product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
AID (30F12) Rabbit mAb
catalog :
4949
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
30F12
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 5
Reference
Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed publisher
Mu Y, Zelazowska M, McBride K. Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene. J Exp Med. 2017;214:3543-3552 pubmed publisher
Eid M, Maeda K, Almofty S, Singh S, Shimoda M, Sakaguchi N. GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification. J Immunol. 2014;192:5529-39 pubmed publisher
Liu B, Stoop J, Huizinga T, Toes R. IL-21 enhances the activity of the TLR-MyD88-STAT3 pathway but not the classical TLR-MyD88-NF-?B pathway in human B cells to boost antibody production. J Immunol. 2013;191:4086-94 pubmed publisher
Singh S, Maeda K, Eid M, Almofty S, Ono M, Pham P, et al. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy. Nat Commun. 2013;4:1830 pubmed publisher
product information
SKU :
4949S
Product-Name :
AID (30F12) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
24
Host :
Rabbit
Target :
AID
Primary-Protein :
AID
Alt-Names :
AICDA,AID,ARP2,Activation-induced cytidine deaminase,CDA2,Cytidine aminohydrolase,HIGM2,integrated into Burkitt s lymphoma cell line Ramos
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.