product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-MST1 (Thr183)/MST2 (Thr180)
catalog :
49332
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
E7U1D
reactivity :
human, mouse
application :
western blot
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3h
Yu B, Su J, Shi Q, Liu Q, Ma J, Ru G, et al. KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling. Nat Commun. 2022;13:2192 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s1b, s3a
Xu X, Shen X, Wang J, Feng W, Wang M, Miao X, et al. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021;20:e13465 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4h
Dai M, Yan G, Wang N, Daliah G, Edick A, Poulet S, et al. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy. Nat Commun. 2021;12:3055 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s4b
Shields C, Potlapalli S, Cuya Smith S, Chappell S, Chen D, Martinez D, et al. Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target. Mol Oncol. 2021;: pubmed publisher
  • western blot; human; loading ...; fig 2b
Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3a
Rong X, Han Q, Lin X, Kremerskothen J, Wang E. FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells. Cancer Manag Res. 2019;11:3395-3410 pubmed publisher
Wang K, Ma F, Arai S, Wang Y, Varkaris A, Poluben L, et al. WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth. Cancer Res. 2023;83:1016-1030 pubmed publisher
Wong D, Xiao J, Chew T, Pan M, Lee C, Ang J, et al. BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation. Adv Sci (Weinh). 2022;9:e2202834 pubmed publisher
Rigiracciolo D, Nohata N, Lappano R, Cirillo F, Talia M, Adame García S, et al. Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC). J Exp Clin Cancer Res. 2022;41:193 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.