product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Caspase-8 Antibody (Mouse Specific)
catalog :
4927
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 3d
Tanzer M, Khan N, Rickard J, Etemadi N, Lalaoui N, Spall S, et al. Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ. 2017;24:481-491 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1g
LeBlanc L, Lee B, Yu A, Kim M, Kambhampati A, Dupont S, et al. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. elife. 2018;7: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Shen S, Li C, Dai M, Yan X. Induction of Huh?7 cell apoptosis by HCV core proteins via CK1??p53?Bid signaling pathway. Mol Med Rep. 2018;17:7559-7566 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Panigrahi S, Manterola M, Wolgemuth D. Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteins. PLoS ONE. 2017;12:e0173926 pubmed publisher
  • western blot; human; 1:1000; fig 1
Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Martin B, Wang C, Zhang C, Kang Z, Gulen M, Zepp J, et al. T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis. Nat Immunol. 2016;17:583-92 pubmed publisher
  • western blot; mouse; fig 1
Krajewska M, You Z, Rong J, Kress C, Huang X, Yang J, et al. Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. PLoS ONE. 2011;6:e24341 pubmed publisher
Ram D, Ilyukha V, Volkova T, Buzdin A, Tai A, Smirnova I, et al. Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo. Proc Natl Acad Sci U S A. 2016;113:1606-11 pubmed publisher
Bronner D, O Riordan M, He Y. Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis and pyroptosis. Front Cell Infect Microbiol. 2013;3:83 pubmed publisher
Granato M, Lacconi V, Peddis M, Lotti L, di Renzo L, Renzo L, et al. HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma. Cell Death Dis. 2013;4:e730 pubmed publisher
Sosna J, Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, et al. TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci. 2014;71:331-48 pubmed publisher
Lee Y, Yu Y, Gunawardena H, Xie L, Chen X. BCLAF1 is a radiation-induced H2AX-interacting partner involved in ?H2AX-mediated regulation of apoptosis and DNA repair. Cell Death Dis. 2012;3:e359 pubmed publisher
product information
SKU :
4927S
Product-Name :
Caspase-8 Antibody (Mouse Specific)
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
18, 45, 57
Host :
Rabbit
Target :
Casp8 mouse
Primary-Protein :
Casp8
Alt-Names :
CASP-8,Casp8,Caspase-8,Caspase-8 subunit p10,Caspase-8 subunit p18,FLICE,Fas-linked ICE-like protease,MACH,Mch5,caspase 8
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.