product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Actin Antibody
catalog :
4967
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow, zebrafish , fruit fly, rabbit
application :
western blot, immunohistochemistry, immunoprecipitation, other, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 321
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig s2
Oda S, Nozawa T, Nozawa Minowa A, Tanaka M, Aikawa C, Harada H, et al. Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes. PLoS ONE. 2016;11:e0147061 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Roncal Jimenez C, Milagres T, Andres Hernando A, Kuwabara M, Jensen T, Song Z, et al. Effects of exogenous desmopressin on a model of heat stress nephropathy in mice. Am J Physiol Renal Physiol. 2017;312:F418-F426 pubmed publisher
  • western blot; human; 1:1000; fig 3
Silva S, Levy D, Ruiz J, de Melo T, Isaac C, Fidelis M, et al. Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death. J Steroid Biochem Mol Biol. 2017;169:164-175 pubmed publisher
  • western blot; mouse; 1:2000; fig 4
Cheng Y, Cawley N, Yanik T, Murthy S, Liu C, Kasikci F, et al. A human carboxypeptidase E/NF-?1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice. Transl Psychiatry. 2016;6:e973 pubmed publisher
  • western blot; human; 1:1000; fig 4
Tseng H, Vong C, Kwan Y, Lee S, Hoi M. TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Sci Rep. 2016;6:35016 pubmed publisher
  • western blot; human; 1:2000; fig 1
Grolmusz V, Karaszi K, Micsik T, Toth E, Mészáros K, Karvaly G, et al. Cell cycle dependent RRM2 may serve as proliferation marker and pharmaceutical target in adrenocortical cancer. Am J Cancer Res. 2016;6:2041-2053 pubmed
  • western blot; human; fig 2
Zhang Y, Zhang Y, Zhong C, Xiao F. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci Rep. 2016;6:34578 pubmed publisher
  • western blot; human; 1:2000; fig 1
Yao J, Qin L, Miao S, Wang X, Wu X. Overexpression of miR-506 suppresses proliferation and promotes apoptosis of osteosarcoma cells by targeting astrocyte elevated gene-1. Oncol Lett. 2016;12:1840-1848 pubmed
  • western blot; human; 1:1000; fig 1
Timucin A, Basaga H. SIRT6 Is a Positive Regulator of Aldose Reductase Expression in U937 and HeLa cells under Osmotic Stress: In Vitro and In Silico Insights. PLoS ONE. 2016;11:e0161494 pubmed publisher
  • western blot; human; 1:1000; fig 5
Durand S, Franks T, Lykke Andersen J. Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay. Nat Commun. 2016;7:12434 pubmed publisher
  • western blot; human; fig 5
Martinez L, Thames E, Kim J, Chaudhuri G, Singh R, Pervin S. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer. 2016;16:559 pubmed publisher
  • western blot; human; fig 5
Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed publisher
  • western blot; human; 1:2000; fig s2
Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERR? mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
  • western blot; mouse; 1:5000; fig 7D
Liu S, Li Q, Zhang M, Mao Ying Q, Hu L, Wu G, et al. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Sci Rep. 2016;6:28956 pubmed publisher
  • western blot; mouse; fig 5c
Shen J, Li Z, Li L, Lu L, Xiao Z, Wu W, et al. Vascular-targeted TNF? and IFN? inhibits orthotopic colorectal tumor growth. J Transl Med. 2016;14:187 pubmed publisher
  • western blot; mouse; fig 4
Roychowdhury S, McCullough R, Sanz Garcia C, Saikia P, Alkhouri N, Matloob A, et al. Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. Hepatology. 2016;64:1518-1533 pubmed publisher
  • western blot; fruit fly; 1:2000; fig 2c
Tran M, Tsarouhas V, Kegel A. Early development of Drosophila embryos requires Smc5/6 function during oogenesis. Biol Open. 2016;5:928-41 pubmed publisher
  • western blot; rat; 1:4000; fig 1
Chunchai T, Samniang B, Sripetchwandee J, Pintana H, Pongkan W, Kumfu S, et al. Vagus Nerve Stimulation Exerts the Neuroprotective Effects in Obese-Insulin Resistant Rats, Leading to the Improvement of Cognitive Function. Sci Rep. 2016;6:26866 pubmed publisher
  • western blot; human; 1:10,000; loading ...; fig 3b
Zuckerwise L, Li J, Lu L, Men Y, Geng T, Buhimschi C, et al. H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction. Oncotarget. 2016;7:38398-38407 pubmed publisher
  • western blot; mouse; 1:2000; fig 1
Pharaoh G, Pulliam D, Hill S, Sataranatarajan K, Van Remmen H. Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts. Redox Biol. 2016;8:430-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Najibi M, Labed S, Visvikis O, IRAZOQUI J. An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense. Cell Rep. 2016;15:1728-42 pubmed publisher
  • western blot; rat; 1:1000; fig 7
Tokhtaeva E, Sun H, Deiss Yehiely N, Wen Y, Soni P, Gabrielli N, et al. The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase ?1 subunits. J Cell Sci. 2016;129:2394-406 pubmed publisher
  • western blot; rat; fig 1
Jang S, Royston S, Lee G, Wang S, Chung H. Seizure-Induced Regulations of Amyloid-?, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity. Neural Plast. 2016;2016:2123748 pubmed publisher
  • western blot; human; 1:2000; fig 2
McDonnell F, Irnaten M, Clark A, O Brien C, Wallace D. Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGF?1 Expression in Human Trabecular Meshwork Cells. PLoS ONE. 2016;11:e0153354 pubmed publisher
  • western blot; mouse; fig 1a
Anghelina D, Lam E, Falck Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
  • western blot; rat; fig 1
Fortes M, Marzuca Nassr G, Vitzel K, da Justa Pinheiro C, Newsholme P, Curi R. Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?. Anal Biochem. 2016;504:38-40 pubmed publisher
  • western blot; human; fig 1
Panchanathan R, Liu H, Choubey D. Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation. Oncotarget. 2016;7:28183-94 pubmed publisher
  • western blot; mouse; 1:2000; fig 2
  • western blot; human; 1:2000; fig 1
Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher
  • western blot; rat; 1:1000; fig 5
Xu W, Huang M, Zhang Y, Li H, Zheng H, Yu L, et al. Extracts of Bauhinia championii (Benth.) Benth. attenuate the in?ammatory response in a rat model of collagen-induced arthritis. Mol Med Rep. 2016;13:4167-74 pubmed publisher
  • western blot; mouse; fig 5
Sim C, Cho Y, Kim B, Baek I, Kim Y, Lee M. 2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons. Cancer Immunol Immunother. 2016;65:663-75 pubmed publisher
  • western blot; mouse; fig 4
Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  • western blot; human; 1:2000; fig 1c
Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
  • western blot; human; loading ...; fig 1e
Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Boulter N, Suarez F, Schibeci S, Sunderland T, Tolhurst O, Hunter T, et al. A simple, accurate and universal method for quantification of PCR. BMC Biotechnol. 2016;16:27 pubmed publisher
  • western blot; mouse; fig 4a
Ishibashi K, Nehashi K, Oshima T, Ohkura N, Atsumi G. Differentiation with elaidate tends to impair insulin-dependent glucose uptake and GLUT4 translocation in 3T3-L1 adipocytes. Int J Food Sci Nutr. 2016;67:99-110 pubmed publisher
  • western blot; human; fig 8
Kuosmanen S, Viitala S, Laitinen T, Peräkylä M, Pölönen P, Kansanen E, et al. The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs. Nucleic Acids Res. 2016;44:1760-75 pubmed publisher
  • western blot; mouse; 1:2000; fig 1
  • western blot; human; 1:4000; fig 1
Zheng F, Yue C, Li G, He B, Cheng W, Wang X, et al. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nat Commun. 2016;7:10180 pubmed publisher
  • western blot; mouse; fig 5b
Chang Y, Yang C, Pan S, Chou Y, Chang F, Lai C, et al. DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys. J Clin Invest. 2016;126:721-31 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 3c
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, et al. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway. Reprod Domest Anim. 2016;51:75-84 pubmed publisher
  • western blot; human; fig 2
Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  • western blot; mouse; fig 1
Kurioka T, Matsunobu T, Satoh Y, Niwa K, Endo S, Fujioka M, et al. ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss. Sci Rep. 2015;5:16839 pubmed publisher
  • western blot; human; fig 2
Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  • western blot; mouse; 1:2000; fig 2
Sharma P, Abbasi C, Lazic S, Teng A, Wang D, Dubois N, et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015;6:8391 pubmed publisher
  • western blot; mouse; fig 2
  • western blot; human; fig 3
Xu Y, Morse L, da Silva R, Wang D, Battaglino R. A short report: PAMM, a novel antioxidant protein, induced by oxidative stress. Redox Biol. 2015;6:446-53 pubmed publisher
  • western blot; mouse; 1:4000; fig 3
Li S, TANG J, Chen J, Zhang P, Wang T, Chen T, et al. Regulation of bone formation by baicalein via the mTORC1 pathway. Drug Des Devel Ther. 2015;9:5169-83 pubmed publisher
  • western blot; rat; fig 1
Zhu X, Wang K, Zhang K, Tan X, Wu Z, Sun S, et al. Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1β-Induced Nitrative/Oxidative Stress. Int J Mol Sci. 2015;16:21775-90 pubmed publisher
  • western blot; mouse; 1:5000; fig 2
Liu S, Mi W, Li Q, Zhang M, Han P, Hu S, et al. Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice. Anesthesiology. 2015;123:1154-69 pubmed publisher
  • western blot; zebrafish ; fig 3
Acosta Alvear D, Cho M, Wild T, Buchholz T, Lerner A, Simakova O, et al. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. elife. 2015;4:e08153 pubmed publisher
  • western blot; zebrafish ; fig 3
Diao J, Wang H, Chang N, Zhou X, Zhu X, Wang J, et al. PEG-PLA nanoparticles facilitate siRNA knockdown in adult zebrafish heart. Dev Biol. 2015;406:196-202 pubmed publisher
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; human; fig 3
Park E, Kim N, Ficarro S, Zhang Y, Lee B, Cho A, et al. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat Struct Mol Biol. 2015;22:703-711 pubmed publisher
  • western blot; mouse; fig 1a
Khan M, Walters L, Li Q, Thomas D, Miller J, Zhang Q, et al. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma. Lab Invest. 2015;95:1278-90 pubmed publisher
  • western blot; human; fig 2
Lee S, Roh Y, Kim S, Lee J, Seol S, Lee H, et al. Activation of EZH2 and SUZ12 Regulated by E2F1 Predicts the Disease Progression and Aggressive Characteristics of Bladder Cancer. Clin Cancer Res. 2015;21:5391-403 pubmed publisher
  • western blot; mouse; fig 5
Zhou W, Shao H, Zhang D, Dong J, Cheng W, Wang L, et al. PTEN signaling is required for the maintenance of spermatogonial stem cells in mouse, by regulating the expressions of PLZF and UTF1. Cell Biosci. 2015;5:42 pubmed publisher
  • western blot; human; 1:1000; fig 3
Bish R, Cuevas Polo N, Cheng Z, Hambardzumyan D, Munschauer M, Landthaler M, et al. Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins. Biomolecules. 2015;5:1441-66 pubmed publisher
  • western blot; human; fig 2
Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS ONE. 2015;10:e0132880 pubmed publisher
  • western blot; human
Nagahara T, Shiraha H, Sawahara H, Uchida D, Takeuchi Y, Iwamuro M, et al. Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells. Oncol Rep. 2015;34:1169-77 pubmed publisher
  • western blot; human; 1:2000; fig 1d
  • western blot; mouse; 1:2000; fig 1b
Zhang S, Hu Y, Huang Y, Xu H, Wu G, Dai H. Heat shock protein 27 promotes cell proliferation through activator protein-1 in lung cancer. Oncol Lett. 2015;9:2572-2576 pubmed
  • western blot; human; loading ...; fig 1Bb, 5
Wang S, Zheng G, Zhao L, Xu F, Qian J. Shp-2 contributes to anti-RSV activity in human pulmonary alveolar epithelial cells by interfering with the IFN-α-induced Jak/Stat1 pathway. J Cell Mol Med. 2015;19:2432-40 pubmed publisher
  • western blot; human; 1:1000; fig 3d
Ding B, Gomi K, Rafii S, Crystal R, Walters M. Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells. J Cell Sci. 2015;128:2983-8 pubmed publisher
  • western blot; human
Kourtidis A, Yanagisawa M, Huveldt D, Copland J, Anastasiadis P. Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer. PLoS ONE. 2015;10:e0129964 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Yoshida Y, Shimizu I, Katsuumi G, Jiao S, Suda M, Hayashi Y, et al. p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload. J Mol Cell Cardiol. 2015;85:183-98 pubmed publisher
  • western blot; zebrafish ; fig 4
Yi T, Arthanari H, Akabayov B, Song H, Papadopoulos E, Qi H, et al. eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nat Commun. 2015;6:7194 pubmed publisher
  • western blot; mouse; fig s3
Yousef H, Conboy M, Morgenthaler A, Schlesinger C, Bugaj L, Paliwal P, et al. Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Oncotarget. 2015;6:11959-78 pubmed
  • western blot; mouse; 1:5000; fig 5
Long L, Anderson P, Frank E, Shaw A, Liu S, Huang X, et al. Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse. PLoS ONE. 2015;10:e0124114 pubmed publisher
  • western blot; rabbit; 1:1000; fig 3
Li P, Zhang L. Exogenous Nkx2.5- or GATA-4-transfected rabbit bone marrow mesenchymal stem cells and myocardial cell co-culture on the treatment of myocardial infarction in rabbits. Mol Med Rep. 2015;12:2607-21 pubmed publisher
  • western blot; mouse
Watanabe M, Ueda T, Shibata Y, Kumamoto N, Shimada S, Ugawa S. Expression and Regulation of Cav3.2 T-Type Calcium Channels during Inflammatory Hyperalgesia in Mouse Dorsal Root Ganglion Neurons. PLoS ONE. 2015;10:e0127572 pubmed publisher
  • western blot; human; fig 6
Yu Y, Koehn C, Yue Y, Li S, Thiele G, Hearth Holmes M, et al. Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation. Curr Mol Med. 2015;15:401-10 pubmed
  • western blot; human; 1:1000; fig 6
Fullár A, Dudás J, Oláh L, Hollósi P, Papp Z, Sobel G, et al. Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression. BMC Cancer. 2015;15:256 pubmed publisher
  • western blot; mouse; 1:1000; fig 2A
Watzlawik J, Kahoud R, Ng S, Painter M, Papke L, Zoecklein L, et al. Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. J Neurochem. 2015;134:865-78 pubmed publisher
  • western blot; mouse; fig 3
Di C, Lin X, Zhang Y, Zhong W, Yuan Y, Zhou T, et al. Basophil-associated OX40 ligand participates in the initiation of Th2 responses during airway inflammation. J Biol Chem. 2015;290:12523-36 pubmed publisher
  • western blot; human
Nagano G, Ohno H, Oki K, Kobuke K, Shiwa T, Yoneda M, et al. Activation of classical brown adipocytes in the adult human perirenal depot is highly correlated with PRDM16-EHMT1 complex expression. PLoS ONE. 2015;10:e0122584 pubmed publisher
  • western blot; human; 1:1000
Sakai M, Martinez Arguelles D, Patterson N, Chaurand P, Papadopoulos V. In search of the molecular mechanisms mediating the inhibitory effect of the GnRH antagonist degarelix on human prostate cell growth. PLoS ONE. 2015;10:e0120670 pubmed publisher
  • western blot; rat; 1:2000; fig 5
McKenna B, Guo M, Reynolds A, Hara M, Stein R. Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells. Cell Rep. 2015;10:2032-42 pubmed publisher
  • western blot; human
Bogaerts E, Heindryckx F, Devisscher L, Paridaens A, Vandewynckel Y, Van den Bussche A, et al. Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors. PLoS ONE. 2015;10:e0119555 pubmed publisher
  • western blot; human
Koob S, Barrera M, Anand R, Reichert A. The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions. Biochim Biophys Acta. 2015;1853:1551-63 pubmed publisher
  • western blot; mouse; 1:1000
Zhang L, Li W, Ni J, Wu J, Liu J, Zhang Z, et al. RC/BTB2 is essential for formation of primary cilia in mammalian cells. Cytoskeleton (Hoboken). 2015;72:171-81 pubmed publisher
  • western blot; rat
Opperman C, Sishi B. Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS. Cell Biol Toxicol. 2015;31:83-94 pubmed publisher
  • western blot; human; 1:5000
Li Y, Zhao Y, Zou Q, Zhang K, Wu Y, Zhou C, et al. Preeclampsia does not alter vascular growth and expression of CD31 and vascular endothelial cadherin in human placentas. J Histochem Cytochem. 2015;63:22-31 pubmed publisher
  • western blot; mouse; 1:200
Dong B, Li D, Li R, Chen S, Liu W, Liu W, et al. A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. PLoS ONE. 2014;9:e114113 pubmed publisher
  • western blot; human; 1:1,000
Singla R, Wang J, Singla D. Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation. Am J Physiol Heart Circ Physiol. 2014;307:H1634-42 pubmed publisher
  • western blot; mouse; fig 5
Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
  • western blot; human; fig 2
Dufour M, Faes S, Dormond Meuwly A, Demartines N, Dormond O. PGE2-induced colon cancer growth is mediated by mTORC1. Biochem Biophys Res Commun. 2014;451:587-91 pubmed publisher
  • western blot; human; 1:1000
Chen F, Zhuang M, Peng J, Wang X, Huang T, Li S, et al. Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-β signaling pathway. Mol Med Rep. 2014;10:1999-2003 pubmed publisher
  • western blot; mouse
Schountz T, Quackenbush S, Rovnak J, Haddock E, Black W, Feldmann H, et al. Differential lymphocyte and antibody responses in deer mice infected with Sin Nombre hantavirus or Andes hantavirus. J Virol. 2014;88:8319-31 pubmed publisher
  • western blot; rat; 1:2000
Wu W, Tian R, Hao S, Xu F, Mao X, Liu B. A pre-injury high ethanol intake in rats promotes brain edema following traumatic brain injury. Br J Neurosurg. 2014;28:739-45 pubmed publisher
  • western blot; human
Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
  • western blot; human
Hemachandra L, Patel H, Chandrasena R, Choi J, Piyankarage S, Wang S, et al. SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites. Cancer Prev Res (Phila). 2014;7:505-15 pubmed publisher
  • western blot; dog
Chen S, Otero Y, Mulligan K, Lundblad T, Williams P, McGuinness O. Liver, but not muscle, has an entrainable metabolic memory. PLoS ONE. 2014;9:e86164 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Gorman J, Liu S, Slopack D, Shariati K, Hasanee A, Olenich S, et al. Angiotensin II evokes angiogenic signals within skeletal muscle through co-ordinated effects on skeletal myocytes and endothelial cells. PLoS ONE. 2014;9:e85537 pubmed publisher
  • western blot; human; 1:1000
Bao W, Qiu H, Yang T, Luo X, Zhang H, Wan X. Upregulation of TrkB promotes epithelial-mesenchymal transition and anoikis resistance in endometrial carcinoma. PLoS ONE. 2013;8:e70616 pubmed publisher
  • western blot; mouse; fig 1b
Vink P, Smout W, Driessen Engels L, de Bruin A, Delsing D, Krajnc Franken M, et al. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation. PLoS ONE. 2013;8:e57348 pubmed publisher
Kale J, Kutuk O, Brito G, Andrews T, Leber B, Letai A, et al. Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO Rep. 2018;19: pubmed publisher
Zhai D, Cui C, Xie L, Cai L, Yu J. Sterol regulatory element-binding protein 1 cooperates with c-Myc to promote epithelial-mesenchymal transition in colorectal cancer. Oncol Lett. 2018;15:5959-5965 pubmed publisher
La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, et al. Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis. J Clin Invest. 2018;128:834-845 pubmed publisher
Wu J, Xiang S, Zhang M, Fang B, Huang H, Kwon O, et al. Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity. J Biol Chem. 2018;293:1976-1993 pubmed publisher
Arima K, Komohara Y, Bu L, Tsukamoto M, Itoyama R, Miyake K, et al. Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1β from activated macrophages leads to poor prognosis in pancreatic cancer. Cancer Sci. 2018;109:462-470 pubmed publisher
Ferreira E, Bonfim Melo A, Cordero E, Mortara R. ERM Proteins Play Distinct Roles in Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2017;8:2230 pubmed publisher
Philip C, Laskov I, Beauchamp M, Marques M, Amin O, Bitharas J, et al. Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors. BMC Cancer. 2017;17:638 pubmed publisher
Kishore A, Liang H, Kanchwala M, Xing C, Ganesh T, Akgul Y, et al. Prostaglandin dehydrogenase is a target for successful induction of cervical ripening. Proc Natl Acad Sci U S A. 2017;114:E6427-E6436 pubmed publisher
Tien T, Zhang J, Muto T, Kim D, Sarthy V, Roy S. High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017;58:2915-2921 pubmed publisher
Putz E, Mayfosh A, Kos K, Barkauskas D, Nakamura K, Town L, et al. NK cell heparanase controls tumor invasion and immune surveillance. J Clin Invest. 2017;127:2777-2788 pubmed publisher
Sinha S, Thomas D, Chan S, Gao Y, Brunen D, Torabi D, et al. Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. Nat Commun. 2017;8:15580 pubmed publisher
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product information
SKU :
4967L
Product-Name :
β-Actin Antibody
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, Mi, Dm, Z, B, (C, X, Dg, Pg, Hr)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
45
Host :
Rabbit
Target :
beta-Actin
Primary-Protein :
ACTB
Alt-Names :
ACTB,Actin, cytoplasmic 1,Actin, cytoplasmic 1, N-terminally processed,Beta-actin,PS1TP5-binding protein 1,PS1TP5BP1,actin, beta,beta actin,beta cytoskeletal actin
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.