product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SUMO-1 Antibody
catalog :
4930
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, purple sea urchin
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, other
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 4a
Yue X, Zhang C, Zhao Y, Liu J, Lin A, Tan V, et al. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression. Genes Dev. 2017;31:1641-1654 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5a
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4C
Chakraborty K, Raundhal M, Chen B, Morse C, Tyurina Y, Khare A, et al. The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Nat Commun. 2017;8:13944 pubmed publisher
  • immunocytochemistry; mouse; fig 3c
Maroui M, Callé A, Cohen C, Streichenberger N, Texier P, Takissian J, et al. Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment. PLoS Pathog. 2016;12:e1005834 pubmed publisher
  • western blot; human; 1:500; fig s3
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6d
  • western blot; human; loading ...; fig 3a
Wu J, Lei H, Zhang J, Chen X, Tang C, Wang W, et al. Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation. Oncotarget. 2016;7:58995-59005 pubmed publisher
  • immunocytochemistry; purple sea urchin; 1:100; fig 2a
Oulhen N, Wessel G. Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin. Dev Biol. 2016;418:146-156 pubmed publisher
  • western blot; human; fig 8
Gunasekharan V, Li Y, Andrade J, Laimins L. Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle. PLoS Pathog. 2016;12:e1005747 pubmed publisher
  • western blot; human; loading ...; fig 1i
Mo Z, Zhang Q, Liu Z, Lauer J, Shi Y, Sun L, et al. Neddylation requires glycyl-tRNA synthetase to protect activated E2. Nat Struct Mol Biol. 2016;23:730-7 pubmed publisher
  • other; mouse; 1:500; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • immunoprecipitation; human; fig s3
  • western blot; human; fig 1
Ritho J, Arold S, Yeh E. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015;12:734-42 pubmed publisher
  • western blot; human; 1:1000; fig 2
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, et al. SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic Acids Res. 2015;43:7945-60 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 9
  • western blot; human; fig 4
Cho S, Yun S, Jo C, Lee D, Choi K, Song J, et al. SUMO1 promotes Aβ production via the modulation of autophagy. Autophagy. 2015;11:100-12 pubmed publisher
  • western blot; human; loading ...; fig 4Ai; S3B
Koh M, Nguyen V, Lemos R, Darnay B, Kiriakova G, Abdelmelek M, et al. Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma. Cancer Res. 2015;75:316-29 pubmed publisher
  • western blot; rat
Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed publisher
  • western blot; human
Bonacci T, Audebert S, Camoin L, Baudelet E, Bidaut G, Garcia M, et al. Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. J Proteome Res. 2014;13:2478-94 pubmed publisher
Wessels D, Lusche D, Voss E, Kuhl S, Buchele E, Klemme M, et al. Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44. PLoS ONE. 2017;12:e0173400 pubmed publisher
Yadav S, Magre I, Singh A, Khuperkar D, Joseph J. Regulation of aPKC activity by Nup358 dependent SUMO modification. Sci Rep. 2016;6:34100 pubmed publisher
Steven A, Leisz S, Sychra K, Hiebl B, Wickenhauser C, Mougiakakos D, et al. Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization. Oncotarget. 2016;7:52061-52084 pubmed publisher
Gehlert S, Klinz F, Willkomm L, Schiffer T, Suhr F, Bloch W. Intense Resistance Exercise Promotes the Acute and Transient Nuclear Translocation of Small Ubiquitin-Related Modifier (SUMO)-1 in Human Myofibres. Int J Mol Sci. 2016;17: pubmed publisher
Yazdian Robati R, Pourtaji A, Rashedinia M, Hosseinzadeh H, Ghorbani M, Razavi B, et al. Screening and identification of SUMP-proteins in sub-acute treatment with diazinon. Iran J Basic Med Sci. 2015;18:1240-4 pubmed
Tateossian H, Morse S, Simon M, Dean C, Brown S. Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung. Dis Model Mech. 2015;8:1531-42 pubmed publisher
Byun J, Son S, Cha M, Shong M, Hwang Y, Kim Y, et al. CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease. Cell Death Differ. 2015;22:959-73 pubmed publisher
Brechalov A, Georgieva S, Soshnikova N. Mammalian cells contain two functionally distinct PBAF complexes incorporating different isoforms of PHF10 signature subunit. Cell Cycle. 2014;13:1970-9 pubmed publisher
Biswas U, Wetzker C, Lange J, Christodoulou E, Seifert M, Beyer A, et al. Meiotic cohesin SMC1? provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. PLoS Genet. 2013;9:e1003985 pubmed publisher
Belaguli N, Zhang M, Brunicardi F, Berger D. Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation. PLoS ONE. 2012;7:e48019 pubmed publisher
product information
SKU :
4930P
Product-Name :
SUMO-1 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
Host :
Rabbit
Target :
SUMO-1
Primary-Protein :
SUMO1
Alt-Names :
DAP1,GAP modifying protein 1,GAP-modifying protein 1,GMP1,OFC10,PIC1,SENP2,SMT3,SMT3 homolog 3,SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae),SMT3C,SMT3H3,SUMO-1,SUMO1,Sentrin,Small ubiquitin-related modifier 1,UBL1,Ubiquitin-homology domain protein PIC1,Ubiquitin-like protein SMT3C,Ubiquitin-like protein UBL1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.