product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Stat3 (79D7) Rabbit mAb
catalog :
4904S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 30
Published Application/Species/DilutionReference
  • immunohistochemistry - free floating section; rat; 1:300
Moravcová S, Cervena K, Pačesová D, Bendova Z. Identification of STAT3 and STAT5 proteins in the rat suprachiasmatic nucleus and the Day/Night difference in astrocytic STAT3 phosphorylation in response to lipopolysaccharide. J Neurosci Res. 2016;94:99-108 pubmed publisher
  • western blot; mouse; 1:1000; fig 7D
Liu S, Li Q, Zhang M, Mao-Ying Q, Hu L, Wu G, et al. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Sci Rep. 2016;6:28956 pubmed publisher
  • western blot; mouse; 1:2000; fig 7
Nikolakopoulou A, Koeppen J, Garcia M, Leish J, Obenaus A, Ethell I. Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury. ASN Neuro. 2016;8: pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Liu S, Mi W, Li Q, Zhang M, Han P, Hu S, et al. Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice. Anesthesiology. 2015;123:1154-69 pubmed publisher
  • western blot; mouse
Coorey N, Shen W, Zhu L, Gillies M. Differential Expression of IL-6/gp130 Cytokines, Jak-STAT Signaling and Neuroprotection After Müller Cell Ablation in a Transgenic Mouse Model. Invest Ophthalmol Vis Sci. 2015;56:2151-61 pubmed publisher
  • western blot; human; fig 1
Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  • western blot; African green monkey
  • immunocytochemistry; African green monkey
García-Hernández V, Flores-Maldonado C, Rincon-Heredia R, Verdejo-Torres O, Bonilla-Delgado J, Meneses-Morales I, et al. EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells. J Cell Physiol. 2015;230:105-15 pubmed publisher
  • western blot; rat
Cai W, Kang K, Huang W, Liang J, Feng Y, Liu G, et al. CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury. J Cell Mol Med. 2015;19:1825-35 pubmed publisher
  • western blot; mouse; fig s5
Cattoglio C, Zhang E, Grubisic I, Chiba K, Fong Y, Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A. 2015;112:E2317-26 pubmed publisher
  • western blot; human; fig 6
Xiao W, Wu K, Yin M, Han S, Ding Y, Qiao A, et al. Wogonin Inhibits Tumor-derived Regulatory Molecules by Suppressing STAT3 Signaling to Promote Tumor Immunity. J Immunother. 2015;38:167-84 pubmed publisher
  • western blot; mouse; 1:1000
Taylor J, Minter M, Newman A, Zhang M, Adlard P, Crack P. Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol Aging. 2014;35:1012-23 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1
  • chromatin immunoprecipitation; mouse
  • western blot; mouse; 1:1000; fig 1
Tyzack G, Sitnikov S, Barson D, Adams-Carr K, Lau N, Kwok J, et al. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nat Commun. 2014;5:4294 pubmed publisher
  • western blot; mouse
Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB. J Hepatol. 2014;60:306-12 pubmed publisher
  • western blot; human
Waitkus M, Chandrasekharan U, Willard B, Tee T, Hsieh J, Przybycin C, et al. Signal integration and gene induction by a functionally distinct STAT3 phosphoform. Mol Cell Biol. 2014;34:1800-11 pubmed publisher
Naranbhai V, Fairfax B, Makino S, Humburg P, Wong D, Ng E, et al. Genomic modulators of gene expression in human neutrophils. Nat Commun. 2015;6:7545 pubmed publisher
Das L, Rosenjack J, Au L, Galle P, Hansen M, Cathcart M, et al. Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency. J Invest Dermatol. 2015;135:389-99 pubmed publisher
Minter M, Main B, Brody K, Zhang M, Taylor J, Crack P. Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro. J Neuroinflammation. 2015;12:71 pubmed publisher
Milner J, Vogel T, Forbes L, Ma C, Stray-Pedersen A, Niemela J, et al. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood. 2015;125:591-9 pubmed publisher
Folgiero V, Goffredo B, Filippini P, Masetti R, Bonanno G, Caruso R, et al. Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia. Oncotarget. 2014;5:2052-64 pubmed
Yoshida R, Nakayama H, Nagata M, Hirosue A, Tanaka T, Kawahara K, et al. Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma. Br J Cancer. 2014;111:2308-15 pubmed publisher
Sadighi Akha A, Theriot C, Erb-Downward J, McDermott A, Falkowski N, Tyra H, et al. Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology. 2013;140:111-22 pubmed publisher
Messenger S, Ciriello J. Effects of intermittent hypoxia on leptin signalling in the carotid body. Neuroscience. 2013;232:216-25 pubmed publisher
Lo J, Patel V, Wang Z, Levasseur J, Kaufman S, Penninger J, et al. Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats. Exp Physiol. 2013;98:109-22 pubmed publisher
Liu B, Stoop J, Huizinga T, Toes R. IL-21 enhances the activity of the TLR-MyD88-STAT3 pathway but not the classical TLR-MyD88-NF-κB pathway in human B cells to boost antibody production. J Immunol. 2013;191:4086-94 pubmed publisher
Kanari Y, Sato Y, Aoyama S, Muta T. Thioredoxin-interacting protein gene expression via MondoA is rapidly and transiently suppressed during inflammatory responses. PLoS ONE. 2013;8:e59026 pubmed publisher
da Cunha J, da Costa-Neves A, Kerkis I, da Silva M. Pluripotent stem cell transcription factors during human odontogenesis. Cell Tissue Res. 2013;353:435-41 pubmed publisher
Ahluwalia M, Donovan H, Singh N, Butcher L, Erusalimsky J. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010;8:2252-61 pubmed publisher
Surdziel E, Cabanski M, Dallmann I, Lyszkiewicz M, Krueger A, Ganser A, et al. Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways. Blood. 2011;117:4338-48 pubmed publisher
Naraoka T, Ishibashi Y, Tsuda E, Yamamoto Y, Kusumi T, Kakizaki I, et al. Time-dependent gene expression and immunohistochemical analysis of the injured anterior cruciate ligament. Bone Joint Res. 2012;1:238-44 pubmed publisher
Yanaihara N, Anglesio M, Ochiai K, Hirata Y, Saito M, Nagata C, et al. Cytokine gene expression signature in ovarian clear cell carcinoma. Int J Oncol. 2012;41:1094-100 pubmed publisher
product information
SKU :
4904S
Product-Name :
Stat3 (79D7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
79, 86
Host :
Rabbit
Target :
STAT3
Primary-Protein :
STAT3
Alt-Names :
APRF,Acute-phase response factor,DNA-binding protein APRF,FLJ20882,HIES,MGC16063,STAT3,Signal transducer and activator of transcription 3,signal transducer and activator of transcription 3 (acute-phase response factor)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.