product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IRF-4 Antibody
catalog :
4964
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, ChIP-Seq
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 3f
Schanz O, Cornez I, Yajnanarayana S, David F, Peer S, Gruber T, et al. Tumor rejection in Cblb -/- mice depends on IL-9 and Th9 cells. J Immunother Cancer. 2021;9: pubmed publisher
  • ChIP-Seq; human; 1-2 ug / 500 ul chr; loading ...; fig 4c
  • chromatin immunoprecipitation; human; loading ...; fig 4c
Senigl F, Maman Y, Dinesh R, Alinikula J, Seth R, Pecnova L, et al. Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation. Cell Rep. 2019;29:3902-3915.e8 pubmed publisher
  • western blot; human; fig 4d
Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher
  • western blot; human; fig 2a
Zhu Y, Shi C, Bruins L, Wang X, Riggs D, Porter B, et al. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4. Blood Cancer J. 2019;9:19 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 2d
Chuang H, Tsai C, Hsueh C, Tan T. GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease. Sci Adv. 2018;4:eaat5401 pubmed publisher
  • western blot; mouse; loading ...; fig 3f
Wang H, Mo L, Xiao X, An S, Liu X, Ba J, et al. Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model. Sci Rep. 2017;7:43322 pubmed publisher
  • western blot; human; 1:1000; fig 3
Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed publisher
  • western blot; human; fig 4
Conery A, Centore R, Neiss A, Keller P, Joshi S, Spillane K, et al. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. elife. 2016;5: pubmed publisher
product information
SKU :
4964S
Product-Name :
IRF-4 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Chromatin Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
51
Host :
Rabbit
Target :
IRF-4
Primary-Protein :
IRF4
Alt-Names :
IRF-4,IRF4,Interferon regulatory factor 4,LSIRF,Lymphocyte-specific interferon regulatory factor,MUM1,Multiple myeloma oncogene 1,NF-EM5
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.