effects of four African plant extracts on the breast cancer cell line MCF-7. BMC Complement Altern Med. 2014;14:334 pubmed publisher
Crestani C, Lopes da Silva A, Scopinho A, Ruginsk S, Uchoa E, Correa F, et al. Cardiovascular alterations at different stages of hypertension development during ethanol consumption: time-course of vascular and autonomic changes. Toxicol Appl Pharmacol. 2014;280:245-55 pubmed publisher
Xu J, Wang T, Cao Z, Huang H, Li J, Liu W, et al. MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis. Oncotarget. 2014;5:6983-93 pubmed
Gao Y, Trivedi S, Ferris R, Koide K. Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells. Sci Rep. 2014;4:6098 pubmed publisher
Jang W, Jung S, Kang J, Jeong J, Bae M, Joo S, et al. Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification. Cancer Sci. 2014;105:1245-53 pubmed publisher
Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, et al. ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway. Nucleic Acids Res. 2014;42:10037-49 pubmed publisher
Imura Y, Yasui H, Outani H, Wakamatsu T, Hamada K, Nakai T, et al. Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma. Mol Cancer. 2014;13:185 pubmed publisher
Saito M, Ishigame T, Tsuta K, Kumamoto K, Imai T, Kohno T. A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis. Carcinogenesis. 2014;35:2452-6 pubmed publisher
Haobam B, Nozawa T, Minowa Nozawa A, Tanaka M, Oda S, Watanabe T, et al. Rab17-mediated recycling endosomes contribute to autophagosome formation in response to Group A Streptococcus invasion. Cell Microbiol. 2014;16:1806-21 pubmed publisher
Ali B, Al Salam S, Al Za abi M, Al Balushi K, Ramkumar A, Waly M, et al. Does swimming exercise affect experimental chronic kidney disease in rats treated with gum acacia?. PLoS ONE. 2014;9:e102528 pubmed publisher
Ohtsubo K, Yamada T, Zhao L, Jin T, Takeuchi S, Mouri H, et al. Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer. Pancreas. 2014;43:1093-100 pubmed publisher
Liang Y, Chen M, Hua Y, Chen S, Zheng L, Cao X, et al. Downregulation of Ras association domain family member 6 (RASSF6) underlies the treatment resistance of highly metastatic nasopharyngeal carcinoma cells. PLoS ONE. 2014;9:e100843 pubmed publisher
Gao X, Zhang H, Zhuang W, Yuan G, Sun T, Jiang X, et al. PEDF and PEDF-derived peptide 44mer protect cardiomyocytes against hypoxia-induced apoptosis and necroptosis via anti-oxidative effect. Sci Rep. 2014;4:5637 pubmed publisher
Chen J, Li L, Su J, Li B, Chen T, Wong Y. Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. PLoS ONE. 2014;9:e101277 pubmed publisher
Shen Y, Luo Q, Guo Y, Zheng G, Yu J, Xu Y. Bone marrow mesenchymal stem cell-derived Wnt5a inhibits leukemia cell progression in vitro via activation of the non-canonical Wnt signaling pathway. Oncol Lett. 2014;8:85-90 pubmed
Dimitrijević A, Qin Z, Aswad D. Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse. PLoS ONE. 2014;9:e100622 pubmed publisher
Tanimoto A, Yamada T, Nanjo S, Takeuchi S, Ebi H, Kita K, et al. Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells. Oncotarget. 2014;5:4920-8 pubmed
Huang L, Zhu G, Deng Y, Jiang W, Fang M, Chen C, et al. Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-? and IL-1?-induced Na-K-Cl Cotransporter up-regulation. J Neuroinflammation. 2014;11:102 pubmed publisher
Cholewa B, Pellitteri Hahn M, Scarlett C, Ahmad N. Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells. J Proteome Res. 2014;13:5041-50 pubmed publisher
O Neill S, Hinkle C, Chen S, Sandhu A, Hovhannisyan R, Stephan S, et al. Targeting adipose tissue via systemic gene therapy. Gene Ther. 2014;21:653-61 pubmed publisher
Sahasrabuddhe N, Huang T, Ahmad S, Kim M, Yang Y, Ghosh B, et al. Regulation of PPAR-alpha pathway by Dicer revealed through proteomic analysis. J Proteomics. 2014;108:306-15 pubmed publisher
Zhang Q, Ding Y, Lei Y, Qi C, He X, Lan T, et al. Andrographolide suppress tumor growth by inhibiting TLR4/NF-?B signaling activation in insulinoma. Int J Biol Sci. 2014;10:404-14 pubmed publisher
Ankrum J, Dastidar R, Ong J, Levy O, Karp J. Performance-enhanced mesenchymal stem cells via intracellular delivery of steroids. Sci Rep. 2014;4:4645 pubmed publisher
Sweigard J, Yanai R, Gaissert P, Saint Geniez M, Kataoka K, Thanos A, et al. The alternative complement pathway regulates pathological angiogenesis in the retina. FASEB J. 2014;28:3171-82 pubmed publisher
Xu J, Wang T, You L, Zheng L, Shu H, Zhang T, et al. Insulin-like growth factor 1 receptor (IGF-1R) as a target of MiR-497 and plasma IGF-1R levels associated with TNM stage of pancreatic cancer. PLoS ONE. 2014;9:e92847 pubmed publisher
Huang P, Watanabe M, Kaku H, Ueki H, Noguchi H, Sugimoto M, et al. Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line. Mol Clin Oncol. 2013;1:180-184 pubmed
Gao J, Xiao S, Liu X, Wang L, Ji Q, Mo D, et al. Inhibition of HSP70 reduces porcine reproductive and respiratory syndrome virus replication in vitro. BMC Microbiol. 2014;14:64 pubmed publisher
Liu M, Song S, Li H, Jiang X, Yin P, Wan C, et al. The protective effect of caffeic acid against inflammation injury of primary bovine mammary epithelial cells induced by lipopolysaccharide. J Dairy Sci. 2014;97:2856-65 pubmed publisher
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher
Wattenberg M, Kwilas A, Gameiro S, Dicker A, Hodge J. Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br J Cancer. 2014;110:1472-80 pubmed publisher
Kazi A, Gilani R, Schech A, Chumsri S, Sabnis G, Shah P, et al. Nonhypoxic regulation and role of hypoxia-inducible factor 1 in aromatase inhibitor resistant breast cancer. Breast Cancer Res. 2014;16:R15 pubmed publisher
Volgin D, Lu J, Stettner G, Mann G, Ross R, Morrison A, et al. Time- and behavioral state-dependent changes in posterior hypothalamic GABAA receptors contribute to the regulation of sleep. PLoS ONE. 2014;9:e86545 pubmed publisher
Laget S, Miotto B, Chin H, Esteve P, Roberts R, Pradhan S, et al. MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress. Epigenetics. 2014;9:546-56 pubmed publisher
Chen X, Mak I. Mg supplementation protects against ritonavir-mediated endothelial oxidative stress and hepatic eNOS downregulation. Free Radic Biol Med. 2014;69:77-85 pubmed publisher
Battiston K, Ouyang B, Labow R, Simmons C, Santerre J. Monocyte/macrophage cytokine activity regulates vascular smooth muscle cell function within a degradable polyurethane scaffold. Acta Biomater. 2014;10:1146-55 pubmed publisher
Itokazu T, Hayano Y, Takahashi R, Yamashita T. Involvement of Wnt/?-catenin signaling in the development of neuropathic pain. Neurosci Res. 2014;79:34-40 pubmed publisher
Gong Z, Kennedy O, Sun H, Wu Y, Williams G, Klein L, et al. Reductions in serum IGF-1 during aging impair health span. Aging Cell. 2014;13:408-18 pubmed publisher
Wang L, Cheng X, Li H, Qiu F, Yang N, Wang B, et al. Quercetin reduces oxidative stress and inhibits activation of c?Jun N?terminal kinase/activator protein?1 signaling in an experimental mouse model of abdominal aortic aneurysm. Mol Med Rep. 2014;9:435-42 pubmed publisher
Yang Y, Inatsuka C, Gad E, Disis M, Standish L, Pugh N, et al. Protein-bound polysaccharide-K induces IL-1? via TLR2 and NLRP3 inflammasome activation. Innate Immun. 2014;20:857-66 pubmed publisher
Al Dossary A, Strehler E, Martin DeLeon P. Expression and secretion of plasma membrane Ca2+-ATPase 4a (PMCA4a) during murine estrus: association with oviductal exosomes and uptake in sperm. PLoS ONE. 2013;8:e80181 pubmed publisher
Zhang G, Wang Z, Luo W, Jiao H, Wu J, Jiang C. Expression of Potential Cancer Stem Cell Marker ABCG2 is Associated with Malignant Behaviors of Hepatocellular Carcinoma. Gastroenterol Res Pract. 2013;2013:782581 pubmed publisher
Kumar D, Shankar S, Srivastava R. Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway. Cancer Lett. 2014;343:179-89 pubmed publisher
Roca H, Hernandez J, Weidner S, McEachin R, Fuller D, Sud S, et al. Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer. PLoS ONE. 2013;8:e76773 pubmed publisher
Raida Z, Hundahl C, Nyengaard J, Hay Schmidt A. Neuroglobin over expressing mice: expression pattern and effect on brain ischemic infarct size. PLoS ONE. 2013;8:e76565 pubmed publisher
Guo X, Dong Y, Yin S, Zhao C, Huo Y, Fan L, et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis. 2013;4:e822 pubmed publisher
Adolph T, Tomczak M, Niederreiter L, Ko H, Böck J, Martínez Naves E, et al. Paneth cells as a site of origin for intestinal inflammation. Nature. 2013;503:272-6 pubmed publisher
Tagliati F, Gagliano T, Gentilin E, Minoia M, Molè D, Delgi Uberti E, et al. Magmas overexpression inhibits staurosporine induced apoptosis in rat pituitary adenoma cell lines. PLoS ONE. 2013;8:e75194 pubmed publisher
Chen M, Li W, Lue Y, Chu C, Pan I, Ko C, et al. Clitocybe nuda Activates Dendritic Cells and Acts as a DNA Vaccine Adjuvant. Evid Based Complement Alternat Med. 2013;2013:761454 pubmed publisher
Cao L, Cao Y, Xu C, Edvinsson L. Altered endothelin receptor expression and affinity in spontaneously hypertensive rat cerebral and coronary arteries. PLoS ONE. 2013;8:e73761 pubmed publisher
Trefry J, Wooley D. Silver nanoparticles inhibit vaccinia virus infection by preventing viral entry through a macropinocytosis-dependent mechanism. J Biomed Nanotechnol. 2013;9:1624-35 pubmed
Sun N, Hao J, Li X, Yin X, Zong Y, Zhang G, et al. GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats. Cell Death Dis. 2013;4:e771 pubmed publisher
Deng Y, Ma H, Tsuneyama K, Yang W, Wang Y, Lu F, et al. STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib. J Autoimmun. 2013;46:25-34 pubmed publisher
Chowdhury S, Guha R, Trivedi R, Kompella U, Konar A, Hazra S. Pirfenidone nanoparticles improve corneal wound healing and prevent scarring following alkali burn. PLoS ONE. 2013;8:e70528 pubmed publisher
Hong Y, Wu J, Zhao J, Wang H, Liu Y, Chen T, et al. miR-29b and miR-29c are involved in Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid dendritic cells. PLoS ONE. 2013;8:e69926 pubmed publisher
Asano R, Hagiwara Y, Koyama N, Masakari Y, Orimo R, Arai K, et al. Multimerization of anti-(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers. FEBS J. 2013;280:4816-26 pubmed publisher
Hagen K, Zeng X, Lee M, Tucker Kahn S, Harrison Pitner M, Zaky S, et al. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis. Cell Div. 2013;8:10 pubmed publisher
Sitnick M, Basantani M, Cai L, Schoiswohl G, Yazbeck C, Distefano G, et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013;62:3350-61 pubmed publisher
Kluk M, Ashworth T, Wang H, Knoechel B, Mason E, Morgan E, et al. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS ONE. 2013;8:e67306 pubmed publisher
Yuan Y, Tang A, Castoreno A, Kuo S, Wang Q, Kuballa P, et al. Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. Cell Death Dis. 2013;4:e690 pubmed publisher
Wang Q, Wang Y, Zhang Y, Zhang Y, Xiao W. The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease. Respir Res. 2013;14:67 pubmed publisher
Yin X, Yan J, Hou X, Wu S, Zhang G. Neuroprotection of S-nitrosoglutathione against ischemic injury by down-regulating Fas S-nitrosylation and downstream signaling. Neuroscience. 2013;248:290-8 pubmed publisher
Umeshappa C, Xie Y, Xu S, Nanjundappa R, Freywald A, Deng Y, et al. Th cells promote CTL survival and memory via acquired pMHC-I and endogenous IL-2 and CD40L signaling and by modulating apoptosis-controlling pathways. PLoS ONE. 2013;8:e64787 pubmed publisher
Harrison Pitner M, Saavedra H. Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model. PLoS ONE. 2013;8:e65971 pubmed publisher
Gilda J, Gomes A. Stain-Free total protein staining is a superior loading control to ?-actin for Western blots. Anal Biochem. 2013;440:186-8 pubmed publisher
Jiang L, Luo M, Liu D, Chen B, Zhang W, Mai L, et al. BAD overexpression inhibits cell growth and induces apoptosis via mitochondrial-dependent pathway in non-small cell lung cancer. Cancer Cell Int. 2013;13:53 pubmed publisher
Burgers T, Hoffmann M, Collins C, Zahatnansky J, Alvarado M, Morris M, et al. Mice lacking pten in osteoblasts have improved intramembranous and late endochondral fracture healing. PLoS ONE. 2013;8:e63857 pubmed publisher
Jamieson S, Fuller P. Characterization of the inhibitor of kappaB kinase (IKK) complex in granulosa cell tumors of the ovary and granulosa cell tumor-derived cell lines. Horm Cancer. 2013;4:277-92 pubmed publisher
Jung Y, Kim J, Shiozawa Y, Wang J, Mishra A, Joseph J, et al. Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis. Nat Commun. 2013;4:1795 pubmed publisher
Mitrpant C, Porensky P, Zhou H, Price L, Muntoni F, Fletcher S, et al. Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophy. PLoS ONE. 2013;8:e62114 pubmed publisher
Sakabe J, Yamamoto M, Hirakawa S, Motoyama A, Ohta I, Tatsuno K, et al. Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes. J Biol Chem. 2013;288:17179-89 pubmed publisher
Peng Z, Liu M, Fang Z, Chen L, Wu J, Zhang Q. In vitro antiproliferative effect of a water-soluble Laminaria japonica polysaccharide on human melanoma cell line A375. Food Chem Toxicol. 2013;58:56-60 pubmed publisher
Katayama R, Aoyama A, Yamori T, Qi J, Oh hara T, Song Y, et al. Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition. Cancer Res. 2013;73:3087-96 pubmed publisher
Kase E, Nikolić N, Bakke S, Bogen K, Aas V, Thoresen G, et al. Remodeling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells. PLoS ONE. 2013;8:e59972 pubmed publisher
Tanaka T, Fujita Y, Ueno M, Shultz L, Yamashita T. Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury. Cell Death Dis. 2013;4:e567 pubmed publisher
McKinley E, Ayers G, Smith R, Saleh S, Zhao P, Washington M, et al. Limits of [18F]-FLT PET as a biomarker of proliferation in oncology. PLoS ONE. 2013;8:e58938 pubmed publisher
Kim B, Zaveri H, Shchelochkov O, Yu Z, Hernandez Garcia A, Seymour M, et al. An allelic series of mice reveals a role for RERE in the development of multiple organs affected in chromosome 1p36 deletions. PLoS ONE. 2013;8:e57460 pubmed publisher
Chen L, Stuart L, Ohsumi T, Burgess S, Varshney G, Dastur A, et al. Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics. BMC Cancer. 2013;13:93 pubmed publisher
Zhang Q, Chen Q, Lu X, Zhou Z, Zhang H, Lin H, et al. CUL1 promotes trophoblast cell invasion at the maternal-fetal interface. Cell Death Dis. 2013;4:e502 pubmed publisher
Hagenlocher Y, Bergheim I, Zacheja S, Schaffer M, Bischoff S, Lorentz A. Cinnamon extract inhibits degranulation and de novo synthesis of inflammatory mediators in mast cells. Allergy. 2013;68:490-7 pubmed publisher
Li Y, Meeran S, Patel S, Chen H, Hardy T, Tollefsbol T. Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. Mol Cancer. 2013;12:9 pubmed publisher
Uto Konomi A, McKibben B, Wirtz J, Sato Y, Takano A, Nanki T, et al. CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4. Biochem Biophys Res Commun. 2013;431:772-6 pubmed publisher
Schiffhauer E, Vij N, Kovbasnjuk O, Kang P, Walker D, Lee S, et al. Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia. Am J Physiol Lung Cell Mol Physiol. 2013;304:L324-31 pubmed publisher
Chou N, Cheng C, Wu H, Lai C, Lin L, Pan I, et al. Chlorella sorokiniana-Induced Activation and Maturation of Human Monocyte-Derived Dendritic Cells through NF-?B and PI3K/MAPK Pathways. Evid Based Complement Alternat Med. 2012;2012:735396 pubmed publisher
Killen M, Stults D, Wilson W, Pierce A. Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes. BMC Mol Biol. 2012;13:33 pubmed publisher
Bhargava P, Li C, Stanya K, Jacobi D, Dai L, Liu S, et al. Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways. Nat Med. 2012;18:1665-72 pubmed publisher
Han D, Zhang M, Ma J, Hong J, Chen C, Zhang B, et al. Transition pattern and mechanism of B-lymphocyte precursors in regenerated mouse bone marrow after subtotal body irradiation. PLoS ONE. 2012;7:e46560 pubmed publisher
Sydor S, Gu Y, Schlattjan M, Bechmann L, Rauen U, Best J, et al. Steatosis does not impair liver regeneration after partial hepatectomy. Lab Invest. 2013;93:20-30 pubmed publisher
Yamada T, Takeuchi S, Fujita N, Nakamura A, Wang W, Li Q, et al. Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations. Oncogene. 2013;32:4427-35 pubmed publisher
Li Y, Zhang Y, Li R, Chen W, Howell M, Zhang R, et al. The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells. PLoS ONE. 2012;7:e45210 pubmed publisher
Cao L, Zhang Y, Cao Y, Edvinsson L, Xu C. Secondhand smoke exposure causes bronchial hyperreactivity via transcriptionally upregulated endothelin and 5-hydroxytryptamine 2A receptors. PLoS ONE. 2012;7:e44170 pubmed publisher
Rodríguez Martín S, Kropp K, Wilhelmi V, Lisnic V, Hsieh W, Blanc M, et al. Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection. PLoS Pathog. 2012;8:e1002901 pubmed publisher
Meinen S, Lin S, Ruegg M. Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-?2-deficient congenital muscular dystrophy (MDC1A). Skelet Muscle. 2012;2:18 pubmed publisher
Liao W, Zhao R, Lu L, Zhang R, Zou J, Xu T, et al. Overexpression of a novel osteopetrosis-related gene CCDC154 suppresses cell proliferation by inducing G2/M arrest. Cell Cycle. 2012;11:3270-9 pubmed publisher
Ou Y, Ma L, Dong L, Ma L, Zhao Z, Ma L, et al. Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-? and STAT3 protein signaling pathways. J Biol Chem. 2012;287:32394-405 pubmed
Diermeier Daucher S, Ortmann O, Buchholz S, Brockhoff G. Trifunctional antibody ertumaxomab: Non-immunological effects on Her2 receptor activity and downstream signaling. MAbs. 2012;4:614-22 pubmed publisher
Yanaihara N, Anglesio M, Ochiai K, Hirata Y, Saito M, Nagata C, et al. Cytokine gene expression signature in ovarian clear cell carcinoma. Int J Oncol. 2012;41:1094-100 pubmed publisher
Riedel A, Pignitter M, Hochkogler C, Rohm B, Walker J, Bytof G, et al. Caffeine dose-dependently induces thermogenesis but restores ATP in HepG2 cells in culture. Food Funct. 2012;3:955-64 pubmed publisher
Garcia I, Crowther A, Gama V, Miller C, Miller C, Deshmukh M, et al. Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation. Oncogene. 2013;32:2304-14 pubmed publisher
Ye Y, Gao J, Tian H, Yearsley K, Lange A, Robertson F, et al. Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7. Mol Cancer Res. 2012;10:713-26 pubmed publisher
Koizumi H, Yamada T, Takeuchi S, Nakagawa T, Kita K, Nakamura T, et al. Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR-mutant lung cancer by decreasing client protein expression and angiogenesis. J Thorac Oncol. 2012;7:1078-85 pubmed publisher
Ye Y, Xiao Y, Wang W, Gao J, Yearsley K, Yan Q, et al. Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis. Oncotarget. 2012;3:475-89 pubmed
Schachtele S, Hu S, Lokensgard J. Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment. PLoS ONE. 2012;7:e36216 pubmed publisher
Yamada T, Takeuchi S, Nakade J, Kita K, Nakagawa T, Nanjo S, et al. Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells. Clin Cancer Res. 2012;18:3592-602 pubmed publisher
Zhang Y, Li X, Huang Z, Zheng W, Fan C, Chen T. Enhancement of cell permeabilization apoptosis-inducing activity of selenium nanoparticles by ATP surface decoration. Nanomedicine. 2013;9:74-84 pubmed publisher
Gong L, Yu H, Zhuge Y, Yu Q. Neutrophil gelatinase-associated lipocalin protects renal tubular epithelial cell in ischemic/reperfusion injury rats via apoptosis-regulating proteins. Ren Fail. 2012;34:777-83 pubmed publisher
Ma R, Liu J, Wu L, Sun J, Yang Z, Yu C, et al. Differential expression of placental 11?-hydroxysteroid dehydrogenases in pregnant women with diet-treated gestational diabetes mellitus. Steroids. 2012;77:798-805 pubmed publisher
D Agostino J, Ding X, Zhang P, Jia K, Fang C, Zhu Y, et al. Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes. J Biol Chem. 2012;287:17777-88 pubmed publisher
Yang G, Yao Y, Zhou J, Zhao Q. Effects of icotinib, a novel epidermal growth factor receptor tyrosine kinase inhibitor, in EGFR-mutated non-small cell lung cancer. Oncol Rep. 2012;27:2066-72 pubmed publisher
Cao L, Zhang Y, Cao Y, Edvinsson L, Xu C. Cigarette smoke upregulates rat coronary artery endothelin receptors in vivo. PLoS ONE. 2012;7:e33008 pubmed publisher
Hulsmans M, Van Dooren E, Mathieu C, Holvoet P. Decrease of miR-146b-5p in monocytes during obesity is associated with loss of the anti-inflammatory but not insulin signaling action of adiponectin. PLoS ONE. 2012;7:e32794 pubmed publisher
Ifeadi V, Garnett Benson C. Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways. PLoS ONE. 2012;7:e31762 pubmed publisher
Bais M, Nugent M, Stephens D, Sume S, Kirsch K, Sonenshein G, et al. Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts. PLoS ONE. 2012;7:e31188 pubmed publisher
Märker T, Sell H, Zillessen P, Glöde A, Kriebel J, Ouwens D, et al. Heat shock protein 60 as a mediator of adipose tissue inflammation and insulin resistance. Diabetes. 2012;61:615-25 pubmed publisher
Lee K, Kalantzis A, Jackson C, O Connor L, Murata Kamiya N, Hatakeyama M, et al. Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3? via gastric STAT3 activation. PLoS ONE. 2012;7:e30786 pubmed publisher
Janas M, Khaled M, Schubert S, Bernstein J, Golan D, Veguilla R, et al. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. PLoS Genet. 2011;7:e1002330 pubmed publisher
Vader P, Crielaard B, van Dommelen S, van der Meel R, Storm G, Schiffelers R. Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles. J Control Release. 2012;160:211-6 pubmed publisher
Tsai Y, Pestka S, Wang L, Runnels L, Wan S, Lyu Y, et al. Interferon-? signaling contributes to Ras transformation. PLoS ONE. 2011;6:e24291 pubmed publisher
Ippagunta S, Malireddi R, Shaw P, Neale G, Vande Walle L, Green D, et al. The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization. Nat Immunol. 2011;12:1010-6 pubmed publisher
Sadighi Akha A, Harper J, Salmon A, Schroeder B, Tyra H, Rutkowski D, et al. Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity. J Biol Chem. 2011;286:30344-51 pubmed publisher
Fancy S, Harrington E, Yuen T, Silbereis J, Zhao C, Baranzini S, et al. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011;14:1009-16 pubmed publisher
Wang O, Liu S, Zou J, Lu L, Chen L, Qiu S, et al. Anticancer activity of 2?, 3?, 19?, 23?-Tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid isolated from Sinojackia sarcocarpa. PLoS ONE. 2011;6:e21130 pubmed publisher
Zheng Y, Zhang H, Zhang X, Feng D, Luo X, Zeng C, et al. MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene. 2012;31:80-92 pubmed publisher
Ikner A, Ashkenazi A. TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. J Biol Chem. 2011;286:21546-54 pubmed publisher
Blanc M, Hsieh W, Robertson K, Watterson S, Shui G, Lacaze P, et al. Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS Biol. 2011;9:e1000598 pubmed publisher
Zhao Q, Wang C, Zhu J, Wang L, Dong S, Zhang G, et al. RNAi-mediated knockdown of cyclooxygenase2 inhibits the growth, invasion and migration of SaOS2 human osteosarcoma cells: a case control study. J Exp Clin Cancer Res. 2011;30:26 pubmed publisher
Berg V, Sveinbjörnsson B, Bendiksen S, Brox J, Meknas K, Figenschau Y. Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157). Arthritis Res Ther. 2010;12:R228 pubmed publisher
Adon A, Zeng X, Harrison M, Sannem S, Kiyokawa H, Kaldis P, et al. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells. Mol Cell Biol. 2010;30:694-710 pubmed publisher
Zhang S, Tang Q, Xu F, Xue Y, Zhen Z, Deng Y, et al. RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors. Mol Cancer Res. 2009;7:570-80 pubmed publisher
Peng T, Chen J, Mao W, Song X, Chen M. Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9. BMC Cell Biol. 2009;10:27 pubmed publisher
Zhang H, Liu C, Zha Z, Zhao B, Yao J, Zhao S, et al. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem. 2009;284:13355-62 pubmed publisher
Wei S, Yu Y, Zhang Z, Felder R. Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. Am J Physiol Heart Circ Physiol. 2009;296:H1425-33 pubmed publisher
product information
SKU :
4970L
Product-Name :
β-Actin (13E5) Rabbit mAb
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M, R, Mk, B, Pg, (Hm, C, Dg, Hr)
Applications :
Flow cytometry
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
45
Host :
Rabbit
Target :
beta-Actin
Primary-Protein :
ACTB
Alt-Names :
ACTB,Actin, cytoplasmic 1,Actin, cytoplasmic 1, N-terminally processed,Beta-actin,PS1TP5-binding protein 1,PS1TP5BP1,actin, beta,beta actin,beta cytoskeletal actin
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.