product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
RelB (C1E4) Rabbit mAb
catalog :
4922
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C1E4
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, chromatin immunoprecipitation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4a
Beug S, Cheung H, Sanda T, St Jean M, Beauregard C, Mamady H, et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 2019;12: pubmed publisher
  • western blot; human; loading ...; fig s8f
Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Hammers D, Sleeper M, Forbes S, Coker C, Jirousek M, Zimmer M, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016;1:e90341 pubmed publisher
  • western blot; human; loading ...; fig 5b
Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s8c
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 9a
Ta M, Schwensen K, Liuwantara D, Huso D, Watnick T, Rangan G. Constitutive renal Rel/nuclear factor-?B expression in Lewis polycystic kidney disease rats. World J Nephrol. 2016;5:339-57 pubmed publisher
  • western blot; human; 1:1000; fig 3
Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed publisher
  • western blot; mouse; fig 6
Ono R, Kaisho T, Tanaka T. PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm. Sci Rep. 2015;5:18327 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  • chromatin immunoprecipitation; human; fig 6d
Sibbesen N, Kopp K, Litvinov I, Jønson L, Willerslev Olsen A, Fredholm S, et al. Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma. Oncotarget. 2015;6:20555-69 pubmed
  • western blot; mouse; fig 3
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed publisher
  • western blot; human; loading ...; fig s4
Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Ma L, Pan Q, Sun F, Yu Y, Wang J. Cluster of differentiation 166 (CD166) regulates cluster of differentiation (CD44) via NF-?B in liver cancer cell line Bel-7402. Biochem Biophys Res Commun. 2014;451:334-8 pubmed publisher
  • western blot; mouse
Kim C, Pasparakis M. Epidermal p65/NF-?B signalling is essential for skin carcinogenesis. EMBO Mol Med. 2014;6:970-83 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
  • western blot; human
Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed publisher
  • western blot; mouse
Wu Y, Tan H, Huang Q, Sun X, Zhu X, Shen H. zVAD-induced necroptosis in L929 cells depends on autocrine production of TNF? mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ. 2011;18:26-37 pubmed publisher
Choi M, Maruyama T, Chun C, Park Y. Alleviation of Murine Osteoarthritis by Cartilage-Specific Deletion of I?B?. Arthritis Rheumatol. 2018;70:1440-1449 pubmed publisher
Kwong C, Gilman Sachs A, Beaman K. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011;186:1781-9 pubmed publisher
Xie S, Li J, Wang J, Wu Q, Yang P, Hsu H, et al. IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. J Immunol. 2010;184:2289-96 pubmed publisher
Hasler U, Leroy V, Jeon U, Bouley R, Dimitrov M, Kim J, et al. NF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem. 2008;283:28095-105 pubmed publisher
product information
SKU :
4922S
Product-Name :
RelB (C1E4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
70
Host :
Rabbit
Target :
RelB
Primary-Protein :
RelB
Alt-Names :
I-Rel,IREL,REL-B,RELB,Transcription factor RelB,v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3),v-rel reticuloendotheliosis viral oncogene homolog B,v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.