| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 1a
| Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed publisher |
- immunocytochemistry knockout validation; mouse; 1:200; loading ...; fig s7a
- immunocytochemistry; human; 1:200; loading ...; fig s7c
- western blot; human; 1:1000; loading ...; fig s9a
| Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed publisher |
- western blot knockout validation; mouse; fig 1
| Chen Y, Wei H, Liu F, Guan J. Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling. J Biol Chem. 2014;289:1164-73 pubmed publisher |
- western blot; human; loading ...; fig ev3e
| Hartleben G, Muller C, Kramer A, Schimmel H, Zidek L, Dornblut C, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018;37: pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; mouse; loading ...; fig 1a
| Zou J, Zhang B, Gutmann D, Wong M. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. Epilepsia. 2017;58:2053-2063 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- western blot; human; fig 1a
| Cao J, Tyburczy M, Moss J, Darling T, Widlund H, Kwiatkowski D. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. J Clin Invest. 2017;127:349-364 pubmed publisher |
- western blot; mouse; fig 6
| Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed publisher |
- western blot; human; 1:1000; fig 2e
| Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed publisher |
- western blot; human; fig 4
| Bai Y, Xuan B, Liu H, Zhong J, Yu D, Qian Z. Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38. J Virol. 2015;89:7625-35 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Bartley C, O Keefe R, Bordey A. FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity. PLoS ONE. 2014;9:e96956 pubmed publisher |
- western blot; human; fig 4d
| Kuo H, Lee D, Chen C, Liu M, Chou C, Lee H, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal. 2010;3:ra9 pubmed publisher |
| Sager R, Woodford M, Shapiro O, Mollapour M, Bratslavsky G. Sporadic renal angiomyolipoma in a patient with Birt-Hogg-Dubé: chaperones in pathogenesis. Oncotarget. 2018;9:22220-22229 pubmed publisher |
| Hägglund A, Jones I, Carlsson L. A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017;10:245-257 pubmed publisher |
| Pema M, Drusian L, Chiaravalli M, Castelli M, Yao Q, Ricciardi S, et al. mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex. Nat Commun. 2016;7:10786 pubmed publisher |
| Magri L, Cominelli M, Cambiaghi M, Cursi M, Leocani L, Minicucci F, et al. Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. Dis Model Mech. 2013;6:1185-97 pubmed publisher |
| Jozefczuk J, Kashofer K, Ummanni R, Henjes F, Rehman S, Geenen S, et al. A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells. Front Physiol. 2012;3:339 pubmed publisher |
| Yang J, Madupu R, Durkin A, Ekborg N, Pedamallu C, Hostetler J, et al. The complete genome of Teredinibacter turnerae T7901: an intracellular endosymbiont of marine wood-boring bivalves (shipworms). PLoS ONE. 2009;4:e6085 pubmed publisher |
